(Q39341454)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634635%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Deciphering biased-agonism complexity reveals a new active AT1 receptor entity (English)

1 reference

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2 February 2020

1 reference

4

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2 February 2020

Atul Pathak

9

1 reference

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2 February 2020

Jean-Michel Sénard

11

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2 February 2020

Céline Galès

12

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2 February 2020

author name string

Aude Saulière

1

1 reference

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2 February 2020

Morgane Bellot

2

1 reference

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2 February 2020

Hervé Paris

3

1 reference

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2 February 2020

Frédéric Finana

5

1 reference

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2 February 2020

Jonas T Hansen

6

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2 February 2020

Marie-Hélène Seguelas

8

1 reference

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2 February 2020

Jakob L Hansen

10

1 reference

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2 February 2020

Marie-Françoise Altié

7

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2 February 2020

publication date

27 May 2012

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2 February 2020

published in

Nature Chemical Biology

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2 February 2020

volume

8

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2 February 2020

issue

7

1 reference

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2 February 2020

page(s)

622-630

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https://scigraph.springernature.com/pub.10.1038/nchembio.961

2 February 2020

exact match

0 references

cites work

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Functional Selectivity and Classical Concepts of Quantitative Pharmacology

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12 December 2020

The angiotensin type 1 receptor activates extracellular signal-regulated kinases 1 and 2 by G protein-dependent and -independent pathways in cardiac myocytes and langendorff-perfused hearts.

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Distinct signaling profiles of beta1 and beta2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of efficacy

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12 December 2020

Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes

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12 December 2020

A novel Galphaq/11-selective inhibitor

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12 December 2020

Analysis of G protein betagamma dimer formation in live cells using multicolor bimolecular fluorescence complementation demonstrates preferences of beta1 for particular gamma subunits

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12 December 2020

Distinct conformational changes in beta-arrestin report biased agonism at seven-transmembrane receptors.

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12 December 2020

Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A.

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12 December 2020

Cardiac-specific overexpression of AT1 receptor mutant lacking G alpha q/G alpha i coupling causes hypertrophy and bradycardia in transgenic mice.

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12 December 2020

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12 December 2020

Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2.

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12 December 2020

Probing the activation-promoted structural rearrangements in preassembled receptor-G protein complexes.

1 reference

12 December 2020

Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands

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12 December 2020

Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor

1 reference

12 December 2020

Transfected aequorin in the measurement of cytosolic Ca2+ concentration ([Ca2+]c). A critical evaluation.

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12 December 2020

beta-arrestins: traffic cops of cell signaling

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12 December 2020

Functional selectivity and biased receptor signaling.

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12 December 2020

Angiotensin II enhances adenylyl cyclase signaling via Ca2+/calmodulin. Gq-Gs cross-talk regulates collagen production in cardiac fibroblasts

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12 December 2020

AT1 receptor Gαq protein-independent signalling transcriptionally activates only a few genes directly, but robustly potentiates gene regulation from the β2-adrenergic receptor

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12 December 2020

Side-chain substitutions within angiotensin II reveal different requirements for signaling, internalization, and phosphorylation of type 1A angiotensin receptors.

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12 December 2020

The oxytocin receptor antagonist atosiban inhibits cell growth via a "biased agonist" mechanism

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12 December 2020

beta-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking

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12 December 2020

Selectively engaging β-arrestins at the angiotensin II type 1 receptor reduces blood pressure and increases cardiac performance.

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12 December 2020

Transfected muscarinic acetylcholine receptors selectively couple to Gi-type G proteins and Gq/11.

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12 December 2020

Probing heterotrimeric G protein activation: applications to biased ligands.

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12 December 2020

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12 December 2020

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12 December 2020

G protein heterotrimer Galpha13beta1gamma3 couples the angiotensin AT1A receptor to increases in cytoplasmic Ca2+ in rat portal vein myocytes

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12 December 2020

Bioluminescence resonance energy transfer assays reveal ligand-specific conformational changes within preformed signaling complexes containing delta-opioid receptors and heterotrimeric G proteins.

1 reference

12 December 2020

Dosage-dependent switch from G protein-coupled to G protein-independent signaling by a GPCR

1 reference

12 December 2020

Combining resonance energy transfer methods reveals a complex between the alpha2A-adrenergic receptor, Galphai1beta1gamma2, and GRK2.

1 reference

12 December 2020