(Q36290216)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16234342%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

review article

1 reference

title

G-protein-coupled receptors in drug discovery: nanosizing using cell-free technologies and molecular biology approaches (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16234342%20AND%20SRC:MED&resulttype=core&format=json

G protein-coupled receptor

8 January 2020

main subject

0 references

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16234342%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

author name string

Amanda L Aloia

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16234342%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Olgatina Bucco

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16234342%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Richard V Glatz

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16234342%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Edward J McMurchie

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16234342%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

publication date

18 October 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16234342%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biomolecular Screening

8 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16234342%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16234342%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16234342%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

page(s)

765-779

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16234342%20AND%20SRC:MED&resulttype=core&format=json

Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function

8 January 2020

cites work

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Structural genomics of GPCRs

21 January 2018

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The G protein-coupled receptor repertoires of human and mouse

21 January 2018

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Homogeneous fluorescence readouts for miniaturized high-throughput screening: theory and practice

21 January 2018

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HTS in the new millennium: the role of pharmacology and flexibility

21 January 2018

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Applications of bioluminescence- and fluorescence resonance energy transfer to drug discovery at G protein-coupled receptors

21 January 2018

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Direct optical recording of intrinsic efficacy at a G protein-coupled receptor

21 January 2018

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Chimaeric G alpha proteins: their potential use in drug discovery

21 January 2018

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Modern drug development from traditional medicinal plants using radioligand receptor-binding assays.

21 January 2018

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Peptide protein binding assay using ImageFlashPlates or Imaging Beads

21 January 2018

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 January 2018

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Fluorescent ligands, antibodies, and proteins for the study of receptors

21 January 2018

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Fluorescence polarization assays for high throughput screening of G protein-coupled receptors.

21 January 2018

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Use of fluorescence polarization detection for the measurement of fluopeptidetm binding to G protein-coupled receptors

21 January 2018

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Endothelin receptor in virus-like particles: ligand binding observed by fluorescence fluctuation spectroscopy.

21 January 2018

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High throughput screening of G-protein coupled receptors via flow cytometry

21 January 2018

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Paramagnetic proteoliposomes containing a pure, native, and oriented seven-transmembrane segment protein, CCR5.

21 January 2018

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Membrane protein microarrays.

21 January 2018

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G-protein-coupled receptor microarrays

21 January 2018

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Atomic force microscopy and drug discovery

21 January 2018

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An overview of the biophysical applications of atomic force microscopy.

21 January 2018

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The G protein-coupled receptor rhodopsin in the native membrane

21 January 2018

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Flow-mediated on-surface reconstitution of G-protein coupled receptors for applications in surface plasmon resonance biosensors.

21 January 2018

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Plasmon-waveguide resonance studies of ligand binding to the human beta 2-adrenergic receptor

21 January 2018

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Different structural states of the proteolipid membrane are produced by ligand binding to the human delta-opioid receptor as shown by plasmon-waveguide resonance spectroscopy

21 January 2018

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Techniques: plasmon-waveguide resonance (PWR) spectroscopy as a tool to study ligand-GPCR interactions

21 January 2018

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Adapting atomic force microscopy for cell biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Functional immobilization of a ligand-activated G-protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Principles: extending the utility of [35S]GTP gamma S binding assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

The [35S]GTPγS binding assay: approaches and applications in pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Detection of glucagon-dependent GTPgammaS binding in high-throughput format

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

The antibody-capture [(35)S]GTPgammaS scintillation proximity assay: a powerful emerging technique for analysis of GPCR pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Carbostyril derivatives as antenna molecules for luminescent lanthanide chelates

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Amine-reactive forms of a luminescent diethylenetriaminepentaacetic acid chelate of terbium and europium: attachment to DNA and energy transfer measurements

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Principles and biophysical applications of lanthanide-based probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Conformational changes between the active-site and regulatory light chain of myosin as determined by luminescence resonance energy transfer: the effect of nucleotides and actin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Thiol-reactive luminescent lanthanide chelates: part 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Luminescence energy transfer using a terbium chelate: improvements on fluorescence energy transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Nonradioactive GTP binding assay to monitor activation of g protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Assessing activation of the human neuropeptide FF2 receptor with a non-radioactive GTP binding assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Partial G protein activation by fluorescent guanine nucleotide analogs. Evidence for a triphosphate-bound but inactive state.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Fluorescent BODIPY-GTP analogs: real-time measurement of nucleotide binding to G proteins

21 January 2018

1 reference

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Established and emerging fluorescence-based assays for G-protein function: heterotrimeric G-protein alpha subunits and regulator of G-protein signaling (RGS) proteins.

21 January 2018

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Regulators of G-protein signalling as new central nervous system drug targets.

21 January 2018

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Micropatterned immobilization of a G protein-coupled receptor and direct detection of G protein activation.

21 January 2018

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Ligand-receptor-G-protein molecular assemblies on beads for mechanistic studies and screening by flow cytometry.

21 January 2018

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Techniques: GPCR assembly, pharmacology and screening by flow cytometry.

21 January 2018

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Real-time analysis of G protein-coupled receptor reconstitution in a solubilized system.

21 January 2018

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Fluorescence analysis of receptor-G protein interactions in cell membranes.

21 January 2018

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Assembly of G protein-coupled receptors onto nanosized bacterial magnetic particles using Mms16 as an anchor molecule.

21 January 2018

1 reference

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Cellular signaling by an agonist-activated receptor/Gs alpha fusion protein

21 January 2018

1 reference

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Insights into ligand pharmacology using receptor-G-protein fusion proteins

21 January 2018

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G protein-coupled receptor fusion proteins in drug discovery

21 January 2018

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High-content assays for ligand regulation of G-protein-coupled receptors

21 January 2018

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Measurement of the millisecond activation switch of G protein-coupled receptors in living cells

21 January 2018

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G16 as a universal G protein adapter: implications for agonist screening strategies.

21 January 2018

1 reference

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Is Galpha16 the optimal tool for fishing ligands of orphan G-protein-coupled receptors?

21 January 2018

1 reference

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Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Functional characterization of a series of mutant G protein alphaq subunits displaying promiscuous receptor coupling properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

G alpha 16, a G protein alpha subunit specifically expressed in hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

G protein subunits and the stimulation of phospholipase C by Gs-and Gi-coupled receptors: Lack of receptor selectivity of Galpha(16) and evidence for a synergic interaction between Gbeta gamma and the alpha subunit of a receptor activated G protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Production of G-protein-coupled receptors in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Heterologous expression of limulus rhodopsin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Structural genomics on membrane proteins: mini review

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Purification and characterization of the human adenosine A(2a) receptor functionally expressed in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

The conformation of neurotensin bound to its G protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Homo- and hetero-oligomeric interactions between G-protein-coupled receptors in living cells monitored by two variants of bioluminescence resonance energy transfer (BRET): hetero-oligomers between receptor subtypes form more efficiently than between

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Heterologous expression of G-protein-coupled receptors: comparison of expression systems from the standpoint of large-scale production and purification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Semliki Forest virus vectors for rapid and high-level expression of integral membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Transient overexpression of kappa and mu opioid receptors using recombinant adenovirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Reconstitution of mutant V2 vasopressin receptors by adenovirus-mediated gene transfer. Molecular basis and clinical implication

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor has broad signaling effects in primary effusion lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Orientation-dependent gene expression with Epstein-Barr virus-derived vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Proteomics: quantitative and physical mapping of cellular proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

BacMam recombinant baculoviruses in G protein-coupled receptor drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Heterologous expression of G protein-coupled receptors in U-2 OS osteosarcoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

G protein-coupled receptor overexpression with the baculovirus-insect cell system: a tool for structural and functional studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Manipulation of baculovirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Baculovirus diversity and molecular biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Role of palmitoylation/depalmitoylation reactions in G-protein-coupled receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Parameters influencing human mu opioid receptor over-expression in baculovirus-infected insect cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Recovery of homogeneous and functional beta 2-adrenergic receptors from extracellular baculovirus particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Expression and recovery of functional G-protein-coupled receptors using baculovirus expression systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Glycosylation, palmitoylation, and localization of the human D2S receptor in baculovirus-infected insect cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Watching proteins in the wild: fluorescence methods to study protein dynamics in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Reversible site-selective labeling of membrane proteins in live cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Large-scale overproduction, functional purification and ligand affinities of the His-tagged human histamine H1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Stable and functional immobilization of histidine-tagged proteins via multivalent chelator headgroups on a molecular poly(ethylene glycol) brush

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

The enzymatic biotinylation of proteins: a post-translational modification of exceptional specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

The green fluorescent protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

The molecular properties and applications of Anthozoa fluorescent proteins and chromoproteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

New biarsenical ligands and tetracysteine motifs for protein labeling in vitro and in vivo: synthesis and biological applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Selective photolabeling of proteins using photoactivatable GFP.

21 January 2018

1 reference

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GFP-like chromoproteins as a source of far-red fluorescent proteins

21 January 2018

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An optical marker based on the UV-induced green-to-red photoconversion of a fluorescent protein

21 January 2018

1 reference

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Diversity and evolution of the green fluorescent protein family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Multiphoton-evoked color change of DsRed as an optical highlighter for cellular and subcellular labeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Kindling fluorescent proteins for precise in vivo photolabeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Chromophore environment provides clue to "kindling fluorescent protein" riddle

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

A powerful combinatorial screen to identify high-affinity terbium(III)-binding peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Structural implications of fluorescence quenching in the Shaker K+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517

Thiol-reactive lanthanide chelates for phasing protein X-ray diffraction data

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105280517