(Q39341462)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Viktoria Konya

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Angel Gonzalez

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Trond Ulven

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Leonardo Pardo

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Akos Heinemann

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

author name string

Stefanie Blättermann

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Lucas Peters

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Philipp Aaron Ottersbach

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

C David Weaver

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Ralf Schröder

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Rahul Tyagi

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Petra Luschnig

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Jürgen Gäb

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Stephanie Hennen

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Klaus Mohr

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Michael Gütschow

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Evi Kostenis

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

publication date

27 May 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

published in

Nature Chemical Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

page(s)

631-638

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22634634%20AND%20SRC:MED&resulttype=core&format=json

The structure and function of G-protein-coupled receptors

2 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Structure of a nanobody-stabilized active state of the β(2) adrenoceptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

How many drug targets are there?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

How receptors talk to trimeric G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Teaching old receptors new tricks: biasing seven-transmembrane receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Therapeutic potential of β-arrestin- and G protein-biased agonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Versatility of GPCR recognition by drugs: from biological implications to therapeutic relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Cellular assays as portals to seven-transmembrane receptor-based drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

When simple agonism is not enough: emerging modalities of GPCR ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Functional Selectivity and Classical Concepts of Quantitative Pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

The beta-arrestin pathway-selective type 1A angiotensin receptor (AT1A) agonist [Sar1,Ile4,Ile8]angiotensin II regulates a robust G protein-independent signaling network.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Dualsteric GPCR targeting: a novel route to binding and signaling pathway selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

The evasive nature of drug efficacy: implications for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Identification of an antithrombotic allosteric modulator that acts through helix 8 of PAR1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Multiple GPCR conformations and signalling pathways: implications for antagonist affinity estimates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

A novel, conformation-specific allosteric inhibitor of the tachykinin NK2 receptor (NK2R) with functionally selective properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Identification of a novel human eicosanoid receptor coupled to G(i/o)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Expression and characterization of a 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid receptor highly expressed on human eosinophils and neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

5-Oxo-ETE and the OXE receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

ZINC--a free database of commercially available compounds for virtual screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Pertussis toxin-sensitive activation of phospholipase C by the C5a and fMet-Leu-Phe receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

G protein βγ subunits: central mediators of G protein-coupled receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Roles of phospholipase C beta2 in chemoattractant-elicited responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Differential targeting of Gbetagamma-subunit signaling with small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

The beta gamma subunits of GTP-binding proteins activate the muscarinic K+ channel in heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Gating of GIRK channels: details of an intricate, membrane-delimited signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

A novel assay of Gi/o-linked G protein-coupled receptor coupling to potassium channels provides new insights into the pharmacology of the group III metabotropic glutamate receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Probing the activation-promoted structural rearrangements in preassembled receptor-G protein complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Crystal structure of the β2 adrenergic receptor-Gs protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Real-time monitoring of receptor and G-protein interactions in living cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Gi protein activation in intact cells involves subunit rearrangement rather than dissociation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Deconvolution of complex G protein-coupled receptor signaling in live cells using dynamic mass redistribution measurements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Discovery of potent and selective agonists for the free fatty acid receptor 1 (FFA(1)/GPR40), a potential target for the treatment of type II diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Applying label-free dynamic mass redistribution technology to frame signaling of G protein-coupled receptors noninvasively in living cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

Identification of Selective Basophil Chemoattractants in Human Nasal Polyps as Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.962

PGD2 metabolism in plasma: Kinetics and relationship with bioactivity on DP1 and CRTH2 receptors

21 January 2018

1 reference

12 December 2020

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

1 reference

12 December 2020

Roles of phospholipid signaling in chemoattractant-induced responses

1 reference

12 December 2020

Identification of indole derivatives exclusively interfering with a G protein-independent signaling pathway of the prostaglandin D2 receptor CRTH2.

1 reference

12 December 2020

Activation of G-protein Galpha subunits by receptors through Galpha-Gbeta and Galpha-Ggamma interactions

1 reference

12 December 2020

The coupling of 5-oxo-eicosanoid receptors to heterotrimeric G proteins

1 reference

12 December 2020