(Q39349232)

English

LASS2 enhances chemosensitivity of breast cancer by counteracting acidic tumor microenvironment through inhibiting activity of V-ATPase proton pump

scientific article published on 14 May 2012

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scholarly article

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11 September 2017

LASS2 enhances chemosensitivity of breast cancer by counteracting acidic tumor microenvironment through inhibiting activity of V-ATPase proton pump (English)

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Europe PubMed Central

PubMed publication ID

11 September 2017

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S Fan

1

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11 September 2017

Y Niu

2

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11 September 2017

N Tan

3

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11 September 2017

Z Wu

4

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11 September 2017

Y Wang

5

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11 September 2017

H You

6

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11 September 2017

R Ke

7

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11 September 2017

J Song

8

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11 September 2017

Q Shen

9

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11 September 2017

W Wang

10

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11 September 2017

G Yao

11

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11 September 2017

H Shu

12

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11 September 2017

H Lin

13

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11 September 2017

M Yao

14

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11 September 2017

Z Zhang

15

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11 September 2017

J Gu

16

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11 September 2017

W Qin

17

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11 September 2017

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publication date

14 May 2012

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11 September 2017

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11 September 2017

32

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11 September 2017

13

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11 September 2017

1682-1690

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11 September 2017

https://scigraph.springernature.com/pub.10.1038/onc.2012.183

0 references

Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths

1 reference

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Multidrug resistance in cancer: role of ATP-dependent transporters

1 reference

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Reversal of doxorubicin resistance in breast cancer cells by photochemical internalization.

1 reference

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Small interfering RNA targeting the subunit ATP6L of proton pump V-ATPase overcomes chemoresistance of breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.183

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Drug resistance and the solid tumor microenvironment

1 reference

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Separate Roles for the Golgi Apparatus and Lysosomes in the Sequestration of Drugs in the Multidrug-resistant Human Leukemic Cell Line HL-60

1 reference

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Tumor acidity, ion trapping and chemotherapeutics. I. Acid pH affects the distribution of chemotherapeutic agents in vitro

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Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs

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Examination by laser scanning confocal fluorescence imaging microscopy of the subcellular localisation of anthracyclines in parent and multidrug resistant cell lines

1 reference

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Resistance mechanisms associated with altered intracellular distribution of anticancer agents.

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Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling

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The gene encoding vacuolar H(+)-ATPase subunit C is overexpressed in multidrug-resistant HL60 cells

1 reference

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Enhanced expression of the human vacuolar H+-ATPase c subunit gene (ATP6L) in response to anticancer agents.

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Inhibitors of vacuolar H+-ATPase impair the preferential accumulation of daunomycin in lysosomes and reverse the resistance to anthracyclines in drug-resistant renal epithelial cells.

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Cloning, mapping, and characterization of a human homologue of the yeast longevity assurance gene LAG1

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Ceramide synthases and ceramide levels are increased in breast cancer tissue

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Increased ceramide synthase 2 and 6 mRNA levels in breast cancer tissues and correlation with sphingosine kinase expression

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IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer

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Targeting vacuolar H+-ATPases as a new strategy against cancer

1 reference

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Enhancement of chemotherapy by manipulation of tumour pH.

1 reference

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21 January 2018

Drug resistance and cellular adaptation to tumor acidic pH microenvironment

1 reference

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Prolonged drug selection of breast cancer cells and enrichment of cancer stem cell characteristics

1 reference

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The HPV-16 E5 oncogene and bafilomycin A(1) influence cell motility

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Thymidine phosphorylase expression and benefit from capecitabine in patients with advanced breast cancer

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FGFR4 Arg388 allele is associated with resistance to adjuvant therapy in primary breast cancer

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Expression of endothelin-A-receptor predicts unfavourable response to neoadjuvant chemotherapy in locally advanced breast cancer

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21 January 2018

The growth and metastasis of human hepatocellular carcinoma xenografts are inhibited by small interfering RNA targeting to the subunit ATP6L of proton pump

1 reference

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21 January 2018

Proton pump inhibitors induce apoptosis of human B-cell tumors through a caspase-independent mechanism involving reactive oxygen species.

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21 January 2018

KiSS1 mediates platinum sensitivity and metastasis suppression in head and neck squamous cell carcinoma

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p120 catenin is essential for mesenchymal cadherin-mediated regulation of cell motility and invasiveness

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21 January 2018

Deregulation of the Pit-1 transcription factor in human breast cancer cells promotes tumor growth and metastasis

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Acetylcholinesterase, a key prognostic predictor for hepatocellular carcinoma, suppresses cell growth and induces chemosensitization

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Antitumor effects of doxorubicin followed by zoledronic acid in a mouse model of breast cancer.

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Role of carbonic anhydrase IX expression in prediction of the efficacy and outcome of primary epirubicin/tamoxifen therapy for breast cancer

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pH and drug resistance. II. turnover of acidic vesicles and resistance to weakly basic chemotherapeutic drugs

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31 March 2020

Vacuolar-type H+-ATPases at the plasma membrane regulate pH and cell migration in microvascular endothelial cells

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Effect of a novel vacuolar-H+-ATPase inhibitor on cell and tumor response to camptothecins

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Gain of miR-151 on chromosome 8q24.3 facilitates tumour cell migration and spreading through downregulating RhoGDIA

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Identification of AFAP1L1 as a prognostic marker for spindle cell sarcomas

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REIC/Dkk-3 overexpression downregulates P-glycoprotein in multidrug-resistant MCF7/ADR cells and induces apoptosis in breast cancer

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31 March 2020

Identifiers

10.1038/ONC.2012.183

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

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