(Q39354809)

English

Impairment of adenylyl cyclase 2 function and expression in hypoxanthine phosphoribosyltransferase-deficient rat B103 neuroblastoma cells as model for Lesch-Nyhan disease: BODIPY-forskolin as pharmacological tool

scientific article published on 3 May 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Impairment of adenylyl cyclase 2 function and expression in hypoxanthine phosphoribosyltransferase-deficient rat B103 neuroblastoma cells as model for Lesch-Nyhan disease: BODIPY-forskolin as pharmacological tool (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Lesch-Nyhan syndrome

0 references

1 reference

based on heuristic

inferred from title

author name string

Liz Kinast

1

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Juliane von der Ohe

2

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Heike Burhenne

3

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Roland Seifert

4

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

publication date

3 May 2012

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Naunyn-Schmiedeberg's Archives of Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

385

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

671-683

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

https://scigraph.springernature.com/pub.10.1007/s00210-012-0759-6

0 references

Human bronchial smooth muscle cells express adenylyl cyclase isoforms 2, 4, and 6 in distinct membrane microdomains

1 reference

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21 January 2018

Interaction of delta-9-tetrahydrocannabinol with rat B103 neuroblastoma cells

1 reference

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21 January 2018

Persistent cAMP-signals triggered by internalized G-protein-coupled receptors

1 reference

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21 January 2018

Inhibition of protein kinase C promotes differentiation of neuroblastoma × glioma NG108-15 hybrid cells

1 reference

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21 January 2018

Hypoxanthine-guanine phosphoribosyltransferase-deficiency produces aberrant neurite outgrowth of rodent neuroblastoma used to model the neurological disorder Lesch Nyhan syndrome

1 reference

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21 January 2018

Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling

1 reference

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Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation

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21 January 2018

Methylmercury genotoxicity: a novel effect in human cell lines of the central nervous system.

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The PRPP synthetase spectrum: what does it demonstrate about nucleotide syndromes?

1 reference

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21 January 2018

Impaired P2X and P2Y receptor-mediated signaling in HPRT-deficient B103 neuroblastoma cells

1 reference

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21 January 2018

Impact of divalent metal ions on regulation of adenylyl cyclase isoforms by forskolin analogs.

1 reference

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21 January 2018

Low-affinity interactions of BODIPY-FL-GTPgammaS and BODIPY-FL-GppNHp with G(i)- and G(s)-proteins

1 reference

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21 January 2018

GDP affinity and order state of the catalytic site are critical for function of xanthine nucleotide-selective Galphas proteins

1 reference

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21 January 2018

Differential inhibition of adenylyl cyclase isoforms and soluble guanylyl cyclase by purine and pyrimidine nucleotides.

1 reference

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21 January 2018

Differential interactions of G-proteins and adenylyl cyclase with nucleoside 5'-triphosphates, nucleoside 5'-[gamma-thio]triphosphates and nucleoside 5'-[beta,gamma-imido]triphosphates.

1 reference

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21 January 2018

G proteins: transducers of receptor-generated signals

1 reference

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21 January 2018

Characterization of mouse heart adenylyl cyclase.

1 reference

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21 January 2018

Deficiency of the housekeeping gene hypoxanthine-guanine phosphoribosyltransferase (HPRT) dysregulates neurogenesis

1 reference

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21 January 2018

MicroRNA-mediated dysregulation of neural developmental genes in HPRT deficiency: clues for Lesch-Nyhan disease?

1 reference

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21 January 2018

Combined preconditioning and in vivo chemoselection with 6-thioguanine alone achieves highly efficient reconstitution of normal hematopoiesis with HPRT-deficient bone marrow

1 reference

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21 January 2018

A rapid, nongenomic action of glucocorticoids in rat B103 neuroblastoma cells

1 reference

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21 January 2018

The nuclear inclusion a (NIa) protease of turnip mosaic virus (TuMV) cleaves amyloid-β

1 reference

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21 January 2018

Advances in understanding behavioral phenotypes in neurogenetic syndromes

1 reference

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21 January 2018

Differential regulation of adenylyl cyclases by Galphas

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0759-6

21 January 2018

Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cells

1 reference

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21 January 2018

Anandamide-induced neuroblastoma cell rounding via the CB1 cannabinoid receptors

1 reference

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21 January 2018

Spontaneous and cAMP-dependent induction of a resting phase and neurite formation in cell hybrids between human neuroblastoma cells and thymidine auxotrophs of rat nerve-like cells

1 reference

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21 January 2018

Motor dysfunction in type 5 adenylyl cyclase-null mice

1 reference

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21 January 2018

Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers

1 reference

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21 January 2018

Lesch-Nyhan disease: from mechanism to model and back again

1 reference

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21 January 2018

HPRT deficiency coordinately dysregulates canonical Wnt and presenilin-1 signaling: a neuro-developmental regulatory role for a housekeeping gene?

1 reference

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21 January 2018

Constitutively active lysophosphatidic acid receptor-1 enhances the induction of matrix metalloproteinase-2.

1 reference

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21 January 2018

B103 neuroblastoma cells predominantly express endothelin ET(B) receptor; effects of extracellular Ca(2+) influx on endothelin-1-induced mitogenesis

1 reference

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21 January 2018

Mice lacking adenylyl cyclase-5 cope badly with repeated restraint stress.

1 reference

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21 January 2018

Mice lacking adenylyl cyclase type 5 (AC5) show increased ethanol consumption and reduced ethanol sensitivity

1 reference

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Selective cytostatic and neurotoxic effects of avermectins and activation of the GABAalpha receptors.

1 reference

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Forskolin: a specific stimulator of adenylyl cyclase or a diterpene with multiple sites of action?

1 reference

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Nuclear apoptosis detection by flow cytometry: influence of endogenous endonucleases

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Adenylyl cyclase co-distribution with the CaBPs, calbindin-D28 and calretinin, varies with cell type: assessment with the fluorescent dye, BODIPY forskolin, in enteric ganglia

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0759-6

21 January 2018

Complex changes in ecto-nucleoside 5'-triphosphate diphosphohydrolase expression in hypoxanthine phosphoribosyl transferase deficiency

1 reference

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Hypoxanthine impairs morphogenesis and enhances proliferation of a neuroblastoma model of Lesch Nyhan syndrome

1 reference

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Purinergic signaling in human pluripotent stem cells is regulated by the housekeeping gene encoding hypoxanthine guanine phosphoribosyltransferase

1 reference

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Regulation of forskolin interactions with type I, II, V, and VI adenylyl cyclases by Gs alpha

1 reference

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21 January 2018

Effects of age and spatial learning on adenylyl cyclase mRNA expression in the mouse hippocampus.

1 reference

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21 January 2018

Different roles for Gi and Go proteins in modulation of adenylyl cyclase type-2 activity

1 reference

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21 January 2018

Dexamethasone-induced Ras protein 1 negatively regulates protein kinase C delta: implications for adenylyl cyclase 2 signaling

1 reference

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Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation.

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The recognition of Lesch-Nyhan syndrome as an inborn error of purine metabolism

2 references

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https://pubmed.ncbi.nlm.nih.gov/22552731

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Choreographing the adenylyl cyclase signalosome: sorting out the partners and the steps

1 reference

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Distinct characteristics of the basal activities of adenylyl cyclases 2 and 6.

1 reference

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Capturing adenylyl cyclases as potential drug targets

1 reference

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Decreased GTP-stimulated adenylyl cyclase activity in HPRT-deficient human and mouse fibroblast and rat B103 neuroblastoma cell membranes

1 reference

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Altered membrane NTPase activity in Lesch-Nyhan disease fibroblasts: comparison with HPRT knockout mice and HPRT-deficient cell lines

1 reference

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21 January 2018

Activation and inhibition of adenylyl cyclase isoforms by forskolin analogs.

1 reference

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Physiological roles for G protein-regulated adenylyl cyclase isoforms: insights from knockout and overexpression studies

1 reference

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Clonal cell lines from the rat central nervous system.

1 reference

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21 January 2018

Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0759-6

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Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors

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1 reference

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A human neuronal tissue culture model for Lesch-Nyhan disease

1 reference

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Tissue-specific aberrations of gene expression in HPRT-deficient mice: functional complexity in a monogenic disease?

1 reference

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21 January 2018

Isoforms of mammalian adenylyl cyclase: multiplicities of signaling

1 reference

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Protein tyrosine phosphatase receptor type Z is involved in hippocampus-dependent memory formation through dephosphorylation at Y1105 on p190 RhoGAP

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Update on the phenotypic spectrum of Lesch-Nyhan disease and its attenuated variants

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Differential expression of adenylyl cyclase subtypes in human cardiovascular system

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Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22552731

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Differential expression of type I, II, and V adenylyl cyclase gene in the postnatal developing rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22552731

12 December 2020

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Up-regulation of type II adenylyl cyclase mRNA in kindling model of epilepsy in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22552731

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inferred from PubMed ID database lookup

Pharmacological characterization of adenylyl cyclase isoforms in rabbit kidney membranes

1 reference

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inferred from PubMed ID database lookup

Inhibition of AC-II activity following chronic agonist exposure is modulated by phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22552731

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Functional analysis of brain dopamine systems in a genetic mouse model of Lesch-Nyhan syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/22552731

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22552731

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Characterization of the alterations in purine nucleotide metabolism in hypoxanthine-guanine phosphoribosyltransferase-deficient rat neuroma cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/22552731

12 December 2020

based on heuristic

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PACAP-38 induces neuronal differentiation of human SH-SY5Y neuroblastoma cells via cAMP-mediated activation of ERK and p38 MAP kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/22552731

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inferred from PubMed ID database lookup

Impaired D2 dopamine receptor function in mice lacking type 5 adenylyl cyclase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22552731

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based on heuristic

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Stimulation of adenylate cyclase by water-soluble analogues of forskolin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22552731

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00210-012-0759-6

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

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