(Q39360659)

11 September 2017

Phosphodiesterase-4 promotes proliferation and angiogenesis of lung cancer by crosstalk with HIF. (English)

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11 September 2017

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F Grimminger

10

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Thomas Braun

object named as

T Braun

9

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Werner Seeger

object named as

W Seeger

11

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author name string

S S Pullamsetti

1

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11 September 2017

G A Banat

2

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11 September 2017

A Schmall

3

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11 September 2017

M Szibor

4

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11 September 2017

D Pomagruk

5

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11 September 2017

J Hänze

6

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11 September 2017

E Kolosionek

7

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11 September 2017

J Wilhelm

8

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11 September 2017

R T Schermuly

12

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11 September 2017

R Savai

13

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11 September 2017

language of work or name

English

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publication date

23 April 2012

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11 September 2017

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11 September 2017

32

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11 September 2017

9

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11 September 2017

1121-1134

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https://scigraph.springernature.com/pub.10.1038/onc.2012.136

11 September 2017

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cites work

Cancer statistics, 2009

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Targeted therapies in the treatment of advanced/metastatic NSCLC.

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Recent developments of targeted therapies in the treatment of non-small cell lung cancer

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Epinephrine inhibits invasion of oral squamous carcinoma cells by modulating intracellular cAMP.

21 January 2018

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Role of prostaglandin E2 receptors in migration of murine and human breast cancer cells.

21 January 2018

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Chemoresistant KM12C colon cancer cells are addicted to low cyclic AMP levels in a phosphodiesterase 4-regulated compartment via effects on phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.136

Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.136

Cyclic nucleotide phosphodiesterase profiling reveals increased expression of phosphodiesterase 7B in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.136

Induction of apoptosis by an inhibitor of cAMP-specific PDE in malignant murine carcinoma cells overexpressing PDE activity in comparison to their nonmalignant counterparts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.136

Overview of PDEs and their regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.136

Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.136

Cyclic AMP-specific PDE4 phosphodiesterases as critical components of cyclic AMP signaling.

21 January 2018

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Cyclic 3',5'-nucleotide phosphodiesterases: potential targets for anticancer therapy

21 January 2018

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Antiproliferative effects of CC-8062 and CC-8075 in pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.136

Cyclic AMP specific phosphodiesterase activity and colon cancer cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.136

Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.136

Cyclic nucleotide phosphodiesterases as targets for treatment of haematological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.136

Hypoxia--a key regulatory factor in tumour growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.136

Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia-inducible factor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.136

Expression and activity of phosphodiesterase isoforms during epithelial mesenchymal transition: the role of phosphodiesterase 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.136

Interactions between hypoxia and epidermal growth factor receptor in non-small-cell lung cancer

21 January 2018

1 reference

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Prognostic significance of hypoxia-inducible factor-1alpha, TWIST1 and Snail expression in resectable non-small cell lung cancer

21 January 2018

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Integration of oxygen signaling at the consensus HRE.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.136

Hypoxia-induced remodelling of PDE4 isoform expression and cAMP handling in human pulmonary artery smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.136

Functional characterization of phosphodiesterases 4 in the rat carotid body: effect of oxygen concentrations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.136

The type IV phosphodiesterase inhibitor rolipram induces expression of the cell cycle inhibitors p21(Cip1) and p27(Kip1), resulting in growth inhibition, increased differentiation, and subsequent apoptosis of malignant A-172 glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.136

Inhibition of PDE4 phosphodiesterase activity induces growth suppression, apoptosis, glucocorticoid sensitivity, p53, and p21(WAF1/CIP1) proteins in human acute lymphoblastic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.136

Phosphodiesterase-4 inhibitors for asthma and chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.136

HIF-1 alpha signaling is augmented during intermittent hypoxia by induction of the Nrf2 pathway in NOX1-expressing adenocarcinoma A549 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.136

Prognostic significance of platelet and microvessel counts in operable non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.136

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.136

1 reference

Dimensions Publication ID

11 September 2017

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1 reference