(Q39361013)

11 September 2017

title

Activation of HIF-1 by metallothionein contributes to cardiac protection in the diabetic heart (English)

1 reference

11 September 2017

Wanli Xue

1

1 reference

11 September 2017

Yanlong Liu

2

1 reference

11 September 2017

Jingchan Zhao

3

1 reference

11 September 2017

Lu Cai

4

1 reference

11 September 2017

Xiaokun Li

5

1 reference

11 September 2017

Wenke Feng

6

1 reference

11 September 2017

publication date

20 April 2012

1 reference

American Journal of Physiology Heart and Circulatory Physiology

11 September 2017

published in

1 reference

11 September 2017

volume

302

1 reference

11 September 2017

issue

12

1 reference

11 September 2017

page(s)

H2528-35

1 reference

Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart.

11 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Inhibition of superoxide generation and associated nitrosative damage is involved in metallothionein prevention of diabetic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Hyperglycemia regulates hypoxia-inducible factor-1alpha protein stability and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Decreasing intracellular superoxide corrects defective ischemia-induced new vessel formation in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Ang-1 gene therapy inhibits hypoxia-inducible factor-1alpha (HIF-1alpha)-prolyl-4-hydroxylase-2, stabilizes HIF-1alpha expression, and normalizes immature vasculature in db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Metallothionein: the multipurpose protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Carbonylation of glycolytic proteins is a key response to drug-induced oxidative stress and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Metallothionein rescues hypoxia-inducible factor-1 transcriptional activity in cardiomyocytes under diabetic conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Hyperglycemia activates p53 and p53-regulated genes leading to myocyte cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Regulation of angiogenic growth factor expression by hypoxia, transition metals, and chelating agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Metabolism, hypoxia and the diabetic heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Metallothionein-III induces HIF-1alpha-mediated VEGF expression in brain endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Metallothionein is upregulated by hypoxia and stabilizes hypoxia-inducible factor in the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Impaired cardiac efficiency and increased fatty acid oxidation in insulin-resistant ob/ob mouse hearts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Metallothionein induction by hypoxia involves cooperative interactions between metal-responsive transcription factor-1 and hypoxia-inducible transcription factor-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

The metal-responsive transcription factor-1 contributes to HIF-1 activation during hypoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Regulation of Hexokinase II Gene Transcription and Glucose Phosphorylation by Catecholamines, Cyclic AMP, and Insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Metallothionein alleviates glutathione depletion-induced oxidative cardiomyopathy in murine hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Adenoviral transfer of HIF-1alpha enhances vascular responses to critical limb ischemia in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Vascular endothelial growth factor transcriptional activation is mediated by hypoxia-inducible factor 1alpha, HDM2, and p70S6K1 in response to phosphatidylinositol 3-kinase/AKT signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

HIF-1alpha dysfunction in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Regulation of vascular endothelial growth factor expression by advanced glycation end products

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Cardiac metallothionein induction plays the major role in the prevention of diabetic cardiomyopathy by zinc supplementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Cardiac phosphatase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase increases glycolysis, hypertrophy, and myocyte resistance to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Inactivation of GSK-3beta by metallothionein prevents diabetes-related changes in cardiac energy metabolism, inflammation, nitrosative damage, and remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Cardiac-specific overexpression of HIF-1{alpha} prevents deterioration of glycolytic pathway and cardiac remodeling in streptozotocin-induced diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Stable overexpression of human metallothionein-IIA in a heart-derived cell line confers oxidative protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Metallothionein prevents diabetes-induced deficits in cardiomyocytes by inhibiting reactive oxygen species production

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

Metallothionein suppresses angiotensin II-induced nicotinamide adenine dinucleotide phosphate oxidase activation, nitrosative stress, apoptosis, and pathological remodeling in the diabetic heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00850.2011

10.1152/AJPHEART.00850.2011

21 January 2018

Identifiers

DOI

1 reference

11 September 2017

1 reference