(Q39894511)

15 September 2017

title

Metallothionein is upregulated by hypoxia and stabilizes hypoxia-inducible factor in the kidney (English)

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15 September 2017

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5

Hiroyuki Aburatani

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15 September 2017

Ichiro Kojima

1

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15 September 2017

Tetsuhiro Tanaka

2

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15 September 2017

Reiko Inagi

3

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15 September 2017

Hiroshi Nishi

4

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15 September 2017

Hideki Kato

6

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15 September 2017

Toshio Miyata

7

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15 September 2017

Toshiro Fujita

8

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15 September 2017

Masaomi Nangaku

9

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15 September 2017

language of work or name

English

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publication date

1 October 2008

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15 September 2017

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15 September 2017

volume

75

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15 September 2017

issue

3

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15 September 2017

page(s)

268-277

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Intrarenal oxygenation in chronic renal failure

15 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Chronic hypoxia and tubulointerstitial injury: a final common pathway to end-stage renal failure

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7 January 2021

Cobalt promotes angiogenesis via hypoxia-inducible factor and protects tubulointerstitium in the remnant kidney model.

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https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Evidence of tubular hypoxia in the early phase in the remnant kidney model

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https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Induction of protective genes by cobalt ameliorates tubulointerstitial injury in the progressive Thy1 nephritis

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7 January 2021

Hypoperfusion of peritubular capillaries induces chronic hypoxia before progression of tubulointerstitial injury in a progressive model of rat glomerulonephritis

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7 January 2021

Hypoxia in renal disease with proteinuria and/or glomerular hypertension

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7 January 2021

Renoprotective properties of angiotensin receptor blockers beyond blood pressure lowering

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7 January 2021

Hypoxia-inducible factor modulates tubular cell survival in cisplatin nephrotoxicity

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7 January 2021

Hypoxia and expression of hypoxia-inducible factor in the aging kidney.

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7 January 2021

Blood oxygen level-dependent measurement of acute intra-renal ischemia.

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7 January 2021

Ischemic and nephrotoxic acute renal failure are distinguished by their broad transcriptomic responses

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7 January 2021

Monitoring changes in gene expression in renal ischemia-reperfusion in the rat.

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7 January 2021

Identification of thrombospondin 1 (TSP-1) as a novel mediator of cell injury in kidney ischemia

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7 January 2021

Modification of the transcriptomic response to renal ischemia/reperfusion injury by lipoxin analog.

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7 January 2021

Differential gene expression following early renal ischemia/reperfusion.

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https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

The role of HIF-1 alpha in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia

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7 January 2021

Experimental chronic renal ischemia: morphologic and immunologic studies

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7 January 2021

Chronic hypoxia aggravates renal injury via suppression of Cu/Zn-SOD: a proteomic analysis.

1 reference

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7 January 2021

Transdifferentiation of cultured tubular cells induced by hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Blockade of calcium influx through L-type calcium channels attenuates mitochondrial injury and apoptosis in hypoxic renal tubular cells

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https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Hypoxia-induced apoptosis in cultured glomerular endothelial cells: involvement of mitochondrial pathways.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Hypoxia induces apoptosis in SV40-immortalized rat proximal tubular cells through the mitochondrial pathways, devoid of HIF1-mediated upregulation of Bax.

1 reference

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7 January 2021

Hypoxia stimulates proximal tubular cell matrix production via a TGF-beta1-independent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Hypoxia promotes fibrogenesis in human renal fibroblasts

1 reference

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7 January 2021

Differential expression of metallothionein 1 and 2 isoforms in breast cancer lines with different invasive potential: identification of a novel nonsilent metallothionein-1H mutant variant.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Metallothionein immunoreactivity in the liver and kidney of copper injected rats

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https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Regulation, Linkage, and Sequence of Mouse Metallothionein I and II Genes

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Oxidative stress activates metal-responsive transcription factor-1 binding activity. Occupancy in vivo of metal response elements in the metallothionein-I gene promoter

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Metallothionein protects islets from hypoxia and extends islet graft survival by scavenging most kinds of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Antiapoptotic Effect and Inhibition of Ischemia/Reperfusion-Induced Myocardial Injury in Metallothionein-Overexpressing Transgenic Mice

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Inhibition of hypoxia/reoxygenation-induced apoptosis in metallothionein-overexpressing cardiomyocytes

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Current understanding of HIF in renal disease

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Hypoxia and the HIF system in kidney disease

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Metallothionein rescues hypoxia-inducible factor-1 transcriptional activity in cardiomyocytes under diabetic conditions

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Effect of altered redox states on expression and DNA-binding activity of hypoxia-inducible factor 1.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Redox regulation of HIF-1alpha levels and HO-1 expression in renal medullary interstitial cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

A Fenton reaction at the endoplasmic reticulum is involved in the redox control of hypoxia-inducible gene expression

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Effect of desferrioxamine and metals on the hydroxylases in the oxygen sensing pathway

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Identification of metallothionein receptors in human astrocytes

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Megalin mediates renal uptake of heavy metal metallothionein complexes.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Lipid raft-dependent endocytosis of metallothionein in HepG2 cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

TORward AKTually useful mouse models

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

In vitro study of HIF-1 activation and VEGF release by bFGF in the T47D breast cancer cell line under normoxic conditions: involvement of PI-3K/Akt and MEK1/ERK pathways.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Intracellular zinc release, 12-lipoxygenase activation and MAPK dependent neuronal and oligodendroglial death

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

The requirement of extracellular signal-related protein kinase pathway in the activation of hypoxia inducible factor 1 alpha in the developing rat brain after hypoxia-ischemia

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

High glucose blunts vascular endothelial growth factor response to hypoxia via the oxidative stress-regulated hypoxia-inducible factor/hypoxia-responsible element pathway

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Induction of renoprotective gene expression by cobalt ameliorates ischemic injury of the kidney in rats

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Effect of zinc deficiency on the mRNA expression pattern in liver and jejunum of adult rats: monitoring gene expression using cDNA microarrays combined with real-time RT-PCR.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.488

7 January 2021

Identifiers

DOI

10.1038/KI.2008.488

1 reference

Dimensions Publication ID

15 September 2017

1018164523

0 references

1 reference