(Q39366472)

English

Differential association of receptor-Gβγ complexes with β-arrestin2 determines recycling bias and potential for tolerance of δ opioid receptor agonists

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

11 September 2017

Differential association of receptor-Gβγ complexes with β-arrestin2 determines recycling bias and potential for tolerance of δ opioid receptor agonists (English)

1 reference

Europe PubMed Central

11 September 2017

0 references

1 reference

based on heuristic

inferred from title

author name string

Nicolas Audet

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6620903&resulttype=core&format=json

15 May 2020

Iness Charfi

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6620903&resulttype=core&format=json

15 May 2020

Ouissame Mnie-Filali

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6620903&resulttype=core&format=json

15 May 2020

Mohammad Amraei

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6620903&resulttype=core&format=json

15 May 2020

Anne-Julie Chabot-Doré

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6620903&resulttype=core&format=json

15 May 2020

Magali Millecamps

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6620903&resulttype=core&format=json

15 May 2020

Laura S Stone

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6620903&resulttype=core&format=json

15 May 2020

Graciela Pineyro

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6620903&resulttype=core&format=json

15 May 2020

language of work or name

0 references

publication date

1 April 2012

1 reference

Europe PubMed Central

11 September 2017

Journal of Neuroscience

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6620903&resulttype=core&format=json

15 May 2020

32

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6620903&resulttype=core&format=json

15 May 2020

14

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6620903&resulttype=core&format=json

15 May 2020

4827-4840

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6620903&resulttype=core&format=json

15 May 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6620903/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Cellular trafficking of G protein-coupled receptor/beta-arrestin endocytic complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced morphine analgesia in mice lacking beta-arrestin 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recycling and resensitization of delta opioid receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arrestin binding to the G protein-coupled N-formyl peptide receptor is regulated by the conserved "DRY" sequence

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spared nerve injury: an animal model of persistent peripheral neuropathic pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hierarchical phosphorylation of delta-opioid receptor regulates agonist-induced receptor desensitization and internalization

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heterodimerization of mu and delta opioid receptors: A role in opiate synergy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping of calmodulin and Gbetagamma binding domains within the C-terminal region of the metabotropic glutamate receptor 7A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Short-term inverse-agonist treatment induces reciprocal changes in delta-opioid agonist and inverse-agonist binding capacity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

mu-Opioid receptors desensitize less rapidly than delta-opioid receptors due to less efficient activation of arrestin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of postendocytic sorting of G protein-coupled receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonist-specific down-regulation of the human delta-opioid receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonist-induced formation of opioid receptor-G protein-coupled receptor kinase (GRK)-G beta gamma complex on membrane is required for GRK2 function in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spared nerve injury model of neuropathic pain in the mouse: a behavioral and anatomic analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a novel endocytic recycling signal in the D1 dopamine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relative opioid efficacy is determined by the complements of the G protein-coupled receptor desensitization machinery

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Internalization and Src activity regulate the time course of ERK activation by delta opioid receptor ligands.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Real-time monitoring of receptor and G-protein interactions in living cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A docking site for G protein βγ subunits on the parathyroid hormone 1 receptor supports signaling through multiple pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-arrestin1 and beta-arrestin2 are differentially required for phosphorylation-dependent and -independent internalization of delta-opioid receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The differential engagement of arrestin surface charges by the various functional forms of the receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathic pain is enhanced in delta-opioid receptor knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[D-Pen2,4'-125I-Phe4,D-Pen5]enkephalin: a selective high affinity radioligand for delta opioid receptors with exceptional specific activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous activation of the delta opioid receptor (deltaOR)/sensory neuron-specific receptor-4 (SNSR-4) hetero-oligomer by the mixed bivalent agonist bovine adrenal medulla peptide 22 activates SNSR-4 but inhibits deltaOR signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Knockin mice expressing fluorescent delta-opioid receptors uncover G protein-coupled receptor dynamics in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional Selectivity and Classical Concepts of Quantitative Pharmacology

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Probing the activation-promoted structural rearrangements in preassembled receptor-G protein complexes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trafficking of delta-opioid receptors and other G-protein-coupled receptors: implications for pain and analgesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Real-time analysis of agonist-induced activation of protease-activated receptor 1/Galphai1 protein complex measured by bioluminescence resonance energy transfer in living cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of the delta-opioid receptor regulates its beta-arrestins selectivity and subsequent receptor internalization and adenylyl cyclase desensitization

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in G protein-coupled receptor sorting protein affinity regulate postendocytic targeting of G protein-coupled receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unraveling G protein-coupled receptor endocytosis pathways using real-time monitoring of agonist-promoted interaction between beta-arrestins and AP-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional selectivity through protean and biased agonism: who steers the ship?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of mu opioid receptor desensitization and endocytosis in morphine tolerance and dependence

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphine-induced receptor endocytosis in a novel knockin mouse reduces tolerance and dependence

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Src promotes delta opioid receptor (DOR) desensitization by interfering with receptor recycling

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bioluminescence resonance energy transfer assays reveal ligand-specific conformational changes within preformed signaling complexes containing delta-opioid receptors and heterotrimeric G proteins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular neuroadaptations to chronic opioids: tolerance, withdrawal and addiction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Post-endocytic fates of delta-opioid receptor are regulated by GRK2-mediated receptor phosphorylation and distinct beta-arrestin isoforms

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological characterization of membrane-expressed human trace amine-associated receptor 1 (TAAR1) by a bioluminescence resonance energy transfer cAMP biosensor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential activation and trafficking of micro-opioid receptors in brain slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Culture of postnatal mesencephalic dopamine neurons on an astrocyte monolayer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Arrestin1 interacts with the G-protein subunits beta1gamma2 and promotes beta1gamma2-dependent Akt signalling for NF-kappaB activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential noxious and motor tolerance of chronic delta opioid receptor agonists in rodents

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G protein independent phosphorylation and internalization of the delta-opioid receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo delta opioid receptor internalization controls behavioral effects of agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubiquitination regulates proteolytic processing of G protein-coupled receptors after their sorting to lysosomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional selectivity of natural and synthetic prostaglandin EP4 receptor ligands.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Introduction: Recommendations for the diagnosis, assessment, and treatment of neuropathic pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dosing protocol and analgesic efficacy determine opioid tolerance in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphine-like opiates selectively antagonize receptor-arrestin interactions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of peripheral endothelin receptors in an animal model of complex regional pain syndrome type 1 (CRPS-I)

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ligand-directed trafficking of the δ-opioid receptor in vivo: two paths toward analgesic tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic ablation of delta opioid receptors in nociceptive sensory neurons increases chronic pain and abolishes opioid analgesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular morphine tolerance produced by βarrestin-2-dependent impairment of μ-opioid receptor resensitization.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of opioid receptor signalling: implications for the development of analgesic tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Using BRET to detect ligand-specific conformational changes in preformed signalling complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrathecal morphine in mice: a new technique

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative assessment of tactile allodynia in the rat paw

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-activity relationships for SNC80 and related compounds at cloned human delta and mu opioid receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of quenching of phototransduction. Binding competition between arrestin and transducin for phosphorhodopsin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a signaling pathway involved in calcium regulation of BDNF expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22492038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.3734-11.2012

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6620903&resulttype=core&format=json

15 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6620903&resulttype=core&format=json

15 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6620903&resulttype=core&format=json

15 May 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q39366472&oldid=1823089872"