(Q39371166)

English

Kynurenine Pathway Pathologies: do Nicotinamide and Other Pathway Co-Factors have a Therapeutic Role in Reduction of Symptom Severity, Including Chronic Fatigue Syndrome (CFS) and Fibromyalgia (FM)

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

Kynurenine Pathway Pathologies: do Nicotinamide and Other Pathway Co-Factors have a Therapeutic Role in Reduction of Symptom Severity, Including Chronic Fatigue Syndrome (CFS) and Fibromyalgia (FM) (English)

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

0 references

chronic fatigue syndrome

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Adele Blankfield

1

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

publication date

21 July 2013

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

International Journal of Tryptophan Research

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

6

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

Suppl 1

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

39-45

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Protein energy malnutrition impairs homeostatic proliferation of memory CD8 T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Kynurenine pathway Hypothesis: The nature of the chronic Fatigue syndrome (cFs) Revisited

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Effects of Kynurenine Pathway Inhibition on NAD Metabolism and Cell Viability in Human Primary Astrocytes and Neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Effects of Kynurenine Pathway Metabolites on Intracellular NAD Synthesis and Cell Death in Human Primary Astrocytes and Neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Kynurenine pathway metabolites in humans: disease and healthy States

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Malnutrition and clinical outcome in urological patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Role of infection and neurologic dysfunction in chronic fatigue syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Increased protein-energy intake promotes anabolism in critically ill infants with viral bronchiolitis: a double-blind randomised controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Role of nicotinamide in DNA damage, mutagenesis, and DNA repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Intestinal antimicrobial gene expression: impact of micronutrients in malnourished adults during a randomized trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Endemic pellagra in northern Portugal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Adult starvation and disease-related malnutrition: a proposal for etiology-based diagnosis in the clinical practice setting from the International Consensus Guideline Committee.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Pathophysiological changes that affect drug disposition in protein-energy malnourished children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Niacin status and treatment-related leukemogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Cutaneous lesions and vitamin B12 deficiency: an often-forgotten link

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

NAD+ and vitamin B3: from metabolism to therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Post-infective and chronic fatigue syndromes precipitated by viral and non-viral pathogens: prospective cohort study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Micronutrients in childhood and the influence of subclinical inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Monitoring tryptophan metabolism in chronic immune activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Comparison of oral nicotinamide adenine dinucleotide (NADH) versus conventional therapy for chronic fatigue syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Tryptophan depletion and HIV infection: a metabolic link to pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Multiple co-infections (Mycoplasma, Chlamydia, human herpes virus-6) in blood of chronic fatigue syndrome patients: association with signs and symptoms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Nicotinamide: an oral antimicrobial agent with activity against both Mycobacterium tuberculosis and human immunodeficiency virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Circulating tumour necrosis factor-alpha and interferon-gamma are detectable during acute and convalescent parvovirus B19 infection and are associated with prolonged and chronic fatigue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Increased plasma tryptophan in HIV-infected patients treated with pharmacologic doses of nicotinamide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Kynurenines in the CNS: from endogenous obscurity to therapeutic importance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Nutritional strategies for treating chronic fatigue syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Increased concentrations of homocysteine in the cerebrospinal fluid in patients with fibromyalgia and chronic fatigue syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Physical illness manifesting as psychiatric disease. II. Analysis of a state hospital inpatient population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Biochemistry of tryptophan in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Crohn's disease presenting as anorexia nervosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Postviral fatigue syndrome: time for a new approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Abnormal illness behaviours and their treatments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Neurasthenia in the 1980s: chronic mononucleosis, chronic fatigue syndrome, and anxiety and depressive disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Implications of interferon-induced tryptophan catabolism in cancer, auto-immune diseases and AIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

11 September 2017

Neurological complications of acquired cobalamin deficiency: clinical aspects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

25 September 2017

Acute psychosis: a presentation of cyanocobalamin deficiency megaloblastic anemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

25 September 2017

Studies of tryptophan metabolism in protein-energy malnutrition (PEM)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

25 September 2017

Does B12 deficiency lead to lack of treatment response to conventional antidepressants?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

15 June 2018

Inhibition of the kynurenine-NAD+ pathway leads to energy failure and exacerbates apoptosis in pneumococcal meningitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

15 June 2018

Comparison between tryptophan methoxyindole and kynurenine metabolic pathways in normal and preterm neonates and in neonates with acute fetal distress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

15 June 2018

Plasma tryptophan and other amino acids in pellagra.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

15 June 2018

Somatization: medicine's unsolved problem

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

15 June 2018

Hereditary defect of cobalamin metabolism (cblG mutation) presenting as a neurologic disorder in adulthood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

15 June 2018

Physical illness and depression: the effects of acute physical illness on the mental state of psychiatric inpatients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

15 June 2018

A Brief Historic Overview of Clinical Disorders Associated with Tryptophan: The Relevance to Chronic Fatigue Syndrome (CFS) and Fibromyalgia (FM).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

21 August 2018

Increased d-lactic Acid intestinal bacteria in patients with chronic fatigue syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

21 August 2018

Pellagra and the blues song 'Cornbread, meat and black molasses'.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

21 August 2018

Tryptophan catabolism in females with irritable bowel syndrome: relationship to interferon-gamma, severity of symptoms and psychiatric co-morbidity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

21 August 2018

Whole blood NAD and NADP concentrations are not depressed in subjects with clinical pellagra

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

21 August 2018

Double-blind, multicenter trial comparing acetyl l-carnitine with placebo in the treatment of fibromyalgia patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

21 August 2018

Cobalamin deficiency with and without neurologic abnormalities: differences in homocysteine and methionine metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

21 August 2018

Effective antiretroviral therapy reduces degradation of tryptophan in patients with HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

21 August 2018

Whey protein rich in alpha-lactalbumin increases the ratio of plasma tryptophan to the sum of the other large neutral amino acids and improves cognitive performance in stress-vulnerable subjects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

21 August 2018

Plasma urea appearance rate is lower when children with kwashiorkor and infection are fed egg white-tryptophan rather than milk protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

21 August 2018

Autonomic dysfunction and orthostatic hypotention caused by vitamin B12 deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729338

21 August 2018

Inflammatory mediators in children with protein-energy malnutrition

1 reference

https://pubmed.ncbi.nlm.nih.gov/23922501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Does the Illness Behavior Questionnaire measure abnormal illness behavior?

1 reference

https://pubmed.ncbi.nlm.nih.gov/23922501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nutritional deficiencies in patients receiving cancer chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23922501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D-lactic acidosis: pathologic consequence of saprophytism

1 reference

https://pubmed.ncbi.nlm.nih.gov/23922501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunomodulation by vitamin B12: augmentation of CD8+ T lymphocytes and natural killer (NK) cell activity in vitamin B12-deficient patients by methyl-B12 treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/23922501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in plasma amino acid concentrations in response to HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/23922501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An investigation of patients presenting with multiple physical complaints using the illness behaviour questionnaire

1 reference

https://pubmed.ncbi.nlm.nih.gov/23922501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of psychological and biological factors in postinfective gut dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/23922501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibody to parvovirus B19 nonstructural protein is associated with chronic arthralgia in patients with chronic fatigue syndrome/myalgic encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23922501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide blocks proliferation and induces apoptosis of chronic lymphocytic leukemia cells through activation of the p53/miR-34a/SIRT1 tumor suppressor network

1 reference

https://pubmed.ncbi.nlm.nih.gov/23922501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Water-soluble vitamins in cancer patients on parenteral nutrition: a prospective study

1 reference

https://pubmed.ncbi.nlm.nih.gov/23922501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma amino acid patterns in alcoholic pellagra patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/23922501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation is associated with increased energy expenditure in patients with chronic kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23922501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A subset of fibromyalgia patients have findings suggestive of chronic inflammatory demyelinating polyneuropathy and appear to respond to IVIg

1 reference

https://pubmed.ncbi.nlm.nih.gov/23922501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on tryptophan metabolism in protein-calorie malnutrition

1 reference

https://pubmed.ncbi.nlm.nih.gov/23922501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4137/IJTR.S11193

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

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