(Q39372689)

11 September 2017

title

MYC directs transcription of MCL1 and eIF4E genes to control sensitivity of gastric cancer cells toward HDAC inhibitors (English)

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Angelika Schnieke

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author name string

Wajana L Labisso

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Matthias Wirth

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Natasa Stojanovic

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Roland M Schmid

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Dieter Saur

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Günter Schneider

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publication date

15 April 2012

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volume

11

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issue

8

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page(s)

1593-1602

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The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

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cites work

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Histone deacetylases and cancer

21 January 2018

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Inhibitors of HDACs--effective drugs against cancer?

21 January 2018

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The clinical development of histone deacetylase inhibitors as targeted anticancer drugs

21 January 2018

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Rational therapeutic combinations with histone deacetylase inhibitors for the treatment of cancer

21 January 2018

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Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy.

21 January 2018

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HDAC expression and clinical prognosis in human malignancies

21 January 2018

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Expression profile of histone deacetylase 1 in gastric cancer tissues.

21 January 2018

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Increased expression of histone deacetylase 2 is found in human gastric cancer.

21 January 2018

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Association of patterns of class I histone deacetylase expression with patient prognosis in gastric cancer: a retrospective analysis.

21 January 2018

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Histone deacetylase (HDAC) 1 and 2 expression and chemotherapy in gastric cancer

21 January 2018

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Contribution of reactivated RUNX3 to inhibition of gastric cancer cell growth following suberoylanilide hydroxamic acid (vorinostat) treatment

21 January 2018

1 reference

The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy

21 January 2018

1 reference

Enhancement of sensitivity of urinary bladder tumor cells to cisplatin by c-myc antisense oligonucleotide

21 January 2018

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c-MYC suppresses BIN1 to release poly(ADP-ribose) polymerase 1: a mechanism by which cancer cells acquire cisplatin resistance

21 January 2018

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MYC-dependent regulation and prognostic role of CIP2A in gastric cancer.

21 January 2018

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Low molecular weight inhibitors of Myc-Max interaction and function

21 January 2018

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Increased expression of eukaryotic translation initiation factors eIF-4E and eIF-2 alpha in response to growth induction by c-myc

21 January 2018

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An essential E box in the promoter of the gene encoding the mRNA cap-binding protein (eukaryotic initiation factor 4E) is a target for activation by c-myc

21 January 2018

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c-Myc and eIF4F are components of a feedforward loop that links transcription and translation

21 January 2018

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Histone deacetylase inhibitors: a new class of immunosuppressors targeting a novel signal pathway essential for CD154 expression

21 January 2018

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The polycomb group protein BMI1 is a transcriptional target of HDAC inhibitors.

21 January 2018

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Combining histone deacetylase inhibitor vorinostat with aurora kinase inhibitors enhances lymphoma cell killing with repression of c-Myc, hTERT, and microRNA levels

21 January 2018

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Enhancing the apoptotic and therapeutic effects of HDAC inhibitors

21 January 2018

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Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma

21 January 2018

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Expression of Mcl-1 and p53 proteins predicts the survival of patients with T3 gastric carcinoma

21 January 2018

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Mcl-1 is a relevant molecular target for antisense oligonucleotide strategies in gastric cancer cells

21 January 2018

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Modulation of apoptosis by endogenous Bcl-xL expression in MKN-45 human gastric cancer cells

21 January 2018

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Over-expression of bcl-xL gene in human gastric adenomas and carcinomas.

21 January 2018

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A gene expression signature of acquired chemoresistance to cisplatin and fluorouracil combination chemotherapy in gastric cancer patients

21 January 2018

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Three-gene predictor of clinical outcome for gastric cancer patients treated with chemotherapy

21 January 2018

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21 January 2018

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Modelling Myc inhibition as a cancer therapy

21 January 2018

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Therapeutic Targeting of Myc.

21 January 2018

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MYC and gastric adenocarcinoma carcinogenesis

21 January 2018

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Genomic targets of the human c-Myc protein

21 January 2018

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Regulation of translation initiation in eukaryotes: mechanisms and biological targets

21 January 2018

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Cap in hand: targeting eIF4E.

21 January 2018

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Targeting the eukaryotic translation initiation factor 4E for cancer therapy

21 January 2018

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Expression of eukaryotic initiation factor 4E in gastric adenocarcinoma and its association with clinical outcome.

21 January 2018

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eIF4E knockdown decreases breast cancer cell growth without activating Akt signaling

21 January 2018

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Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression

21 January 2018

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Schedule-dependent synergy of histone deacetylase inhibitors with DNA damaging agents in small cell lung cancer

21 January 2018

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The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy

21 January 2018

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HDAC2 mediates therapeutic resistance of pancreatic cancer cells via the BH3-only protein NOXA.

21 January 2018

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A simple and cost-effective method to transfect small interfering RNAs into pancreatic cancer cell lines using polyethylenimine

21 January 2018

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A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer.

21 January 2018

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Chromatin immunoprecipitation (ChIP) coupled to detection by quantitative real-time PCR to study transcription factor binding to DNA in Caenorhabditis elegans.

21 January 2018

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21 January 2018

Identifiers

DOI

10.4161/CC.20008

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11 September 2017

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