(Q39378063)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426229%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426229%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426229%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Diana Jurk

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426229%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Morgan Taschuk

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426229%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Joao F Passos

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426229%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author name string

Francisco D M Marques

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426229%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Clara Correia-Melo

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426229%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Timothy Hardy

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426229%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Agata Gackowska

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426229%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Rhys Anderson

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426229%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Jelena Mann

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426229%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

language of work or name

English

0 references

publication date

28 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426229%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426229%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426229%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

708

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426229%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported

26 January 2020

copyright license

start time

1 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3292717/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Feedback between p21 and reactive oxygen production is necessary for cell senescence

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Crosstalk between histone modifications during the DNA damage response.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

The longest telomeres: a general signature of adult stem cell compartments

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Cellular senescence: when bad things happen to good cells

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

A RAP1/TRF2 complex inhibits nonhomologous end-joining at human telomeric DNA ends

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Spreading of mammalian DNA-damage response factors studied by ChIP-chip at damaged telomeres

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

A telomeric repeat sequence adjacent to a DNA double-stranded break produces an anticheckpoint

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Shelterin: the protein complex that shapes and safeguards human telomeres

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Functional links between telomeres and proteins of the DNA-damage response

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Visualizing telomere dynamics in living mammalian cells using PNA probes

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

A DNA damage checkpoint response in telomere-initiated senescence

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

DNA damage foci at dysfunctional telomeres

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Telomere measurement by quantitative PCR

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhang

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Mammalian telomeres end in a large duplex loop

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

TRF2 Protects Human Telomeres from End-to-End Fusions

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Extension of life-span by introduction of telomerase into normal human cells

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

DNA damage and repair in telomeres: relation to aging

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Telomere length and replicative aging in human vascular tissues

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

DNA damage foci in mitosis are devoid of 53BP1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Site-specific DNA damage at the GGG sequence by UVA involves acceleration of telomere shortening

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Preferential accumulation of single-stranded regions in telomeres of human fibroblasts

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Adult-onset, short-term dietary restriction reduces cell senescence in mice.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Sequence-specific DNA cleavage by Fe2+-mediated fenton reactions has possible biological implications

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

Cellular senescence in aging primates.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3292717

The role of chondrocyte senescence in osteoarthritis

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22426229

12 December 2020

inferred from PubMed ID database lookup

Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22426229

12 December 2020

inferred from PubMed ID database lookup

DNA damage response and cellular senescence in tissues of aging mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22426229

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NCOMMS1708

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426229%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426229%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

PubMed publication ID

22426229

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426229%20AND%20SRC:MED&resulttype=core&format=json