(Q37030330)

17 August 2017

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation (English)

1 reference

Erratum: Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

17 August 2017

0 references

corrigendum / erratum

0 references

Marzia Fumagalli

1

0 references

Gabriele Bucci

Gabriele Bucci

7

0 references

Maria Pia Longhese

Maria Pia Longhese

12

0 references

Davide Cittaro

Davide Cittaro

Fabrizio d'Adda di Fagagna

5

0 references

13

Fabrizio d'Adda di Fagagna

1 reference

17 August 2017

Francesca Rossiello

2

1 reference

17 August 2017

Michela Clerici

3

1 reference

17 August 2017

Sara Barozzi

4

1 reference

17 August 2017

Jessica M Kaplunov

6

1 reference

17 August 2017

Miryana Dobreva

8

1 reference

17 August 2017

Valentina Matti

9

1 reference

17 August 2017

Christian M Beausejour

10

1 reference

17 August 2017

Utz Herbig

11

1 reference

17 August 2017

18 March 2012

1 reference

17 August 2017

1 reference

17 August 2017

14

1 reference

17 August 2017

4

1 reference

17 August 2017

355-365

1 reference

describes a project that uses

17 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3717580/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/ncb2466

0 references

cites work

Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Comparative biology of mammalian telomeres: hypotheses on ancestral states and the roles of telomeres in longevity determination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Positive feedback between p53 and TRF2 during telomere-damage signalling and cellular senescence.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

TRF2 and apollo cooperate with topoisomerase 2alpha to protect human telomeres from replicative damage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

TRF2/RAP1 and DNA-PK mediate a double protection against joining at telomeric ends

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Ionizing radiation-induced long-term expression of senescence markers in mice is independent of p53 and immune status

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Telomeres: protecting chromosomes against genome instability

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Fast and accurate long-read alignment with Burrows-Wheeler transform

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

The DNA-damage response in human biology and disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Cellular senescence: hot or what?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Activation of the cellular DNA damage response in the absence of DNA lesions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

An oncogene-induced DNA damage model for cancer development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Cellular senescence: when bad things happen to good cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Cellular senescence in cancer and aging

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

DNA repair is limiting for haematopoietic stem cells during ageing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

MRX-dependent DNA damage response to short telomeres

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

p53 mediates senescence-like arrest induced by chronic replicational stress

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

A RAP1/TRF2 complex inhibits nonhomologous end-joining at human telomeric DNA ends

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Spreading of mammalian DNA-damage response factors studied by ChIP-chip at damaged telomeres

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Positional stability of single double-strand breaks in mammalian cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Need telomere maintenance? Call 911

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Accumulation of senescent cells in mitotic tissue of aging primates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

A telomeric repeat sequence adjacent to a DNA double-stranded break produces an anticheckpoint

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

BRAFE600-associated senescence-like cell cycle arrest of human naevi

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Targeting the checkpoint kinases: chemosensitization versus chemoprotection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

A DNA damage checkpoint response in telomere-initiated senescence

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

DNA damage foci at dysfunctional telomeres

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Senescence, apoptosis and therapy--cutting the lifelines of cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Targeting assay to study the cis functions of human telomeric proteins: evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Preferential accumulation of single-stranded regions in telomeres of human fibroblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

TRF2 Protects Human Telomeres from End-to-End Fusions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G1 arrest

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Telomeres shorten during ageing of human fibroblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Tumour biology: senescence in premalignant tumours

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Cellular senescence in aging primates.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Oncogene-induced senescence as an initial barrier in lymphoma development

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Valproic acid alters chromatin structure by regulation of chromatin modulation proteins

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3717580

Exonuclease activity is required for sequence addition and Cdc13p loading at a de novo telomere

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22426077

12 December 2020

inferred from PubMed ID database lookup

Multiple pathways inhibit NHEJ at telomeres.

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCB2466

7 January 2021

inferred from DOI database lookup

Is cellular senescence an example of antagonistic pleiotropy?

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCB2466

7 January 2021

inferred from DOI database lookup

HIF1A signaling selectively supports proliferation of breast cancer in the brain

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCB2466

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NCB2466

1 reference

Dimensions Publication ID

17 August 2017

1031446853

0 references

Fatcat ID

release_h2wxyyenpra63jvbjm65lahtye

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/h2wxyyenpra63jvbjm65lahtye

24 November 2022

mapped directly with Wikidata item

1 reference

17 August 2017

PubMed publication ID

22426077

1 reference