(Q39378845)

11 September 2017

title

Overexpressed mutant optineurin(E50K) induces retinal ganglion cells apoptosis via the mitochondrial pathway (English)

1 reference

11 September 2017

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retinal ganglion cell

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Qingfeng Meng

1

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11 September 2017

Jia Lv

2

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11 September 2017

Hongyan Ge

3

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11 September 2017

Lu Zhang

4

1 reference

11 September 2017

Fei Xue

5

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11 September 2017

Yuanmao Zhu

6

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11 September 2017

Ping Liu

7

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11 September 2017

publication date

16 March 2012

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Molecular Biology Reports

11 September 2017

published in

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11 September 2017

volume

39

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11 September 2017

issue

5

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11 September 2017

page(s)

5867-5873

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https://scigraph.springernature.com/pub.10.1007/s11033-011-1397-7

11 September 2017

exact match

0 references

cites work

Number of people with glaucoma worldwide

1 reference

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The number of people with glaucoma worldwide in 2010 and 2020

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Adult-onset primary open-angle glaucoma caused by mutations in optineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Evaluation of optineurin sequence variations in 1,048 patients with open-angle glaucoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Variants in optineurin gene and their association with tumor necrosis factor-alpha polymorphisms in Japanese patients with glaucoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Molecular genetic analysis of optineurin gene for primary open-angle and normal tension glaucoma in the Japanese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Different optineurin mutation pattern in primary open-angle glaucoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Optineurin in primary open angle glaucoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Defining the pathogenicity of optineurin in juvenile open-angle glaucoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Optineurin increases cell survival and translocates to the nucleus in a Rab8-dependent manner upon an apoptotic stimulus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Transgenic studies on the role of optineurin in the mouse eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Inhibition of metabotropic glutamate receptor signaling by the huntingtin-binding protein optineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Interaction of an adenovirus E3 14.7-kilodalton protein with a novel tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Phorbol esters and cytokines regulate the expression of the NEMO-related protein, a molecule involved in a NF-kappa B-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Current concepts in apoptosis: the physiological suicide program revisited.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Mitochondrial oxidative stress: implications for cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Signal transduction mediated by Bid, a pro-death Bcl-2 family proteins, connects the death receptor and mitochondria apoptosis pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Oxidative stress-induced apoptosis is associated with alterations in mitochondrial caspase activity and Bcl-2-dependent alterations in mitochondrial pH (pHm).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Apoptosis induced by cadmium in human lymphoma U937 cells through Ca2+-calpain and caspase-mitochondria- dependent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Apoptosomes: engines for caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-011-1397-7

Evaluation of Optineurin as a candidate gene in Indian patients with primary open angle glaucoma.

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22422156

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mitochondrial apoptotic pathways.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22422156

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Clinical features and course of patients with glaucoma with the E50K mutation in the optineurin gene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22422156

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S11033-011-1397-7

1 reference

11 September 2017

1 reference