(Q39388182)

11 September 2017

Influence of improved FcRn binding on the subcutaneous bioavailability of monoclonal antibodies in cynomolgus monkeys (English)

1 reference

11 September 2017

1 reference

1 reference

1 reference

Amita Datta-Mannan

1

1 reference

11 September 2017

Derrick R Witcher

series ordinal

2

1 reference

11 September 2017

Jirong Lu

series ordinal

3

1 reference

11 September 2017

Victor J Wroblewski

series ordinal

4

1 reference

11 September 2017

1 March 2012

1 reference

11 September 2017

Monoclonal Antibodies

1 reference

11 September 2017

4

1 reference

11 September 2017

2

1 reference

11 September 2017

267-273

1 reference

Neonatal Fc receptor mediates internalization of Fc in transfected human endothelial cells

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361662

Molecular engineering and design of therapeutic antibodies

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361662

FcRn: the neonatal Fc receptor comes of age.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361662

Elucidation of intracellular recycling pathways leading to exocytosis of the Fc receptor, FcRn, by using multifocal plane microscopy

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361662

Divergent activities of an engineered antibody in murine and human systems have implications for therapeutic antibodies

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361662

Exocytosis of IgG as mediated by the receptor, FcRn: an analysis at the single-molecule level

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361662

Visualizing the site and dynamics of IgG salvage by the MHC class I-related receptor, FcRn.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361662

Increasing the affinity of a human IgG1 for the neonatal Fc receptor: biological consequences.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361662

Increasing the serum persistence of an IgG fragment by random mutagenesis.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361662

Rapid and efficient site-specific mutagenesis without phenotypic selection

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361662

A therapeutic anti-VEGF antibody with increased potency independent of pharmacokinetic half-life

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361662

Monoclonal antibody clearance. Impact of modulating the interaction of IgG with the neonatal Fc receptor

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361662

Engineered human IgG antibodies with longer serum half-lives in primates

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361662

Humanized IgG1 variants with differential binding properties to the neonatal Fc receptor: relationship to pharmacokinetics in mice and primates.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361662

An engineered human IgG1 antibody with longer serum half-life.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361662

Engineering the Fc region of immunoglobulin G to modulate in vivo antibody levels.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361662

Subcutaneous absorption of monoclonal antibodies: role of dose, site of injection, and injection volume on rituximab pharmacokinetics in rats

21 August 2018

1 reference

12 December 2020

Monoclonal antibody pharmacokinetics and pharmacodynamics

1 reference

12 December 2020

Engineering human IgG1 affinity to human neonatal Fc receptor: impact of affinity improvement on pharmacokinetics in primates

1 reference

12 December 2020

Pharmacokinetics of humanized monoclonal anti-tumor necrosis factor-{alpha} antibody and its neonatal Fc receptor variants in mice and cynomolgus monkeys

1 reference

12 December 2020

Identifiers

DOI

10.4161/MABS.4.2.19364

1 reference

11 September 2017

1 reference

11 September 2017

PubMed publication ID

22377715

1 reference