(Q39390866)

English

Treatment with the snail peptide CGX-1007 reduces DNA damage and alters gene expression of c-fos and bcl-2 following focal ischemic brain injury in rats

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Treatment with the snail peptide CGX-1007 reduces DNA damage and alters gene expression of c-fos and bcl-2 following focal ischemic brain injury in rats (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

author name string

A J Williams

1

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

G Ling

2

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

R Berti

3

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

J R Moffett

4

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

C Yao

5

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

X M Lu

6

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

J R Dave

7

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

F C Tortella

8

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

publication date

29 August 2003

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Experimental Brain Research

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

153

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

16-26

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

https://scigraph.springernature.com/pub.10.1007/s00221-003-1566-6

0 references

Expression of c-jun and c-fos in apoptotic cells after DNA damage.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immediate early gene expression in response to cerebral ischemia. Friend or foe?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of inducible transcription factors in apoptotic nerve cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular glutamate during focal cerebral ischaemia in rats: time course and calcium dependency

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear calcium-activated gene expression: possible roles in neuronal plasticity and epileptogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective efficacy and therapeutic window of the high-affinity N-methyl-D-aspartate antagonist conantokin-G: in vitro (primary cerebellar neurons) and in vivo (rat model of transient focal brain ischemia) studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic analogues of conantokin-G: NMDA antagonists acting through a novel polyamine-coupled site.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dextromethorphan protects against cerebral injury following transient, but not permanent, focal ischemia in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction in neuronal death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional changes in c-fos mRNA in rat brain after i.v. or i.c.v. NMDA injections

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of apoptosis by c-Fos protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thermodynamics of binding of calcium, magnesium, and zinc to the N-methyl-D-aspartate receptor ion channel peptidic inhibitors, conantokin-G and conantokin-T.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential pattern of expression of voltage-gated sodium channel genes following ischemic brain injury in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Focal ischemia causes an extensive induction of immediate early genes that are sensitive to MK-801

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteasome inhibitor PS519 reduces infarction and attenuates leukocyte infiltration in a rat model of focal cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Micromolar L-glutamate induces extensive apoptosis in an apoptotic-necrotic continuum of insult-dependent, excitotoxic injury in cultured cortical neurones.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Focal ischemia in rats causes time-dependent expression of c-fos protein immunoreactivity in widespread regions of ipsilateral cortex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conantokin G is an NR2B-selective competitive antagonist of N-methyl-D-aspartate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Occurrence of nonconvulsive seizures, periodic epileptiform discharges, and intermittent rhythmic delta activity in rat focal ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical expression of Bcl-2, Bax and cytochrome c following focal cerebral ischemia and effect of hypothermia in rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia potentiates traumatic brain injury-induced expression of c-fos in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective NR2B NMDA receptor antagonists are protective against staurosporine-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional expression of heat shock protein-70 mRNA and c-fos mRNA following focal ischemia in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in apoptosis-related protein (p53, Bax, Bcl-2 and Fos) expression with DNA fragmentation in the central nervous system in rats after closed head injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective role of c-fos antisense oligonucleotide: in vitro and in vivo studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome c release

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered expression of Bcl-2, Bcl-X, Bax, and c-Fos colocalizes with DNA fragmentation and ischemic cell damage following middle cerebral artery occlusion in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of c-fos, junB, c-jun, and hsp70 mRNA in cortex, thalamus, basal ganglia, and hippocampus following middle cerebral artery occlusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulus-transcription coupling in focal cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of c-fos, heat shock protein 70, neurotrophins, and cyclooxygenase-2 mRNA in response to focal cerebral ischemia/reperfusion in rats and their modification by magnesium sulfate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MK-801 inhibits the induction of immediate early genes in cerebral cortex, thalamus, and hippocampus, but not in substantia nigra following middle cerebral artery occlusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of MK801 binding in adult rat brain sections by conantokin-G and conantokin-T.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EEG spectral analysis of the neuroprotective kappa opioids enadoline and PD117302.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of basic fibroblast growth factor mRNA after transient focal ischemia: comparison with expression of c-fos, c-jun, and hsp 70 mRNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis: overview and signal transduction pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excitotoxins in neuronal apoptosis and necrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CP-101,606, an NR2B subunit selective NMDA receptor antagonist, inhibits NMDA and injury induced c-fos expression and cortical spreading depression in rodents

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrathecal CGX-1007 is neuroprotective in a rat model of focal cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional induction of c-fos mRNA by NMDA: a quantitative in-situ hybridization study

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-dimensional structure of a gamma-carboxyglutamic acid-containing conotoxin, conantokin G, from the marine snail Conus geographus: the metal-free conformer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular Bax translocation after transient cerebral ischemia: implications for a role of the mitochondrial apoptotic signaling pathway in ischemic neuronal death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Continuous c-fos expression precedes programmed cell death in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conformational changes in conantokin-G induced upon binding of calcium and magnesium as revealed by NMR structural analysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative real-time RT-PCR analysis of inflammatory gene expression associated with ischemia-reperfusion brain injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 family gene products in cerebral ischemia and traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/12955387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00221-003-1566-6

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

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