(Q39393508)

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Butyrate activates the monocarboxylate transporter MCT4 expression in breast cancer cells and enhances the antitumor activity of 3-bromopyruvate.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350013%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Butyrate activates the monocarboxylate transporter MCT4 expression in breast cancer cells and enhances the antitumor activity of 3-bromopyruvate (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350013%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

2

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Europe PubMed Central

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23 January 2020

Odília Queirós

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350013%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

João Azevedo-Silva

5

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350013%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Fatima Baltazar

10

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350013%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Margarida Casal

11

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Europe PubMed Central

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23 January 2020

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António Pacheco

3

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23 January 2020

Céline Pinheiro

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350013%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Roxana Moreira

6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350013%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Madalena Pedro

7

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350013%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Young H Ko

8

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350013%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Peter L Pedersen

9

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350013%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

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17 February 2012

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Europe PubMed Central

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23 January 2020

Journal of Bioenergetics and Biomembranes

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350013%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

44

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23 January 2020

1

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23 January 2020

141-153

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22350013%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Regulation of monocarboxylate transporter 1 (MCT1) promoter by butyrate in human intestinal epithelial cells: involvement of NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Intra- and extra-cellular lactate shuttles

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

High aerobic glycolysis of rat hepatoma cells in culture: Role of mitochondrial hexokinase

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Substrate-induced regulation of the human colonic monocarboxylate transporter, MCT1

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

The human colonic monocarboxylate transporter Isoform 1: its potential importance to colonic tissue homeostasis.

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Lactate shuttles at a glance: from physiological paradigms to anti-cancer treatments

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

The H+-linked monocarboxylate transporter (MCT1/SLC16A1): a potential therapeutic target for high-risk neuroblastoma

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Expression of monocarboxylate transporter MCT1 in normal and neoplastic human CNS tissues

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

The SLC16 gene family?from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Mitochondrial and plasma membrane lactate transporter and lactate dehydrogenase isoform expression in breast cancer cell lines.

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Tumor metabolism of lactate: the influence and therapeutic potential for MCT and CD147 regulation

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Glucose catabolism in the rabbit VX2 tumor model for liver cancer: characterization and targeting hexokinase

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP.

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Tumor cell metabolism: cancer's Achilles' heel

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Kinetic analysis of butyrate transport in human colon adenocarcinoma cells reveals two different carrier-mediated mechanisms

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Overview of the proton-coupled MCT (SLC16A) family of transporters: characterization, function and role in the transport of the drug of abuse gamma-hydroxybutyric acid

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Emmprin (basigin/CD147): matrix metalloproteinase modulator and multifunctional cell recognition molecule that plays a critical role in cancer progression

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

The role of mitochondrial hexokinase binding in the abnormal energy metabolism of tumor cell lines

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Warburg, me and Hexokinase 2: Multiple discoveries of key molecular events underlying one of cancers' most common phenotypes, the "Warburg Effect", i.e., elevated glycolysis in the presence of oxygen

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Inhibition of energy-producing pathways of HepG2 cells by 3-bromopyruvate

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Increasing expression of monocarboxylate transporters 1 and 4 along progression to invasive cervical carcinoma.

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Increased expression of monocarboxylate transporters 1, 2, and 4 in colorectal carcinomas.

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Expression of monocarboxylate transporters 1, 2, and 4 in human tumours and their association with CD147 and CD44

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Monocarboxylate transporter 1 is up-regulated in basal-like breast carcinoma.

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

3-Bromopyruvate induces necrotic cell death in sensitive melanoma cell lines

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

High incidence of EMMPRIN expression in human tumors

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Regulation of tumor pH and the role of carbonic anhydrase 9.

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Sulforhodamine B colorimetric assay for cytotoxicity screening.

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

On the Origin of Cancer Cells

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70)

1 reference

https://api.crossref.org/works/10.1007%2FS10863-012-9418-3

21 January 2018

The effects of short-chain fatty acids on human colon cancer cell phenotype are associated with histone hyperacetylation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22350013

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Energy metabolism of tumor cells. Requirement for a form of hexokinase with a propensity for mitochondrial binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/22350013

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of high lactate levels in head and neck tumors with incidence of metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22350013

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The short-chain fatty acid butyrate induces apoptosis in colorectal tumour cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22350013

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The monocarboxylate transporter family--Structure and functional characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/22350013

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microbial degradation products influence colon cancer risk: the butyrate controversy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22350013

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor metabolism: cancer cells give and take lactate

1 reference

https://pubmed.ncbi.nlm.nih.gov/22350013

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effect of tumor cell-derived lactic acid on human T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22350013

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The monocarboxylate transporter family--role and regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22350013

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22350013

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycolytic enzyme inhibitors affect pancreatic cancer survival by modulating its signaling and energetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/22350013

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of high lactate levels in human cervical cancer with incidence of metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22350013

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/22350013

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/22350013

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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