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GSK3 and p53 - is there a link in Alzheimer's disease?
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
2831894
retrieved
11 September 2017
title
GSK3 and p53 - is there a link in Alzheimer's disease?
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2831894
retrieved
11 September 2017
main subject
Alzheimer's disease
0 references
author
Carole J. Proctor
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
2831894
retrieved
11 September 2017
Douglas A Gray
object named as
Douglas A Gray
series ordinal
2
0 references
publication date
26 January 2010
1 reference
stated in
Europe PubMed Central
PMCID
2831894
retrieved
11 September 2017
published in
Molecular Neurodegeneration
1 reference
stated in
Europe PubMed Central
PMCID
2831894
retrieved
11 September 2017
volume
5
1 reference
stated in
Europe PubMed Central
PMCID
2831894
retrieved
11 September 2017
page(s)
7
1 reference
stated in
Europe PubMed Central
PMCID
2831894
retrieved
11 September 2017
exact match
https://scigraph.springernature.com/pub.10.1186/1750-1326-5-7
0 references
cites work
Explaining oscillations and variability in the p53-Mdm2 system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
11 September 2017
Akt and CHIP coregulate tau degradation through coordinated interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
11 September 2017
The GSK3 hypothesis of Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
11 September 2017
Abeta inhibits the proteasome and enhances amyloid and tau accumulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
11 September 2017
An in silico model of the ubiquitin-proteasome system that incorporates normal homeostasis and age-related decline
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
11 September 2017
The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
11 September 2017
The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
11 September 2017
Oscillations and variability in the p53 system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
11 September 2017
BioModels Database: a free, centralized database of curated, published, quantitative kinetic models of biochemical and cellular systems
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
11 September 2017
CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
11 September 2017
Glycogen Synthase Kinase-3β (GSK3β) Binds to and Promotes the Actions of p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
11 September 2017
The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
11 September 2017
Does p53 affect organismal aging?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
11 September 2017
Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
11 September 2017
Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
11 September 2017
Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
11 September 2017
Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
11 September 2017
Regulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegeneration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
11 September 2017
Amyloid deposition as the central event in the aetiology of Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
11 September 2017
Dynamics of the p53-Mdm2 feedback loop in individual cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
14 September 2017
The Wnt pool of glycogen synthase kinase 3beta is critical for trophic-deprivation-induced neuronal death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
14 September 2017
p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
14 September 2017
Presenilin-dependent gamma-secretase-mediated control of p53-associated cell death in Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
14 September 2017
Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
14 September 2017
Tools for the SBML Community.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
21 August 2018
Alzheimer disease and cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
21 August 2018
Intracellular Abeta42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
21 August 2018
Proteolysis of non-phosphorylated and phosphorylated tau by thrombin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
21 August 2018
Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
21 August 2018
Proteasomal degradation of tau protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
21 August 2018
Structural and functional implications of tau hyperphosphorylation: information from phosphorylation-mimicking mutated tau proteins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
21 August 2018
Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831894
retrieved
21 August 2018
Towards an e-biology of ageing: integrating theory and data
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20181016
retrieved
12 December 2020
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Identifiers
DOI
10.1186/1750-1326-5-7
1 reference
stated in
Europe PubMed Central
PMCID
2831894
retrieved
11 September 2017
Dimensions Publication ID
1030084133
0 references
PMCID
2831894
1 reference
stated in
Europe PubMed Central
PMCID
2831894
retrieved
11 September 2017
PubMed ID
20181016
1 reference
stated in
Europe PubMed Central
PMCID
2831894
retrieved
11 September 2017
ResearchGate publication ID
41561318
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