(Q39397461)

11 September 2017

title

Evidence for a relief of repression mechanism for activation of the human telomerase reverse transcriptase promoter (English)

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11 September 2017

Shuwen Wang

1

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11 September 2017

Jiyue Zhu

series ordinal

2

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11 September 2017

language of work or name

English

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publication date

28 February 2003

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Journal of Biological Chemistry

11 September 2017

published in

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11 September 2017

volume

278

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11 September 2017

issue

21

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11 September 2017

page(s)

18842-18850

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The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

11 September 2017

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Telomerase regulation: not just flipping the switch

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Induction of hTERT expression and telomerase activity by estrogens in human ovary epithelium cells

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Telomerase activation by the E6 gene product of human papillomavirus type 16.

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Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation

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Myc activates telomerase

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Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells.

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Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells

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Multiple pathways to cellular senescence: role of telomerase repressors

21 January 2018

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E2F-1 represses transcription of the human telomerase reverse transcriptase gene

21 January 2018

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Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT).

21 January 2018

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In vivo and in vitro analyses of Myc for differential promoter activities of the human telomerase (hTERT) gene in normal and tumor cells.

21 January 2018

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Downstream E-box-mediated regulation of the human telomerase reverse transcriptase (hTERT) gene transcription: evidence for an endogenous mechanism of transcriptional repression

21 January 2018

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Mapping of the gene for the human telomerase reverse transcriptase, hTERT, to chromosome 5p15.33 by fluorescence in situ hybridization

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Molecular basis of artifacts in the detection of telomerase activity and a modified primer for a more robust 'TRAP' assay

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The histone deacetylase inhibitor trichostatin A derepresses the telomerase reverse transcriptase (hTERT) gene in human cells

21 January 2018

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Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells

21 January 2018

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Telomerase activation by histone deacetylase inhibitor in normal cells

21 January 2018

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Micrococcal nuclease digestion of nuclei reveals extended nucleosome ladders having anomalous DNA lengths for chromatin assembled on non-replicating plasmids in transfected cells

21 January 2018

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Histone acetylation and transcriptional regulatory mechanisms

21 January 2018

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21 January 2018

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Implications of mapping the human telomerase gene (hTERT) as the most distal gene on chromosome 5p.

21 January 2018

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Sp1 and chromatin environment are important contributors to the formation of repressive chromatin structures on the transfected human adenine nucleotide translocase-2 promoter

21 January 2018

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SWI/SNF stimulates the formation of disparate activator-nucleosome complexes but is partially redundant with cooperative binding.

21 January 2018

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Structural and functional analyses of DNA bending induced by Sp1 family transcription factors 1 1Edited by T. Richmond

21 January 2018

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Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit

21 January 2018

1 reference

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Evidence for the recessive nature of cellular immortality

21 January 2018

1 reference

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Rearrangements of minisatellites in the human telomerase reverse transcriptase gene are not correlated with its expression in colon carcinomas

21 January 2018

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Nucleosome sliding via TBP DNA binding in vivo

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M209544200

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11 September 2017

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