(Q34535621)

2 August 2017

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title

Regulation of the human telomerase reverse transcriptase gene (English)

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2 August 2017

1

Anne-Lyse Ducrest

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2 August 2017

Henrietta Szutorisz

2

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2 August 2017

Joachim Lingner

series ordinal

3

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2 August 2017

Markus Nabholz

series ordinal

4

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2 August 2017

language of work or name

English

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publication date

1 January 2002

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2 August 2017

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2 August 2017

21

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2 August 2017

541-552

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2 August 2017

4

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205081

2 August 2017

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cites work

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Telomere position effect in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Constitutive telomerase activity in cells with tissue-renewing potential from estrogen-regulated rat tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Extension of life-span by introduction of telomerase into normal human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Mapping of the gene for the human telomerase reverse transcriptase, hTERT, to chromosome 5p15.33 by fluorescence in situ hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Meningiomas, dicentric chromosomes, gliomas, and telomerase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

A new role for hypoxia in tumor progression: induction of fragile site triggering genomic rearrangements and formation of complex DMs and HSRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

E2F-1 represses transcription of the human telomerase reverse transcriptase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Telomerase repressor sequences on chromosome 3 and induction of permanent growth arrest in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Construction and characterization of a highly stable human: rodent monochromosomal hybrid panel for genetic complementation and genome mapping studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Telomere maintenance by recombination in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Identification and characterization of negative regulatory elements of the human telomerase catalytic subunit (hTERT) gene promoter: possible role of MZF-2 in transcriptional repression of hTERT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

E box-dependent activation of telomerase by human papillomavirus type 16 E6 does not require induction of c-myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

The Myc/Max/Mad network and the transcriptional control of cell behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Is telomerase activity in cancer due to selection of stem cells and differentiation arrest?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Telomere dysfunction increases mutation rate and genomic instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Inhibition of telomerase limits the growth of human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Telomeres shorten during ageing of human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

A gene involved in control of human cellular senescence on human chromosome 1q

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

cis-Activation of the human telomerase gene (hTERT) by the hepatitis B virus genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Repression of the telomerase catalytic subunit by a gene on human chromosome 3 that induces cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Telomere shortening is proportional to the size of the G-rich telomeric 3'-overhang.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Specific association of human telomerase activity with immortal cells and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus transactivates the telomerase reverse transcriptase promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Construction of mouse A9 clones containing a single human chromosome tagged with neomycin-resistance gene via microcell fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Expression of TERT in early premalignant lesions and a subset of cells in normal tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Mouse A9 cells containing single human chromosomes for analysis of genomic imprinting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Essential role of mouse telomerase in highly proliferative organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

High-resolution chromosome 3p allelotyping of breast carcinomas and precursor lesions demonstrates frequent loss of heterozygosity and a discontinuous pattern of allele loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Induction of hTERT expression and telomerase activity by estrogens in human ovary epithelium cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Absence of cancer-associated changes in human fibroblasts immortalized with telomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Introduction of chromosome 7 suppresses telomerase with shortening of telomeres in a human mesothelial cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Telomerase catalytic subunit homologs from fission yeast and human

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Isolation of monochromosomal hybrids following fusion of human diploid fibroblast-derived microcells with mouse A9 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Functional evidence for a telomerase repressor gene on human chromosome 10p15.1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Mysterious liaisons: the relationship between c-Myc and the cell cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

In vivo and in vitro analyses of Myc for differential promoter activities of the human telomerase (hTERT) gene in normal and tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Identification of Mad as a repressor of the human telomerase (hTERT) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Telomerase activation by human papillomavirus type 16 E6 protein: induction of human telomerase reverse transcriptase expression through Myc and GC-rich Sp1 binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Restoration of the cellular senescence program and repression of telomerase by human chromosome 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Multiple pathways to cellular senescence: role of telomerase repressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Radiation-induced chromatid breaks and deficient DNA repair in cancer predisposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Retinoids down-regulate telomerase and telomere length in a pathway distinct from leukemia cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

A telomere-independent senescence mechanism is the sole barrier to Syrian hamster cell immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

21 January 2018

Aneuploidy and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

The reactivation of telomerase activity in cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Telomerase suppression by chromosome 6 in a human papillomavirus type 16-immortalized keratinocyte cell line and in a cervical cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Telomerase activation by histone deacetylase inhibitor in normal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Telomerase-independent senescence of human immortal cells induced by microcell-mediated chromosome transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Evidence for a putative telomerase repressor gene in the 3p14.2-p21.1 region

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

TRF2 Protects Human Telomeres from End-to-End Fusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Characterization of terminal deletions at 7q32 and 22q13.3 healed by De novo telomere addition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Transcriptional activation of the telomerase hTERT gene by human papillomavirus type 16 E6 oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

21 January 2018

Myc activates telomerase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Genomic organization and promoter characterization of the gene encoding the human telomerase reverse transcriptase (hTERT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Direct activation of TERT transcription by c-MYC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Expression of telomerase genes correlates with telomerase activity in human colorectal carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Human endothelial cell life extension by telomerase expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

Telomere elongation in immortal human cells without detectable telomerase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

7 January 2021

Chromosome healing by addition of telomeric repeats in wheat occurs during the first mitotic divisions of the sporophyte and is a gradual process

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

7 January 2021

Induction of telomerase activity by in vivo X-irradiation of mouse splenocytes and its possible role in chromosome healing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

7 January 2021

Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

7 January 2021

Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

7 January 2021

Is estradiol a genotoxic mutagenic carcinogen?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

7 January 2021

Cutting edge: telomerase activation in human T lymphocytes does not require increase in telomerase reverse transcriptase (hTERT) protein but is associated with hTERT phosphorylation and nuclear translocation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

7 January 2021

The Wilms' tumor 1 tumor suppressor gene represses transcription of the human telomerase reverse transcriptase gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

7 January 2021

Proliferation-associated regulation of telomerase activity in human endometrium and its potential implication in early cancer diagnosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

7 January 2021

Rearrangements of minisatellites in the human telomerase reverse transcriptase gene are not correlated with its expression in colon carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

7 January 2021

Tissue-specific alternate splicing of human telomerase reverse transcriptase (hTERT) influences telomere lengths during human development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

7 January 2021

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

7 January 2021

Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205081

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205081

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Dimensions Publication ID

2 August 2017

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1 reference