(Q39400633)

English

Expression of IL-15 in NK cells results in rapid enrichment and selective cytotoxicity of gene-modified effectors that carry a tumor-specific antigen receptor

scientific article published on 5 February 2012

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scholarly article

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Europe PubMed Central

PubMed publication ID

11 September 2017

Expression of IL-15 in NK cells results in rapid enrichment and selective cytotoxicity of gene-modified effectors that carry a tumor-specific antigen receptor (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

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author name string

Christiane Sahm

1

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Kurt Schönfeld

2

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Winfried S Wels

3

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

publication date

5 February 2012

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Europe PubMed Central

PubMed publication ID

11 September 2017

Cancer Immunology, Immunotherapy

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Europe PubMed Central

PubMed publication ID

11 September 2017

61

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Europe PubMed Central

PubMed publication ID

11 September 2017

9

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Europe PubMed Central

PubMed publication ID

11 September 2017

1451-1461

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

https://scigraph.springernature.com/pub.10.1007/s00262-012-1212-x

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Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity

1 reference

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Chimeric antigen receptors for the retargeting of cytotoxic effector cells

1 reference

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21 January 2018

Costimulation tunes tumor-specific activation of redirected T cells in adoptive immunotherapy

1 reference

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Ex vivo gene transfer for improved adoptive immunotherapy of cancer

1 reference

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Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia

1 reference

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Recombinant immunotoxins and retargeted killer cells: employing engineered antibody fragments for tumor-specific targeting of cytotoxic effectors.

1 reference

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21 January 2018

Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells

1 reference

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21 January 2018

Up on the tightrope: natural killer cell activation and inhibition

1 reference

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21 January 2018

Natural killer cell-based immunotherapeutic strategies

1 reference

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21 January 2018

Cellular Immunotherapy of Malignancies Using the Clonal Natural Killer Cell Line NK-92

1 reference

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21 January 2018

Infusion of the allogeneic cell line NK-92 in patients with advanced renal cell cancer or melanoma: a phase I trial

1 reference

https://api.crossref.org/works/10.1007%2FS00262-012-1212-X

21 January 2018

Expression of a CD20-specific chimeric antigen receptor enhances cytotoxic activity of NK cells and overcomes NK-resistance of lymphoma and leukemia cells

1 reference

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21 January 2018

NK cells engineered to express a GD2 -specific antigen receptor display built-in ADCC-like activity against tumour cells of neuroectodermal origin.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-012-1212-X

21 January 2018

Factors regulating the cytotoxic activity of the human natural killer cell line, NK-92.

1 reference

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21 January 2018

Functions of γC cytokines in immune homeostasis: current and potential clinical applications

1 reference

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21 January 2018

Growth and apoptosis of human natural killer cell neoplasms: role of interleukin-2/15 signaling

1 reference

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21 January 2018

Interleukin-2, interleukin-15, and their roles in human natural killer cells

1 reference

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21 January 2018

High-level transduction and gene expression in hematopoietic repopulating cells using a human immunodeficiency [correction of imunodeficiency] virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoter

1 reference

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Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

1 reference

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21 January 2018

Trans-presentation: a novel mechanism regulating IL-15 delivery and responses

1 reference

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21 January 2018

Transfection with mRNA for CD19 specific chimeric antigen receptor restores NK cell mediated killing of CLL cells

1 reference

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21 January 2018

Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety

1 reference

https://api.crossref.org/works/10.1007%2FS00262-012-1212-X

21 January 2018

IL-12 release by engineered T cells expressing chimeric antigen receptors can effectively Muster an antigen-independent macrophage response on tumor cells that have shut down tumor antigen expression

1 reference

https://api.crossref.org/works/10.1007%2FS00262-012-1212-X

21 January 2018

Functional characterization of interleukin-15 gene transduction into the human natural killer cell line NKL.

1 reference

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21 January 2018

Secretion and biological activity of short signal peptide IL-15 is chaperoned by IL-15 receptor alpha in vivo

1 reference

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21 January 2018

Mechanism of autocrine stimulation in hematopoietic cells producing interleukin-3 after retrovirus-mediated gene transfer

1 reference

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21 January 2018

Targeting IL-2 to the endoplasmic reticulum confines autocrine growth stimulation to NK-92 cells.

1 reference

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21 January 2018

The emerging role of EpCAM in cancer and stem cell signaling

1 reference

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21 January 2018

EpCAM in carcinogenesis: the good, the bad or the ugly

1 reference

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21 January 2018

Immunotherapy of malignant melanoma in a SCID mouse model using the highly cytotoxic natural killer cell line NK-92.

1 reference

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21 January 2018

Identifiers

10.1007/S00262-012-1212-X

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

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