(Q39402103)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22302684%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Increased radioresistance via G12S K-Ras by compensatory upregulation of MAPK and PI3K pathways in epithelial cancer (English)

1 reference

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22 January 2020

4

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22 January 2020

author name string

Annette Affolter

1

1 reference

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22 January 2020

Martynas Drigotas

2

1 reference

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22 January 2020

Kai Fruth

3

1 reference

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22 January 2020

Christoph Brochhausen

5

1 reference

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22 January 2020

Wolf J Mann

6

1 reference

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22 January 2020

Jürgen Brieger

7

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22 January 2020

publication date

2 February 2012

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22 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22302684%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

35

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22 January 2020

issue

2

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22 January 2020

page(s)

220-228

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22302684%20AND%20SRC:MED&resulttype=core&format=json

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

22 January 2020

cites work

1 reference

Oncogenic H-Ras up-regulates expression of Ku80 to protect cells from gamma-ray irradiation in NIH3T3 cells

21 January 2018

1 reference

Molecular targets for altering radiosensitivity: lessons from Ras as a pre-clinical and clinical model

21 January 2018

1 reference

Roles of the PI-3K and MEK pathways in Ras-mediated chemoresistance in breast cancer cells.

21 January 2018

1 reference

The ras oncogenes increase the intrinsic resistance of NIH 3T3 cells to ionizing radiation

21 January 2018

1 reference

KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer.

21 January 2018

1 reference

Increased radioresistance of EJras-transformed human osteosarcoma cells and its modulation by lovastatin, an inhibitor of p21ras isoprenylation

21 January 2018

1 reference

Activation of mitogen-activated protein kinase extracellular signal-related kinase in head and neck squamous cell carcinomas after irradiation as part of a rescue mechanism.

21 January 2018

1 reference

Ionizing radiation-induced mitogen-activated protein (MAP) kinase activation in DU145 prostate carcinoma cells: MAP kinase inhibition enhances radiation-induced cell killing and G2/M-phase arrest

21 January 2018

1 reference

Effect of antisense c-raf-1 on tumorigenicity and radiation sensitivity of a human squamous carcinoma.

21 January 2018

1 reference

Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit

21 January 2018

1 reference

Akt1 suppresses radiation-induced germ cell apoptosis in vivo.

21 January 2018

1 reference

Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair.

21 January 2018

1 reference

Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition

21 January 2018

1 reference

Molecular biologic characteristics of seven new cell lines of squamous cell carcinomas of the head and neck and comparison to fresh tumor tissue

21 January 2018

1 reference

Molecular mechanisms of radiation-induced accelerated repopulation

21 January 2018

1 reference

Stress and radiation-induced activation of multiple intracellular signaling pathways

21 January 2018

1 reference

Differential activation of the phosphatidylinositol 3'-kinase/Akt survival pathway by ionizing radiation in tumor and primary endothelial cells

21 January 2018

1 reference

Ionizing radiation activates Erb-B receptor dependent Akt and p70 S6 kinase signaling in carcinoma cells

21 January 2018

1 reference

The PI3K-PDK1 connection: more than just a road to PKB

21 January 2018

1 reference

Akt is a direct target of the phosphatidylinositol 3-kinase. Activation by growth factors, v-src and v-Ha-ras, in Sf9 and mammalian cells

21 January 2018

1 reference

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

21 January 2018

1 reference

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

1 reference

Molecular strategies targeting the host component of cancer to enhance tumor response to radiation therapy

21 January 2018

1 reference

Phosphoinositide 3-kinase inhibition in cancer treatment

21 January 2018

1 reference

Molecular alterations associated with improved survival in pancreatic cancer patients treated with radiation or chemotherapy

21 January 2018

1 reference

7 January 2021

Radioresistance induced by oncogenic transformation

1 reference

7 January 2021

A direct interaction between oncogenic Ha-Ras and phosphatidylinositol 3-kinase is not required for Ha-Ras-dependent transformation of epithelial cells

1 reference

7 January 2021

Selective inhibition of Ras, phosphoinositide 3 kinase, and Akt isoforms increases the radiosensitivity of human carcinoma cell lines

1 reference

7 January 2021

The role of the H-ras oncogene in radiation resistance and metastasis

1 reference

7 January 2021

Identifiers

DOI

10.1002/HED.22954

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22302684%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference