(Q37331610)

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Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition

scientific article published on January 2009

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Europe PubMed Central

PMC publication ID

19 August 2017

Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition (English)

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Europe PubMed Central

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19 August 2017

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Zachary A Knight

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Zachary Knight

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Sanchita Bhattacharyaa

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Sanchita Bhattacharya

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19 August 2017

Gordon B. Mills

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Gordon B Mills

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19 August 2017

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Joe W Gray

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19 August 2017

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Laura M Heiser

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19 August 2017

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Mina J Bissell

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19 August 2017

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Paul T Spellman

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19 August 2017

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Olga K Mirzoeva

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19 August 2017

Debopriya Das

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19 August 2017

Doris Siwak

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19 August 2017

Rina Gendelman

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19 August 2017

Nora Bayani

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19 August 2017

Nicholas J Wang

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19 August 2017

Richard M Neve

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19 August 2017

Yinghui Guan

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19 August 2017

Zhi Hu

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19 August 2017

Heidi S Feiler

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19 August 2017

Philippe Gascard

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19 August 2017

Kevan M Shokat

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19 August 2017

Andrew J Wyrobek

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19 August 2017

Frank McCormick

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19 August 2017

Wen-Lin Kuo

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W Michael Korn

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19 August 2017

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publication date

1 January 2009

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19 August 2017

Cancer Research

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19 August 2017

69

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19 August 2017

2

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19 August 2017

565-572

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19 August 2017

Individualized molecular medicine: linking functional proteomics to select therapeutics targeting the PI3K pathway for specific patients

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1 reference

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EGFR associated expression profiles vary with breast tumor subtype

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High-throughput protein expression analysis using tissue microarray technology of a large well-characterised series identifies biologically distinct classes of breast cancer confirming recent cDNA expression analyses

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PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma

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Use of reverse phase protein microarrays and reference standard development for molecular network analysis of metastatic ovarian carcinoma.

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Multicenter phase II study of the oral MEK inhibitor, CI-1040, in patients with advanced non-small-cell lung, breast, colon, and pancreatic cancer

1 reference

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High frequency of mutations of the PIK3CA gene in human cancers

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Proteomic profiling of the NCI-60 cancer cell lines using new high-density reverse-phase lysate microarrays

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Statistical significance for genomewide studies

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Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

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Molecular portraits of human breast tumours

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Eukaryotic Translation Initiation Factor 4E Regulates Expression of Cyclin D1 at Transcriptional and Post-transcriptional Levels

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ERK negatively regulates the epidermal growth factor-mediated interaction of Gab1 and the phosphatidylinositol 3-kinase

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1 reference

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12 December 2020

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10.1158/0008-5472.CAN-08-3389

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Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

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Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

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Europe PubMed Central

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19 August 2017

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