(Q39411267)

English

Membrane-tethered MUC1 mucin is phosphorylated by epidermal growth factor receptor in airway epithelial cells and associates with TLR5 to inhibit recruitment of MyD88.

scientific article published on 16 January 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

Membrane-tethered MUC1 mucin is phosphorylated by epidermal growth factor receptor in airway epithelial cells and associates with TLR5 to inhibit recruitment of MyD88. (English)

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

toll-like receptor

0 references

phosphorylation

0 references

author name string

Kosuke Kato

1

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

Erik P Lillehoj

2

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

Yong Sung Park

3

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

Tsuyoshi Umehara

4

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

Nicholas E Hoffman

5

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

Muniswamy Madesh

6

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

K Chul Kim

7

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

language of work or name

0 references

publication date

16 January 2012

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

Journal of Immunology

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

188

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

4

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

2014-2022

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

Antiinflammatory role of MUC1 mucin during infection with nontypeable Haemophilus influenzae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

Toll-like receptors and their crosstalk with other innate receptors in infection and immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

Muc1 cell surface mucin attenuates epithelial inflammation in response to a common mucosal pathogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

MUC1 expression by human airway epithelial cells mediates Pseudomonas aeruginosa adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

Bovine Muc1 inhibits binding of enteric bacteria to Caco-2 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

Mucins in cancer: function, prognosis and therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

MUC1 limits Helicobacter pylori infection both by steric hindrance and by acting as a releasable decoy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

Bovine Muc1 is a highly polymorphic gene encoding an extensively glycosylated mucin that binds bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

MUC1-C oncoprotein functions as a direct activator of the nuclear factor-kappaB p65 transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

Mucins in the mucosal barrier to infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

Epidermal growth factor receptor-mediated innate immune responses and their roles in airway diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

MUC1 mucin: a peacemaker in the lung

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

Fusions of dendritic cells with breast carcinoma stimulate the expansion of regulatory T cells while concomitant exposure to IL-12, CpG oligodeoxynucleotides, and anti-CD3/CD28 promotes the expansion of activated tumor reactive cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

MUC1 oncoprotein activates the IkappaB kinase beta complex and constitutive NF-kappaB signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

Structure and function of the cell surface (tethered) mucins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

MUC1 cell surface mucin is a critical element of the mucosal barrier to infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

Human airway epithelial cells sense Pseudomonas aeruginosa infection via recognition of flagellin by Toll-like receptor 5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

Ubiquitin signalling in the NF-kappaB pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

Cigarette smoke induces MUC5AC mucin overproduction via tumor necrosis factor-alpha-converting enzyme in human airway epithelial (NCI-H292) cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

Tumor necrosis factor alpha-converting enzyme mediates MUC5AC mucin expression in cultured human airway epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

MUC1, the renaissance molecule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-catenin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

Structural basis for signal transduction by the Toll/interleukin-1 receptor domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

Cloning and sequencing of a human pancreatic tumor mucin cDNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

11 September 2017

Pseudomonas aeruginosa induces vascular endothelial growth factor synthesis in airway epithelium in vitro and in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

14 September 2017

Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

14 September 2017

MUC1 mucin is a negative regulator of toll-like receptor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

14 September 2017

Phosphoinositide 3-kinase is activated by MUC1 but not responsible for MUC1-induced suppression of Toll-like receptor 5 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

14 September 2017

TNF-alpha induces MUC1 gene transcription in lung epithelial cells: its signaling pathway and biological implication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

14 September 2017

TLR5-mediated phosphoinositide 3-kinase activation negatively regulates flagellin-induced proinflammatory gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

14 September 2017

Neutrophil elastase induces IL-8 gene transcription and protein release through p38/NF-{kappa}B activation via EGFR transactivation in a lung epithelial cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

14 September 2017

MUC1 tyrosine phosphorylation activates the extracellular signal-regulated kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

14 September 2017

Identification of four sites of stimulated tyrosine phosphorylation in the MUC1 cytoplasmic tail

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

14 September 2017

Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

25 September 2017

Cigarette smoke induces epidermal growth factor receptor-dependent redistribution of apical MUC1 and junctional beta-catenin in polarized human airway epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

15 June 2018

Tyrosine phosphorylation of the MUC1 breast cancer membrane proteins. Cytokine receptor-like molecules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

15 June 2018

TNF-α is a key regulator of MUC1, an anti-inflammatory molecule, during airway Pseudomonas aeruginosa infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

21 August 2018

Neutrophil elastase stimulates MUC1 gene expression through increased Sp1 binding to the MUC1 promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

21 August 2018

Nuclear association of the cytoplasmic tail of MUC1 and beta-catenin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

21 August 2018

Delayed mammary tumor progression in Muc-1 null mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310431

21 August 2018

Construction and characterization of a chimeric receptor containing the cytoplasmic domain of MUC1 mucin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22250084

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muc1 mucins on the cell surface are adhesion sites for Pseudomonas aeruginosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/22250084

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of Pseudomonas aeruginosa flagellin as an adhesin for Muc1 mucin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22250084

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An essential role for ectodomain shedding in mammalian development

1 reference

https://pubmed.ncbi.nlm.nih.gov/22250084

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: enhanced pulmonary clearance of Pseudomonas aeruginosa by Muc1 knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22250084

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.1102405

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 September 2017

ResearchGate publication ID

0 references

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