(Q39412077)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18420405%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18420405%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18420405%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

7

James H McKerrow

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18420405%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

2

Anang Shelat

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18420405%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

5

Michele Connelly

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18420405%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

6

Fangyi Zhu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18420405%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

4

Conor R Caffrey

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18420405%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1

Jeremy P Mallari

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18420405%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

3

Aaron Kosinski

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18420405%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

language of work or name

English

0 references

publication date

8 April 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18420405%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

number of pages

3

1 reference

Bioorganic & Medicinal Chemistry Letters

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18420405%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18420405%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18420405%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

page(s)

2883-2885

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18420405%20AND%20SRC:MED&resulttype=core&format=json

Blood-brain barrier traversal by African trypanosomes requires calcium signaling induced by parasite cysteine protease

5 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435229

A cathepsin B-like protease is required for host protein degradation in Trypanosoma brucei

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435229

Synthesis and structure-activity relationships of parasiticidal thiosemicarbazone cysteine protease inhibitors against Plasmodium falciparum, Trypanosoma brucei, and Trypanosoma cruzi

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435229

Active site mapping, biochemical properties and subcellular localization of rhodesain, the major cysteine protease of Trypanosoma brucei rhodesiense

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435229

The phenomenon of treatment failures in Human African Trypanosomiasis

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435229

Risk factors for treatment failure after melarsoprol for Trypanosoma brucei gambiense trypanosomiasis in Uganda

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435229

Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435229

Trypanosoma brucei: killing of bloodstream forms in vitro and in vivo by the cysteine proteinase inhibitor Z-phe-ala-CHN2.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435229

2-Acetylpyridine thiosemicarbazones. 1. A new class of potential antimalarial agents

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435229

Lysis of trypanosomes by peptidyl fluoromethyl ketones

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435229

Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435229

Synthesis and structure-activity relationship study of potent trypanocidal thio semicarbazone inhibitors of the trypanosomal cysteine protease cruzain

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435229

Cysteine proteinase inhibitors kill cultured bloodstream forms of Trypanosoma brucei brucei

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2435229

2-Acetylpyridine thiosemicarbazones. 6.2-Acetylpyridine and 2-butyrylpyridine thiosemicarbazones as antileukemic agents

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18420405

12 December 2020

inferred from PubMed ID database lookup

2-acetylpyridine thiosemicarbazones. 13. Derivatives with antifilarial activity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18420405

12 December 2020

inferred from PubMed ID database lookup

Studies of the antineoplastic activity and metabolism of -(N)-heterocyclic carboxaldehyde thiosemicarbazones in dogs and mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18420405

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.BMCL.2008.03.083

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18420405%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18420405%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference