(Q39418496)

11 September 2017

title

Tolfenamic acid inhibits neuroblastoma cell proliferation and induces apoptosis: a novel therapeutic agent for neuroblastoma (English)

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11 September 2017

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ChEBI release 2020-05-28

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Don Eslin

1

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11 September 2017

Umesh T Sankpal

2

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11 September 2017

Chris Lee

3

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11 September 2017

Robert M Sutphin

4

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11 September 2017

Pius Maliakal

5

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Erika Currier

6

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11 September 2017

Giselle Sholler

7

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Moeez Khan

8

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11 September 2017

Riyaz Basha

9

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11 September 2017

publication date

28 December 2011

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11 September 2017

published in

Molecular Carcinogenesis

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11 September 2017

volume

52

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11 September 2017

issue

5

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11 September 2017

page(s)

377-386

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Neuroblastoma - developmental and molecular biology meet therapy design.

11 September 2017

cites work

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Neuroblastoma: biology and molecular and chromosomal pathology

21 January 2018

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Resveratrol inhibits tumor growth of human neuroblastoma and mediates apoptosis by directly targeting mitochondria

21 January 2018

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Sodium ascorbate induces apoptosis in neuroblastoma cell lines by interfering with iron uptake

21 January 2018

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Tolfenamic acid and pancreatic cancer growth, angiogenesis, and Sp protein degradation

21 January 2018

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Therapeutic applications of NSAIDS in cancer: special emphasis on tolfenamic acid

21 January 2018

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Transcription factor Sp1 functions as an anchor protein in gene transcription of human 12(S)-lipoxygenase

21 January 2018

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Tolfenamic acid inhibits ovarian cancer cell growth and decreases the expression of c-Met and survivin through suppressing specificity protein transcription factors.

21 January 2018

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Tolfenamic acid enhances pancreatic cancer cell and tumor response to radiation therapy by inhibiting survivin protein expression

21 January 2018

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Association between high levels of expression of the TRK gene and favorable outcome in human neuroblastoma

21 January 2018

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The MYCN enigma: significance of MYCN expression in neuroblastoma

21 January 2018

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Multiple roles of COX-2 in tumor angiogenesis: a target for antiangiogenic therapy

21 January 2018

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Inhibition of angiogenesis by NSAIDs: molecular mechanisms and clinical implications

21 January 2018

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Tolfenamic acid decreases c-Met expression through Sp proteins degradation and inhibits lung cancer cells growth and tumor formation in orthotopic mice

21 January 2018

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Association between expression of transcription factor Sp1 and increased vascular endothelial growth factor expression, advanced stage, and poor survival in patients with resected gastric cancer

21 January 2018

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Tolfenamic acid interrupts the de novo synthesis of the β-amyloid precursor protein and lowers amyloid beta via a transcriptional pathway.

21 January 2018

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The ability of tolfenamic acid to penetrate the brain: a model for testing the brain disposition of candidate Alzheimer's drugs using multiple platforms.

21 January 2018

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IAP family proteins--suppressors of apoptosis

21 January 2018

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Survivin: key regulator of mitosis and apoptosis and novel target for cancer therapeutics

21 January 2018

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The case for survivin as a regulator of microtubule dynamics and cell-death decisions

21 January 2018

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Repression of BIRC5/survivin by FOXO3/FKHRL1 sensitizes human neuroblastoma cells to DNA damage-induced apoptosis

21 January 2018

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Sp1 upregulates survivin expression in adenocarcinoma of lung cell line A549.

21 January 2018

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Functional significance of a putative sp1 transcription factor binding site in the survivin gene promoter

21 January 2018

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Sp1 and Sp3 regulate basal transcription of the survivin gene

21 January 2018

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Curcumin inhibits NFkappaB mediated radioprotection and modulate apoptosis related genes in human neuroblastoma cells

21 January 2018

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Nifurtimox induces apoptosis of neuroblastoma cells in vitro and in vivo

21 January 2018

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Neuroblastoma: a clinical challenge and biologic puzzle

21 January 2018

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Tolfenamic acid inhibits esophageal cancer through repression of specificity proteins and c-Met.

21 January 2018

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Targeting survivin in cancer therapy: fulfilled promises and open questions

21 January 2018

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The expression of antiapoptotic protein survivin is transcriptionally upregulated by DEC1 primarily through multiple sp1 binding sites in the proximal promoter

21 January 2018

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Downregulation of Bim by brain-derived neurotrophic factor activation of TrkB protects neuroblastoma cells from paclitaxel but not etoposide or cisplatin-induced cell death

21 January 2018

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Survivin inhibition induces human neural tumor cell death through caspase-independent and -dependent pathways

21 January 2018

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Targeting the cell division cycle in cancer: CDK and cell cycle checkpoint kinase inhibitors

21 January 2018

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A recombinant adenovirus expressing p27Kip1 induces cell cycle arrest and loss of cyclin-Cdk activity in human breast cancer cells

21 January 2018

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Piceatannol, a natural stilbene from grapes, induces G1 cell cycle arrest in androgen-insensitive DU145 human prostate cancer cells via the inhibition of CDK activity

21 January 2018

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Cyclins, cyclin-dependent kinases and cdk inhibitors: implications in cell cycle control and cancer

21 January 2018

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Rb inactivation in cell cycle and cancer: the puzzle of highly regulated activating phosphorylation of CDK4 versus constitutively active CDK-activating kinase.

21 January 2018

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Gastrointestinal tolerance studies on tolfenamic acid in humans and animals

21 January 2018

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Recent advances in neuroblastoma

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/MC.21866

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11 September 2017

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