(Q39423631)

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A novel conditionally replicating adenoviral vector with dual expression of IL-24 and arresten inserted in E1 and the region between E4 and fiber for improved melanoma therapy.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22193628%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

A novel conditionally replicating adenoviral vector with dual expression of IL-24 and arresten inserted in E1 and the region between E4 and fiber for improved melanoma therapy (English)

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Europe PubMed Central

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19 January 2020

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19 January 2020

author name string

L Chai

1

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19 January 2020

S Liu

2

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19 January 2020

D Wang

4

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19 January 2020

X Li

5

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19 January 2020

X Zheng

6

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19 January 2020

H Xia

7

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19 January 2020

publication date

23 December 2011

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19 January 2020

Cancer Gene Therapy

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19 January 2020

19

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19 January 2020

4

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19 January 2020

247-254

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19 January 2020

https://scigraph.springernature.com/pub.10.1038/cgt.2011.84

0 references

A probasin promoter, conditionally replicating adenovirus that expresses the sodium iodide symporter (NIS) for radiovirotherapy of prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

Treatment of pancreatic cancer with an oncolytic adenovirus expressing interleukin-12 in Syrian hamsters.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

Armed replicating adenoviruses for cancer virotherapy

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

Oncolytic Viruses for Cancer Therapy: Overcoming the Obstacles

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

The E3-11.6-kDa adenovirus death protein (ADP) is required for efficient cell death: characterization of cells infected with adp mutants

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

Overexpression of adenovirus E3-11.6K protein induces cell killing by both caspase-dependent and caspase-independent mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

E3 gene manipulations affect oncolytic adenovirus activity in immunocompetent tumor models

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

Deletion of the E3-6.7K/gp19K region reduces the persistence of wild-type adenovirus in a permissive tumor model in Syrian hamsters

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

Interleukin-10 and related cytokines and receptors

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

Dual cancer-specific targeting strategy cures primary and distant breast carcinomas in nude mice

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

N-glycosylation of MDA-7/IL-24 is dispensable for tumor cell-specific apoptosis and "bystander" antitumor activity

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24): novel gene therapeutic for metastatic melanoma

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

MDA-7/IL-24 as a cancer therapeutic: from bench to bedside

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

An armed oncolytic adenovirus system, ZD55-gene, demonstrating potent antitumoral efficacy

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

Suppression of tumor growth by oncolytic adenovirus-mediated delivery of an antiangiogenic gene, soluble Flt-1.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

The antitumor activity of TRAIL and IL-24 with replicating oncolytic adenovirus in colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

A simple method for the rapid generation of recombinant adenovirus vectors

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

Genetically modified adenoviral vector with the protein transduction domain of Tat improves gene transfer to CAR-deficient cells

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

Intratumoral coinjection of adenoviral vectors expressing IL-2 and IL-12 results in enhanced frequency of regression of injected and untreated distal tumors

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

Combined TRAIL and Bax gene therapy prolonged survival in mice with ovarian cancer xenograft

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

Inhibition of Src kinase activity by Ad-mda7 suppresses vascular endothelial growth factor expression in prostate carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

Characterization of the anti-angiogenic properties of arresten, an alpha1beta1 integrin-dependent collagen-derived tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

Human alpha1 type IV collagen NC1 domain exhibits distinct antiangiogenic activity mediated by alpha1beta1 integrin

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

21 January 2018

Overexpression of the ADP (E3-11.6K) protein increases cell lysis and spread of adenovirus

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

7 January 2021

based on heuristic

inferred from DOI database lookup

Historical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical and local biological effects of an intratumoral injection of mda-7 (IL24; INGN 241) in patients with advanced carcinoma: a phase I study

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.84

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/CGT.2011.84

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22193628%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22193628%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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