(Q39425423)

11 September 2017

title

Localization of mature neprilysin in lipid rafts (English)

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Membrane metalloendopeptidase

11 September 2017

main subject

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GOA release 2020-03-11

cardiolipin binding

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GOA release 2020-03-11

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Kimihiko Sato

1

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11 September 2017

Chiaki Tanabe

2

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11 September 2017

Yoji Yonemura

3

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11 September 2017

Haruhiko Watahiki

4

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11 September 2017

Yimeng Zhao

5

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11 September 2017

Sosuke Yagishita

6

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11 September 2017

Maiko Ebina

7

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11 September 2017

Satoshi Suo

8

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11 September 2017

Eugene Futai

9

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11 September 2017

Masayuki Murata

10

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11 September 2017

Shoichi Ishiura

11

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11 September 2017

publication date

20 December 2011

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Journal of Neuroscience Research

11 September 2017

published in

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11 September 2017

volume

90

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11 September 2017

issue

4

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11 September 2017

page(s)

870-877

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Review on the APP/PS1KI mouse model: intraneuronal Abeta accumulation triggers axonopathy, neuron loss and working memory impairment

11 September 2017

cites work

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Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice

21 January 2018

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Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein

21 January 2018

1 reference

Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology

21 January 2018

1 reference

Effects of neprilysin chimeric proteins targeted to subcellular compartments on amyloid beta peptide clearance in primary neurons

21 January 2018

1 reference

Alzheimer's disease: the amyloid cascade hypothesis

21 January 2018

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Age-dependent decline of neprilysin in Alzheimer's disease and normal brain: inverse correlation with A beta levels.

21 January 2018

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Mutagenesis of Glu403 to Cys in rabbit neutral endopeptidase-24.11 (neprilysin) creates a disulphide-linked homodimer: analogy with endothelin-converting enzyme

21 January 2018

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Metabolic regulation of brain Abeta by neprilysin.

21 January 2018

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Region-specific reduction of A beta-degrading endopeptidase, neprilysin, in mouse hippocampus upon aging

21 January 2018

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Presynaptic localization of neprilysin contributes to efficient clearance of amyloid-beta peptide in mouse brain.

21 January 2018

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Interactions of amyloid beta-protein with various gangliosides in raft-like membranes: importance of GM1 ganglioside-bound form as an endogenous seed for Alzheimer amyloid

21 January 2018

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Human neprilysin is capable of degrading amyloid beta peptide not only in the monomeric form but also the pathological oligomeric form

21 January 2018

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Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease.

21 January 2018

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Proteins of the kidney microvillar membrane. Reconstitution of endopeptidase in liposomes shows that it is a short-stalked protein

21 January 2018

1 reference

The role of apolipoprotein E in Alzheimer's disease

21 January 2018

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Intracellular Abeta and cognitive deficits precede beta-amyloid deposition in transgenic arcAbeta mice

21 January 2018

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Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10.

21 January 2018

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Role of glycosylation in transport and enzymic activity of neutral endopeptidase-24.11.

21 January 2018

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Lipid rafts: heterogeneity on the high seas

21 January 2018

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Rafts defined: a report on the Keystone Symposium on Lipid Rafts and Cell Function.

21 January 2018

1 reference

Asymmetric localization of flotillins/reggies in preassembled platforms confers inherent polarity to hematopoietic cells

21 January 2018

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Caveolae/lipid rafts in fibroblast-like synoviocytes: ectopeptidase-rich membrane microdomains

21 January 2018

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Alzheimer's disease is a synaptic failure

21 January 2018

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Brain-derived neurotrophic factor regulates cholesterol metabolism for synapse development

21 January 2018

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Depletion of cellular cholesterol and lipid rafts increases shedding of CD30.

21 January 2018

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Gamma-secretase activity is present in rafts but is not cholesterol-dependent

21 January 2018

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Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits

21 January 2018

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Inhibitors of amyloid β-protein aggregation mediated by GM1-containing raft-like membranes

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JNR.22796

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11 September 2017

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