(Q39428504)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22170088%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Thymoquinone reduces migration and invasion of human glioblastoma cells associated with FAK, MMP-2 and MMP-9 down-regulation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22170088%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

4

1 reference

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18 January 2020

author name string

Kaouther Kolli-Bouhafs

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22170088%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Abdelaziz Boukhari

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22170088%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Abdurazzag Abusnina

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22170088%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Jean-Pierre Gies

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22170088%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Claire Lugnier

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22170088%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Philippe Rondé

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22170088%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

publication date

15 December 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22170088%20AND%20SRC:MED&resulttype=core&format=json

Investigational New Drugs

18 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22170088%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22170088%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22170088%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

2121-2131

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22170088%20AND%20SRC:MED&resulttype=core&format=json

Glioblastoma therapy: going beyond Hercules Columns.

18 January 2020

cites work

1 reference

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Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma

21 January 2018

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Signal transduction by focal adhesion kinase in cancer

21 January 2018

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Control of motile and invasive cell phenotypes by focal adhesion kinase.

21 January 2018

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High focal adhesion kinase expression in invasive breast carcinomas is associated with an aggressive phenotype

21 January 2018

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Focal adhesion kinase expression in human neuroblastoma: immunohistochemical and real-time PCR analyses

21 January 2018

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Herbal medicine and cancer: an introductory overview

21 January 2018

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Thymoquinone: a promising anti-cancer drug from natural sources

21 January 2018

1 reference

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Review on molecular and therapeutic potential of thymoquinone in cancer

21 January 2018

1 reference

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Thymoquinone reduces mouse colon tumor cell invasion and inhibits tumor growth in murine colon cancer models

21 January 2018

1 reference

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Thymoquinone and cisplatin as a therapeutic combination in lung cancer: In vitro and in vivo

21 January 2018

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Thymoquinone inhibits tumor angiogenesis and tumor growth through suppressing AKT and extracellular signal-regulated kinase signaling pathways

21 January 2018

1 reference

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Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling

21 January 2018

1 reference

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Thymoquinone induces telomere shortening, DNA damage and apoptosis in human glioblastoma cells

21 January 2018

1 reference

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Mechanism of calcium oscillations in migrating human astrocytoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

Effects of thymoquinone on isolated and cellular proteasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

siRNA targeted against HAb18G/CD147 inhibits MMP-2 secretion, actin and FAK expression in hepatocellular carcinoma cell line via ERK1/2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

A role for focal adhesion kinase signaling in tumor necrosis factor-alpha-dependent matrix metalloproteinase-9 production in a cholangiocarcinoma cell line, CCKS1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

FAK signaling in neoplastic disorders: a linkage between inflammation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

Thymoquinone induces apoptosis through activation of caspase-8 and mitochondrial events in p53-null myeloblastic leukemia HL-60 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly

21 January 2018

1 reference

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Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions

21 January 2018

1 reference

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Focal adhesion kinase: the first ten years

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

Differential expression of protease activated receptor 1 (Par1) and pY397FAK in benign and malignant human ovarian tissue samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

Expression of focal adhesion kinase and phosphorylated focal adhesion kinase in squamous cell carcinoma of the larynx

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

Regulation of focal adhesion dynamics and disassembly by phosphorylation of FAK at tyrosine 397.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

Identification of Src-specific phosphorylation site on focal adhesion kinase: dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

FAK phosphorylation at Tyr-925 regulates cross-talk between focal adhesion turnover and cell protrusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

Mutation of Y925F in focal adhesion kinase (FAK) suppresses melanoma cell proliferation and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

Effects of thymoquinone in the expression of mucin 4 in pancreatic cancer cells: implications for the development of novel cancer therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

Studies on molecular mechanisms of growth inhibitory effects of thymoquinone against prostate cancer cells: role of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

Direct interaction of the N-terminal domain of focal adhesion kinase with the N-terminal transactivation domain of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

Post-translational modifications of PTEN and their potential therapeutic implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

Shc and FAK differentially regulate cell motility and directionality modulated by PTEN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

Calcium oscillations trigger focal adhesion disassembly in human U87 astrocytoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

Angiopoietin 2 induces glioma cell invasion by stimulating matrix metalloprotease 2 expression through the alphavbeta1 integrin and focal adhesion kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

Suppression of invasion in human U87 glioma cells by adenovirus-mediated co-transfer of TIMP-2 and PTEN gene

21 January 2018

1 reference

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Matrix metalloproteinase inhibitors: applications in oncology.

21 January 2018

1 reference

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Role of hyaluronan in glioma invasion

21 January 2018

1 reference

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Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

21 January 2018

1 reference

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Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9777-3

Mechanisms of glioma invasion: role of matrix-metalloproteinases

21 January 2018

1 reference

12 December 2020

FAK signaling in anaplastic astrocytoma and glioblastoma tumors

1 reference

12 December 2020

Oral and intraperitoneal LD50 of thymoquinone, an active principle of Nigella sativa, in mice and rats.

1 reference

12 December 2020

In vitro inhibition of growth and induction of apoptosis in cancer cell lines by thymoquinone.

1 reference

12 December 2020

Focal adhesion kinase enhances signaling through the Shc/extracellular signal-regulated kinase pathway in anaplastic astrocytoma tumor biopsy samples

1 reference

12 December 2020

From here to eternity - the secret of Pharaohs: Therapeutic potential of black cumin seeds and beyond.

1 reference

12 December 2020

Overexpression of focal adhesion kinase in primary colorectal carcinomas and colorectal liver metastases: immunohistochemistry and real-time PCR analyses

1 reference

12 December 2020

Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism.

1 reference

12 December 2020

PTEN-independent induction of caspase-mediated cell death and reduced invasion by the focal adhesion targeting domain (FAT) in human astrocytic brain tumors which highly express focal adhesion kinase (FAK)

1 reference

12 December 2020

The antitumor activity of thymoquinone and thymohydroquinone in vitro and in vivo

1 reference

12 December 2020

10.1007/S10637-011-9777-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22170088%20AND%20SRC:MED&resulttype=core&format=json

release_wzpq5345i5azxp2gzjrkubeu7i

18 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/wzpq5345i5azxp2gzjrkubeu7i

24 November 2022

mapped directly with Wikidata item

1 reference