(Q39429690)

11 September 2017

title

Β-elemene inhibits Hsp90/Raf-1 molecular complex inducing apoptosis of glioblastoma cells (English)

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11 September 2017

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Yong-Shun Zhao

1

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11 September 2017

Ting-Zhun Zhu

2

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11 September 2017

Yan-Wei Chen

3

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11 September 2017

Yi-Qun Yao

4

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11 September 2017

Chun-Ming Wu

5

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11 September 2017

Zhen-Qing Wei

6

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11 September 2017

Wei Wang

7

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11 September 2017

Ying-Hui Xu

8

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11 September 2017

publication date

11 December 2011

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Journal of Neuro-Oncology

11 September 2017

published in

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11 September 2017

volume

107

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11 September 2017

issue

2

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11 September 2017

page(s)

307-314

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Glioblastoma multiforme: a review of where we have been and where we are going

11 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0770-7

Antiproliferative effect of beta-elemene in chemoresistant ovarian carcinoma cells is mediated through arrest of the cell cycle at the G2-M phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0770-7

Synthesis and in vitro anti-proliferative activity of beta-elemene monosubstituted derivatives in HeLa cells mediated through arrest of cell cycle at the G1 phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0770-7

N-(beta-Elemene-13-yl)tryptophan methyl ester induces apoptosis in human leukemia cells and synergizes with arsenic trioxide through a hydrogen peroxide dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0770-7

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0770-7

Conferring specificity on the ubiquitous Raf/MEK signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0770-7

Coordinating ERK/MAPK signalling through scaffolds and inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0770-7

Constitutive activation of Raf-1 induces glioma formation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0770-7

p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0770-7

Disruption of the Raf-1-Hsp90 Molecular Complex Results in Destabilization of Raf-1 and Loss of Raf-1-Ras Association

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0770-7

The effect of megestrol acetate on growth of HepG2 cells in vitro and in vivo.

21 January 2018

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A pivotal role for ERK in the oncogenic behaviour of malignant melanoma?

21 January 2018

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Mechanisms of regulating the Raf kinase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0770-7

Molecular chaperones in cellular protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0770-7

Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0770-7

The basal flux of Akt in the mitochondria is mediated by heat shock protein 90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0770-7

21 January 2018

Heat shock protein 90.

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0770-7

Heat shock protein 90 as a molecular target for cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0770-7

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0770-7

Combination of all-trans retinoic acid and interferon-gamma suppressed PI3K/Akt survival pathway in glioblastoma T98G cells whereas NF-kappaB survival signaling in glioblastoma U87MG cells for induction of apoptosis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11060-011-0770-7

Mitochondria: regulating the inevitable.

21 January 2018

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The Bcl-2 protein family: arbiters of cell survival

21 January 2018

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The phosphorylation status and anti-apoptotic activity of Bcl-2 are regulated by ERK and protein phosphatase 2A on the mitochondria

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11060-011-0770-7

21 January 2018

1 reference

12 December 2020

[Experimental study on apoptosis induced by elemene in glioma cells]

1 reference

12 December 2020

Glioblastoma Multiforme Oncogenomics and Signaling Pathways

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12 December 2020

Anti-tumor effect of beta-elemene in glioblastoma cells depends on p38 MAPK activation

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12 December 2020

Hsp90 inhibitors: clinical development and future opportunities in oncology therapy.

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12 December 2020

Effect of traditional Chinese medicine on quality of life and survival period in patients with progressive gastric cancer

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12 December 2020

In vitro combination characterization of the new anticancer plant drug beta-elemene with taxanes against human lung carcinoma.

1 reference

12 December 2020

beta-elemene induces apoptosis of K562 leukemia cells

1 reference

12 December 2020

10.1007/S11060-011-0770-7

Identifiers

DOI

1 reference

11 September 2017

1 reference