(Q39441263)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094587%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Silencing of ETV6/RUNX1 abrogates PI3K/AKT/mTOR signaling and impairs reconstitution of leukemia in xenografts (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094587%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

1 reference

10

1 reference

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16 January 2020

author name string

G Fuka

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094587%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

H-P Kantner

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094587%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

R Grausenburger

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094587%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

A Inthal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094587%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

E Bauer

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094587%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

G Krapf

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094587%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

U Kaindl

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094587%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

M Kauer

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094587%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

M N Dworzak

9

1 reference

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16 January 2020

O A Haas

11

1 reference

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16 January 2020

R Panzer-Grümayer

12

1 reference

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16 January 2020

publication date

18 November 2011

1 reference

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16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094587%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

26

1 reference

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16 January 2020

issue

5

1 reference

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16 January 2020

page(s)

927-933

1 reference

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https://scigraph.springernature.com/pub.10.1038/leu.2011.322

16 January 2020

exact match

0 references

cites work

Acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

ETV6/RUNX1-positive relapses evolve from an ancestral clone and frequently acquire deletions of genes implicated in glucocorticoid signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Late relapses evolve from slow-responding subclones in t(12;21)-positive acute lymphoblastic leukemia: evidence for the persistence of a preleukemic clone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Chromosome translocations and covert leukemic clones are generated during normal fetal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

RNAi-mediated silencing of TEL/AML1 reveals a heat-shock protein- and survivin-dependent mechanism for survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Five distinct biological processes and 14 differentially expressed genes characterize TEL/AML1-positive leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Molecular signatures in childhood acute leukemia and their correlations to expression patterns in normal hematopoietic subpopulations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Classification of pediatric acute lymphoblastic leukemia by gene expression profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Differential expression of TCL1 during pre-B-cell acute lymphoblastic leukemia progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Role of the erythropoietin receptor in ETV6/RUNX1-positive acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

RNA interference as a potential tool in the treatment of leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Bioconductor: open software development for computational biology and bioinformatics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Exogenous cdk4 overcomes reduced cdk4 RNA and inhibition of G1 progression in hematopoietic cells expressing a dominant-negative CBF - a model for overcoming inhibition of proliferation by CBF oncoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Expression of the AML-1 oncogene shortens the G(1) phase of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

AML1 stimulates G1 to S progression via its transactivation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

ETV6/RUNX1 abrogates mitotic checkpoint function and targets its key player MAD2L1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Regulation of ribosomal S6 kinase 2 by mammalian target of rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Gene expression patterns associated with recurrent chromosomal translocations in acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

The leukemia-specific fusion gene ETV6/RUNX1 perturbs distinct key biological functions primarily by gene repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Trisomic dose of several chromosome 21 genes perturbs haematopoietic stem and progenitor cell differentiation in Down's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Oncogenic signaling from the hematopoietic growth factor receptors c-Kit and Flt3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Gene array analysis reveals a common Runx transcriptional programme controlling cell adhesion and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Translocation t(12;21) is related to in vitro cellular drug sensitivity to doxorubicin and etoposide in childhood acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Oncogene addiction versus oncogene amnesia: perhaps more than just a bad habit?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Revealing the role of TEL/AML1 for leukemic cell survival by RNAi-mediated silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Acute myeloid leukemia induced by MLL-ENL is cured by oncogene ablation despite acquisition of complex genetic abnormalities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Targeting MLL-AF4 with short interfering RNAs inhibits clonogenicity and engraftment of t(4;11)-positive human leukemic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Leukemic fusion genes MLL/AF4 and AML1/MTG8 support leukemic self-renewal by controlling expression of the telomerase subunit TERT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Genetic variegation of clonal architecture and propagating cells in leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

Immunogenotype changes prevail in relapses of young children with TEL-AML1-positive acute lymphoblastic leukemia and derive mainly from clonal selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

inferred from DOI database lookup

7 January 2021

based on heuristic

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.322

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/LEU.2011.322

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094587%20AND%20SRC:MED&resulttype=core&format=json

release_op2bo5xw5vfdfdg2pau3vomh44

16 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/op2bo5xw5vfdfdg2pau3vomh44

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference