(Q39441767)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22090514%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Authentically phosphorylated α-synuclein at Ser129 accelerates neurodegeneration in a rat model of familial Parkinson's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22090514%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

0 references

1 reference

1 reference

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Hiroyasu Sato

1

1 reference

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16 January 2020

Shigeki Arawaka

2

1 reference

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16 January 2020

Susumu Hara

3

1 reference

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16 January 2020

Shingo Fukushima

4

1 reference

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16 January 2020

Kaori Koga

5

1 reference

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16 January 2020

Shingo Koyama

6

1 reference

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16 January 2020

Takeo Kato

7

1 reference

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16 January 2020

language of work or name

English

0 references

publication date

1 November 2011

1 reference

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16 January 2020

published in

Journal of Neuroscience

1 reference

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16 January 2020

volume

31

1 reference

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16 January 2020

issue

46

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16 January 2020

page(s)

16884-16894

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describes a project that uses

16 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6633319/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield

1 reference

12 December 2020

Constitutive phosphorylation of the Parkinson's disease associated alpha-synuclein

1 reference

12 December 2020

Synucleins are a novel class of substrates for G protein-coupled receptor kinases

1 reference

12 December 2020

Clinical and pathological features of a Parkinsonian syndrome in a family with an Ala53Thr alpha-synuclein mutation

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12 December 2020

Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease.

1 reference

12 December 2020

Distribution of G-protein-coupled receptor kinase (GRK) isoforms 2, 3, 5 and 6 mRNA in the rat brain

1 reference

12 December 2020

alpha-Synuclein is phosphorylated in synucleinopathy lesions

1 reference

12 December 2020

Endogenous G protein-coupled receptor kinase 6 Regulates M3 muscarinic acetylcholine receptor phosphorylation and desensitization in human SH-SY5Y neuroblastoma cells

1 reference

12 December 2020

Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.

1 reference

12 December 2020

Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease

1 reference

12 December 2020

Concurrence of alpha-synuclein and tau brain pathology in the Contursi kindred

1 reference

12 December 2020

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

1 reference

12 December 2020

Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors

1 reference

12 December 2020

Promoters and regulatory elements that improve adeno-associated virus transgene expression in the brain

1 reference

12 December 2020

Ubiquitination of alpha-synuclein in Lewy bodies is a pathological event not associated with impairment of proteasome function

1 reference

12 December 2020

Caught in the act: alpha-synuclein is the culprit in Parkinson's disease

1 reference

12 December 2020

Mechanism of prion propagation: amyloid growth occurs by monomer addition

1 reference

12 December 2020

Viral vector mediated overexpression of human alpha-synuclein in the nigrostriatal dopaminergic neurons: a new model for Parkinson's disease.

1 reference

12 December 2020

Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease

1 reference

12 December 2020

Efficient selection for high-expression transfectants with a novel eukaryotic vector

1 reference

12 December 2020

Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease

1 reference

12 December 2020

The role of G-protein-coupled receptor kinase 5 in pathogenesis of sporadic Parkinson's disease.

1 reference

12 December 2020

Mechanisms of Parkinson's disease linked to pathological alpha-synuclein: new targets for drug discovery

1 reference

12 December 2020

The effect of truncated human alpha-synuclein (1-120) on dopaminergic cells in a transgenic mouse model of Parkinson's disease

1 reference

12 December 2020

The phosphorylation state of Ser-129 in human alpha-synuclein determines neurodegeneration in a rat model of Parkinson disease

1 reference

12 December 2020

Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of alpha-synuclein.

1 reference

12 December 2020

Polo-like kinase 2 (PLK2) phosphorylates alpha-synuclein at serine 129 in central nervous system

1 reference

12 December 2020

Phosphorylation does not prompt, nor prevent, the formation of alpha-synuclein toxic species in a rat model of Parkinson's disease

1 reference

12 December 2020

alpha-Synuclein and neuronal cell death

1 reference

12 December 2020

Human alpha-iduronidase gene transfer mediated by adeno-associated virus types 1, 2, and 5 in the brain of nonhuman primates: vector diffusion and biodistribution

1 reference

12 December 2020

Contribution of endogenous G-protein-coupled receptor kinases to Ser129 phosphorylation of alpha-synuclein in HEK293 cells.

1 reference

12 December 2020

Alpha-synuclein S129 phosphorylation mutants do not alter nigrostriatal toxicity in a rat model of Parkinson disease

1 reference

12 December 2020

Tyrosine and serine phosphorylation of alpha-synuclein have opposing effects on neurotoxicity and soluble oligomer formation

1 reference

12 December 2020

Phosphorylation of synucleins by members of the Polo-like kinase family

1 reference

12 December 2020

Serine 129 phosphorylation reduces the ability of alpha-synuclein to regulate tyrosine hydroxylase and protein phosphatase 2A in vitro and in vivo.

1 reference

12 December 2020

Genetic animal models of Parkinson's disease

1 reference

12 December 2020

Phosphorylated alpha-synuclein at Ser-129 is targeted to the proteasome pathway in a ubiquitin-independent manner

1 reference

12 December 2020

Enhanced phosphatase activity attenuates α-synucleinopathy in a mouse model

1 reference

12 December 2020

Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion

1 reference

12 December 2020

The hepatitis B virus posttranscriptional regulatory element is composed of two subelements

1 reference

12 December 2020

Alpha-synuclein in Lewy bodies

1 reference

12 December 2020

Molecular cloning of rat G-protein-coupled receptor kinase 6 (GRK6) from brain tissue, and its mRNA expression in different brain regions and peripheral tissues

1 reference

12 December 2020

Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats

1 reference

12 December 2020

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.

1 reference

12 December 2020

10.1523/JNEUROSCI.3967-11.2011

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22090514%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22090514%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference