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p53 modulates acquired resistance to EGFR inhibitors and radiation.
scientific article
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3229180
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22068033%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
title
p53 modulates acquired resistance to EGFR inhibitors and radiation
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3229180
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22068033%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
author
Sergi Benavente
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
3229180
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22068033%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
author name string
Shyhmin Huang
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3229180
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22068033%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
Eric A Armstrong
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
3229180
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22068033%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
Chunrong Li
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
3229180
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22068033%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
Deric L Wheeler
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMCID
3229180
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22068033%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
Paul M Harari
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMCID
3229180
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22068033%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
language of work or name
English
0 references
publication date
8 November 2011
1 reference
stated in
Europe PubMed Central
PMCID
3229180
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22068033%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
published in
Cancer Research
1 reference
stated in
Europe PubMed Central
PMCID
3229180
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22068033%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
volume
71
1 reference
stated in
Europe PubMed Central
PMCID
3229180
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22068033%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
page(s)
7071-7079
1 reference
stated in
Europe PubMed Central
PMCID
3229180
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22068033%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
issue
22
1 reference
stated in
Europe PubMed Central
PMCID
3229180
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22068033%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
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Two phases of mitogenic signaling unveil roles for p53 and EGR1 in elimination of inconsistent growth signals
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Understanding resistance to EGFR inhibitors-impact on future treatment strategies
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Oncogenic mutant forms of EGFR: lessons in signal transduction and targets for cancer therapy
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Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival
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The association between the T309G polymorphism of the MDM2 gene and sensitivity to anticancer drug is dependent on the p53 mutational status in cellular models.
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TP53 mutations predict disease control in metastatic colorectal cancer treated with cetuximab-based chemotherapy
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Targeting p53 for enhanced radio- and chemo-sensitivity.
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12 September 2017
Recent advances in p53 research: an interdisciplinary perspective.
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12 September 2017
Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer
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EGFR antagonists in cancer treatment
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12 September 2017
Biology of interactions: antiepidermal growth factor receptor agents
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12 September 2017
Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database
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Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
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12 September 2017
Restoration of p53 function leads to tumour regression in vivo
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Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.
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p53 and disease: when the guardian angel fails
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229180
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12 September 2017
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229180
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12 September 2017
The epidermal growth factor receptor as a target for cancer therapy
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12 September 2017
Mutant p53 initiates a feedback loop that involves Egr-1/EGF receptor/ERK in prostate cancer cells
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p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas
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Resistance to Targeted Therapies: Refining Anticancer Therapy in the Era of Molecular Oncology
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14 September 2017
P53 and PTEN expression contribute to the inhibition of EGFR downstream signaling pathway by cetuximab.
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14 September 2017
An epidermal growth factor inhibitor, Gefitinib, induces apoptosis through a p53-dependent upregulation of pro-apoptotic molecules and downregulation of anti-apoptotic molecules in human lung adenocarcinoma A549 cells
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PubMed Central
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14 September 2017
Mechanisms of acquired resistance to cetuximab: role of HER (ErbB) family members
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14 September 2017
Mitogen-activated protein kinase kinase inhibition enhances nuclear proapoptotic function of p53 in acute myelogenous leukemia cells
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229180
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14 September 2017
p53 enhances gefitinib-induced growth inhibition and apoptosis by regulation of Fas in non-small cell lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229180
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14 September 2017
Identification and validation of differences in protein levels in normal, premalignant, and malignant lung cells and tissues using high-throughput Western Array and immunohistochemistry
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229180
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14 September 2017
EGFR blockade by cetuximab alone or as combination therapy for growth control of hepatocellular cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229180
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14 September 2017
Antiviral agent Cidofovir restores p53 function and enhances the radiosensitivity in HPV-associated cancers.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229180
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25 September 2017
Tetracycline repressor, tetR, rather than the tetR-mammalian cell transcription factor fusion derivatives, regulates inducible gene expression in mammalian cells
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25 September 2017
Clinical definition of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229180
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17 June 2018
DNA mismatch repair and p53 function are major determinants of the rate of development of cisplatin resistance
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229180
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17 June 2018
Involvement of p53 and Raf/MEK/ERK pathways in hematopoietic drug resistance
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229180
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21 August 2018
Molecular alterations in tumors and response to combination chemotherapy with gefitinib for advanced colorectal cancer
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229180
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21 August 2018
p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229180
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21 August 2018
p53 gene mutations in non-small-cell lung cancer cell lines and their correlation with the presence of ras mutations and clinical features
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22068033
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1158/0008-5472.CAN-11-0128
1 reference
stated in
Europe PubMed Central
PMCID
3229180
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22068033%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
PMCID
3229180
1 reference
stated in
Europe PubMed Central
PMCID
3229180
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22068033%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
PubMed ID
22068033
1 reference
stated in
Europe PubMed Central
PMCID
3229180
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22068033%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
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