(Q39454848)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22017484%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Description of the constitutive activity of cloned human melatonin receptors hMT(1) and hMT(2) and discovery of inverse agonists (English)

1 reference

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15 January 2020

0 references

5

1 reference

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15 January 2020

Jean A Boutin

8

1 reference

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15 January 2020

7

Benoît Malpaux

1 reference

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15 January 2020

author name string

Séverine Devavry

1

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15 January 2020

Céline Legros

2

1 reference

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15 January 2020

Chantal Brasseur

3

1 reference

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15 January 2020

Philippe Delagrange

4

1 reference

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15 January 2020

William Cohen

6

1 reference

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15 January 2020

Olivier Nosjean

9

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15 January 2020

publication date

24 October 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22017484%20AND%20SRC:MED&resulttype=core&format=json

Journal of Pineal Research

15 January 2020

published in

1 reference

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15 January 2020

volume

53

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15 January 2020

issue

1

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15 January 2020

page(s)

29-37

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Molecular tools to study melatonin pathways and actions.

15 January 2020

cites work

1 reference

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Melatonin receptors, heterodimerization, signal transduction and binding sites: what's new?

21 January 2018

1 reference

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International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, classification, and pharmacology of G protein-coupled melatonin receptors

21 January 2018

1 reference

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Molecular pharmacology, regulation and function of mammalian melatonin receptors

21 January 2018

1 reference

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Dual coupling of MT(1) and MT(2) melatonin receptors to cyclic AMP and phosphoinositide signal transduction cascades and their regulation following melatonin exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Rhythmic gene expression in pituitary depends on heterologous sensitization by the neurohormone melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Physiological exposure to melatonin supersensitizes the cyclic adenosine 3',5'-monophosphate-dependent signal transduction cascade in Chinese hamster ovary cells expressing the human mt1 melatonin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Melatonin receptors in the eye: location, second messengers and role in ocular physiology

21 January 2018

1 reference

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Melatonin mt1 and MT2 receptors stimulate c-Jun N-terminal kinase via pertussis toxin-sensitive and -insensitive G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Melatonin induction of filamentous structures in non-neuronal cells that is dependent on expression of the human mt1 melatonin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

The Mel1a melatonin receptor is coupled to parallel signal transduction pathways

21 January 2018

1 reference

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Melatonin inhibits nitric oxide production by microvascular endothelial cells in vivo and in vitro.

21 January 2018

1 reference

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Monitoring of ligand-independent dimerization and ligand-induced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Preferential formation of MT1/MT2 melatonin receptor heterodimers with distinct ligand interaction properties compared with MT2 homodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Are G protein-coupled receptor heterodimers of physiological relevance?--Focus on melatonin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Constitutively active melatonin MT(1) receptors in male rat caudal arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Inverse agonist exposure enhances ligand binding and G protein activation of the human MT1 melatonin receptor, but leads to receptor down-regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Allosteric GPCR modulators: taking advantage of permissive receptor pharmacology.

21 January 2018

1 reference

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Functional selectivity through protean and biased agonism: who steers the ship?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Collateral efficacy in drug discovery: taking advantage of the good (allosteric) nature of 7TM receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Synthesis, enantiomeric resolution, and structure-activity relationship study of a series of 10,11-dihydro-5H-dibenzo[a,d]cycloheptene MT2 receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

New selective ligands of human cloned melatonin MT1 and MT2 receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Molecular cloning and pharmacological characterization of rat melatonin MT1 and MT2 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Molecular pharmacology of the ovine melatonin receptor: comparison with recombinant human MT1 and MT2 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

The end of a myth: cloning and characterization of the ovine melatonin MT(2) receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

High constitutive activity of native H3 receptors regulates histamine neurons in brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Constitutive activity of the histamine H3 receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Melatonin receptor signaling: finding the path through the dark

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Molecular organization and dynamics of the melatonin MT₁ receptor/RGS20/G(i) protein complex reveal asymmetry of receptor dimers for RGS and G(i) coupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Evaluation of cellular dielectric spectroscopy, a whole-cell, label-free technology for drug discovery on Gi-coupled GPCRs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Cellular dielectric spectroscopy: a label-free comprehensive platform for functional evaluation of endogenous receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

The functional role of cysteines adjacent to the NRY motif of the human MT1 melatonin receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Functional melatonin receptors in rat ovaries at various stages of the estrous cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Ligand efficacy and potency at recombinant human MT2 melatonin receptors: evidence for agonist activity of some mt1-antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Functional selectivity in GPCR modulator screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Inverse agonist activities of beta-adrenoceptor antagonists in rat myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

Functional evidence of inverse agonism in vascular smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00968.X

10.1111/J.1600-079X.2011.00968.X

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22017484%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference