(Q39457273)

12 September 2017

title

Huperzine A alleviates synaptic deficits and modulates amyloidogenic and nonamyloidogenic pathways in APPswe/PS1dE9 transgenic mice (English)

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12 September 2017

Ying Wang

1

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12 September 2017

Xi Can Tang

series ordinal

2

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12 September 2017

Hai Yan Zhang

series ordinal

3

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12 September 2017

publication date

17 October 2011

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Journal of Neuroscience Research

12 September 2017

published in

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12 September 2017

volume

90

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12 September 2017

issue

2

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12 September 2017

page(s)

508-517

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Interleukin-1alpha stimulates non-amyloidogenic pathway by alpha-secretase (ADAM-10 and ADAM-17) cleavage of APP in human astrocytic cells involving p38 MAP kinase.

12 September 2017

cites work

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21 January 2018

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21 January 2018

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Huperzine A regulates amyloid precursor protein processing via protein kinase C and mitogen-activated protein kinase pathways in neuroblastoma SK-N-SH cells over-expressing wild type human amyloid precursor protein 695.

21 January 2018

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L-3-n-butylphthalide regulates amyloid precursor protein processing by PKC and MAPK pathways in SK-N-SH cells over-expressing wild type human APP695.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Effects of huperzine A on secretion of nerve growth factor in cultured rat cortical astrocytes and neurite outgrowth in rat PC12 cells

21 January 2018

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Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches.

21 January 2018

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Huperzine A activates Wnt/β-catenin signaling and enhances the nonamyloidogenic pathway in an Alzheimer transgenic mouse model

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation

21 January 2018

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Involvement of M1-muscarinic acetylcholine receptors, protein kinase C and mitogen-activated protein kinase in the effect of huperzine A on secretory amyloid precursor protein-alpha

21 January 2018

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Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

21 January 2018

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Low-density lipoprotein receptor-related protein promotes amyloid precursor protein trafficking to lipid rafts in the endocytic pathway.

21 January 2018

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Huperzine A in rat plasma and CSF following intranasal administration.

21 January 2018

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Huperzine A enhances the level of secretory amyloid precursor protein and protein kinase C-alpha in intracerebroventricular beta-amyloid-(1-40) infused rats and human embryonic kidney 293 Swedish mutant cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JNR.22775

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12 September 2017

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