(Q35084882)

English

Age-related loss of synaptophysin immunoreactive presynaptic boutons within the hippocampus of APP751SL, PS1M146L, and APP751SL/PS1M146L transgenic mice

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Europe PubMed Central

PubMed publication ID

6 August 2017

Age-related loss of synaptophysin immunoreactive presynaptic boutons within the hippocampus of APP751SL, PS1M146L, and APP751SL/PS1M146L transgenic mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Harry W M Steinbusch

6

object named as

Harry W M Steinbusch

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Europe PubMed Central

PubMed publication ID

6 August 2017

1

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Bart P F Rutten

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Bart P F Rutten

1

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Europe PubMed Central

PubMed publication ID

6 August 2017

Nicolien M Van der Kolk

2

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Europe PubMed Central

PubMed publication ID

6 August 2017

Stephanie Schafer

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Marc A M J van Zandvoort

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Thomas A Bayer

5

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Europe PubMed Central

PubMed publication ID

6 August 2017

Christoph Schmitz

7

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Europe PubMed Central

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6 August 2017

language of work or name

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publication date

1 July 2005

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Europe PubMed Central

PubMed publication ID

6 August 2017

The American Journal of Pathology

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Europe PubMed Central

PubMed publication ID

6 August 2017

167

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Europe PubMed Central

PubMed publication ID

6 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

161-173

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Design-based stereology in neuroscience

1 reference

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A modified beta-amyloid hypothesis: intraneuronal accumulation of the beta-amyloid peptide--the first step of a fatal cascade

1 reference

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Massive CA1/2 neuronal loss with intraneuronal and N-terminal truncated Abeta42 accumulation in a novel Alzheimer transgenic model

1 reference

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Deciphering the molecular basis of memory failure in Alzheimer's disease

1 reference

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The aging brain: morphomolecular senescence of cortical circuits

1 reference

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Identification of the role of presenilins beyond Alzheimer's disease

1 reference

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Potential role of presenilin-regulated signaling pathways in sporadic neurodegeneration.

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Selective vulnerability of dentate granule cells prior to amyloid deposition in PDAPP mice: digital morphometric analyses

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Presenilins in memory, Alzheimer's disease, and therapy

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Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease

1 reference

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Building a more perfect beast: APP transgenic mice with neuronal loss

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Synaptic pathology in Alzheimer's disease: a review of ultrastructural studies

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Neuronal and glial calcium signaling in Alzheimer's disease

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Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

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Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport

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8 July 2018

Synaptic plasticity in animal models of early Alzheimer's disease

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8 July 2018

PDAPP; YFP double transgenic mice: a tool to study amyloid-beta associated changes in axonal, dendritic, and synaptic structures

1 reference

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Capacitive calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein

1 reference

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8 July 2018

Presenilins and APP in neuritic and synaptic plasticity: implications for the pathogenesis of Alzheimer's disease

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Alzheimer's disease is a synaptic failure

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8 July 2018

Selective vulnerability of corticocortical and hippocampal circuits in aging and Alzheimer's disease

1 reference

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8 July 2018

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

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8 July 2018

Oxidative stress in synaptosomal proteins from mutant presenilin-1 knock-in mice: implications for familial Alzheimer's disease.

1 reference

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8 July 2018

NFAT signaling: choreographing the social lives of cells

1 reference

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8 July 2018

gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

1 reference

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8 July 2018

Neuron loss from the hippocampus of Alzheimer's disease exceeds extracellular neurofibrillary tangle formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603440

8 July 2018

Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility

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Structural complexity and functional diversity of endoplasmic reticulum Ca(2+) stores

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Alzheimer's disease and Abeta toxicity: from top to bottom

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Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

1 reference

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8 July 2018

Familial Alzheimer's disease presenilin-1 mutants potentiate cell cycle arrest

1 reference

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8 July 2018

Circuit-specific alterations in hippocampal synaptophysin immunoreactivity predict spatial learning impairment in aged rats.

1 reference

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8 July 2018

Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss

1 reference

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8 July 2018

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

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Microglia, amyloid and dementia in alzheimer disease. A correlative study.

1 reference

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Presenilin-1 forms complexes with the cadherin/catenin cell-cell adhesion system and is recruited to intercellular and synaptic contacts

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Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

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Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant mice

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1 reference

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Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

1 reference

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8 July 2018

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

1 reference

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8 July 2018

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603440

8 July 2018

Neurotrophic and neuroprotective effects of hAPP in transgenic mice

1 reference

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8 July 2018

Neurons bearing neurofibrillary tangles are responsible for selected synaptic deficits in Alzheimer's disease

1 reference

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A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease.

1 reference

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1 reference

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Immunohistochemical quantification of the synapse-related protein synaptophysin in Alzheimer disease

1 reference

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Alzheimer patients and Down patients: abnormal presynaptic terminals are related to cerebral preamyloid deposits.

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1 reference

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Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches.

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Alzheimer's disease proteins in cerebellar and hippocampal synapses during postnatal development and aging of the rat.

1 reference

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No alterations of hippocampal neuronal number and synaptic bouton number in a transgenic mouse model expressing the beta-cleaved C-terminal APP fragment

1 reference

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27 September 2018

Evidence that synaptically released beta-amyloid accumulates as extracellular deposits in the hippocampus of transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603440

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Nectin-1alpha, an immunoglobulin-like receptor involved in the formation of synapses, is a substrate for presenilin/gamma-secretase-like cleavage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603440

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Intraneuronal APP/A beta trafficking and plaque formation in beta-amyloid precursor protein and presenilin-1 transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603440

27 September 2018

Progressive reduction of synaptophysin message in single neurons in Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1603440

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Maintained synaptophysin immunoreactivity in Tg2576 transgenic mice during aging: correlations with cognitive impairment.

1 reference

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Early formation of mature amyloid-beta protein deposits in a mutant APP transgenic model depends on levels of Abeta(1-42).

1 reference

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In-vivo measurement of activated microglia in dementia

1 reference

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27 September 2018

Intraneuronal Abeta accumulation precedes plaque formation in beta-amyloid precursor protein and presenilin-1 double-transgenic mice

1 reference

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1 reference

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Neuroanatomical abnormalities in behaviorally characterized APP(V717F) transgenic mice.

1 reference

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27 September 2018

No loss of synaptic proteins in the hippocampus of aged, behaviorally impaired rats.

1 reference

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1 reference

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Cerebral amyloid induces aberrant axonal sprouting and ectopic terminal formation in amyloid precursor protein transgenic mice

1 reference

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27 September 2018

Quantitative decrease in synaptophysin message expression and increase in cathepsin D message expression in Alzheimer disease neurons containing neurofibrillary tangles

1 reference

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Hippocampal neuron and synaptophysin-positive bouton number in aging C57BL/6 mice

1 reference

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27 September 2018

Reorganization of cholinergic terminals in the cerebral cortex and hippocampus in transgenic mice carrying mutated presenilin-1 and amyloid precursor protein transgenes.

1 reference

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27 September 2018

Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2962963-X

7 January 2021

Time sequence of maturation of dystrophic neurites associated with Abeta deposits in APP/PS1 transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2962963-X

7 January 2021

Synaptotrophic effects of human amyloid β protein precursors in the cortex of transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2962963-X

7 January 2021

Enhanced production and oligomerization of the 42-residue amyloid beta-protein by Chinese hamster ovary cells stably expressing mutant presenilins

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2962963-X

7 January 2021

Loss of synaptophysin-like immunoreactivity in the hippocampal formation is an early phenomenon in Alzheimer's disease

1 reference

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7 January 2021

Identifiers

10.1016/S0002-9440(10)62963-X

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

ResearchGate publication ID

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