(Q39457949)

12 September 2017

Distinct roles of first exon variants of the tumor-suppressor Patched1 in Hedgehog signaling (English)

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12 September 2017

Peter G Zaphiropoulos

6

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12 September 2017

T Shimokawa

1

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12 September 2017

J Svärd

2

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12 September 2017

K Heby-Henricson

3

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12 September 2017

S Teglund

4

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12 September 2017

R Toftgård

5

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12 September 2017

language of work or name

English

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publication date

19 February 2007

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12 September 2017

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12 September 2017

26

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12 September 2017

34

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12 September 2017

4889-4896

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210301

12 September 2017

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cites work

Expression of the PTCH1 tumor suppressor gene is regulated by alternative promoters and a single functional Gli-binding site

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Eyes absent, a key repressor of polar cell fate during Drosophila oogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Genome-wide analysis of mammalian promoter architecture and evolution

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Characterization of two patched receptors for the vertebrate hedgehog protein family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Overlapping and distinct transcriptional regulator properties of the GLI1 and GLI2 oncogenes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Altered neural cell fates and medulloblastoma in mouse patched mutants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

A mammalian patched homolog is expressed in target tissues of sonic hedgehog and maps to a region associated with developmental abnormalities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Regulation of gene expression by alternative untranslated regions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Human homolog of patched, a candidate gene for the basal cell nevus syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Novel RNAs identified from an in-depth analysis of the transcriptome of human chromosomes 21 and 22

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Alternative first exons of PTCH1 are differentially regulated in vivo and may confer different functions to the PTCH1 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Patched2 modulates tumorigenesis in patched1 heterozygous mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Sonic Hedgehog Regulates Otic Capsule Chondrogenesis and Inner Ear Development in the Mouse Embryo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Ptch2, a second mouse Patched gene is co-expressed with Sonic hedgehog

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Identification and characterization of multiple isoforms of a murine and human tumor suppressor, patched, having distinct first exons.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Inhibition of GLI1 gene activation by Patched1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Distinct roles of PTCH2 splice variants in Hedgehog signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

A novel first exon of the Patched1 gene is upregulated by Hedgehog signaling resulting in a protein with pathway inhibitory functions.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Isolation and characterization of human patched 2 (PTCH2), a putative tumour suppressor gene inbasal cell carcinoma and medulloblastoma on chromosome 1p32.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

The effects of splice site mutations in patients with naevoid basal cell carcinoma syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

A potential role of alternative splicing in the regulation of the transcriptional activity of human GLI2 in gonadal tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Brain- and heart-specific Patched-1 containing exon 12b is a dominant negative isoform and is expressed in medulloblastomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Post-transcriptional regulation of the gli1 oncogene by the expression of alternative 5' untranslated regions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210301

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210301

1 reference

12 September 2017

1 reference