(Q39463391)

12 September 2017

title

Trans-sialidase from Trypanosoma brucei as a potential target for DNA vaccine development against African trypanosomiasis (English)

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12 September 2017

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African trypanosomiasis

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Marcelo Sousa Silva

1

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Jorge Atouguia

object named as

Jorge Atouguia

4

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Gabriel A. Monteiro

object named as

Gabriel Amaro Monteiro

5

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Duarte Miguel F Prazeres

object named as

Duarte Miguel F Prazeres

2

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author name string

Andreia Lança

3

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12 September 2017

publication date

7 July 2009

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12 September 2017

published in

Parasitology Research

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12 September 2017

volume

105

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12 September 2017

issue

5

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12 September 2017

page(s)

1223-1229

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DNA vaccines: progress and challenges

12 September 2017

cites work

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https://api.crossref.org/works/10.1007%2FS00436-009-1542-6

Trans-sialidase recombinant protein mixed with CpG motif-containing oligodeoxynucleotide induces protective mucosal and systemic trypanosoma cruzi immunity involving CD8+ CTL and B cell-mediated cross-priming.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-009-1542-6

Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-009-1542-6

The Induction of a Type 1 Immune Response following a Trypanosoma brucei Infection Is MyD88 Dependent

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FS00436-009-1542-6

21 January 2018

12 December 2020

A novel cell surface trans-sialidase of trypanosoma cruzi generates a stage-specific epitope required for invasion of mammalian cells

1 reference

12 December 2020

Comparison of antibody and protective immune responses against Trypanosoma cruzi infection elicited by immunization with a parasite antigen delivered as naked DNA or recombinant protein

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12 December 2020

Experimental murine Trypanosoma congolense infections. I. Administration of anti-IFN-gamma antibodies alters trypanosome-susceptible mice to a resistant-like phenotype.

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12 December 2020

Plasmid DNA and viral vector-based vaccines for the treatment of cancer

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12 December 2020

Genetic immunization elicits antigen-specific protective immune responses and decreases disease severity in Trypanosoma cruzi infection

1 reference

12 December 2020

Resistance to the African trypanosomes is IFN-gamma dependent.

1 reference

12 December 2020

Procyclic Trypanosoma brucei expresses separate sialidase and trans-sialidase enzymes on its surface membrane

1 reference

12 December 2020

Interferon-gamma and interleukin-12 genes are preferentially expressed during early experimental African trypanosomiasis and suppressed by denervation of the spleen

1 reference

12 December 2020

Innate and acquired immunity in the pathogenesis of Chagas disease

1 reference

12 December 2020

Eliminating human African trypanosomiasis: where do we stand and what comes next?

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12 December 2020

The pathogenesis and modulation of the post-treatment reactive encephalopathy in a mouse model of Human African Trypanosomiasis

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12 December 2020

Post-treatment hind-leg paralysis in mice infected with Trypanosoma brucei brucei: a light microscopic study.

1 reference

12 December 2020

Combination chemotherapy of CNS trypanosomiasis

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12 December 2020

The trans-sialidase from the african trypanosome Trypanosoma brucei

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12 December 2020

Enzyme-linked immunoassay using recombinant trans-sialidase of Trypanosoma cruzi can be employed for monitoring of patients with Chagas' disease after drug treatment

1 reference

12 December 2020

CpG motifs in bacterial DNA trigger direct B-cell activation

1 reference

12 December 2020

Isolation of salivarian trypanosomes from man and other mammals using DEAE-cellulose.

1 reference

12 December 2020

Enhancement of DNA vaccine potency in rhesus macaques by electroporation

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12 December 2020

Circumventing genetic restriction of protection against malaria with multigene DNA immunization: CD8+ cell-, interferon gamma-, and nitric oxide-dependent immunity

1 reference

12 December 2020

Cytokines and the acute phase response in post-treatment reactive encephalopathy of Trypanosoma brucei brucei infected mice.

1 reference

12 December 2020

Bacterial DNA induces murine interferon-gamma production by stimulation of interleukin-12 and tumor necrosis factor-alpha

1 reference

12 December 2020

Rational drug design in parasitology: trans-sialidase as a case study for Chagas disease.

1 reference

12 December 2020

Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization

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12 December 2020

Interleukin-4-dependent immunoglobulin G1 isotype switch in the presence of a polarized antigen-specific Th1-cell response to the trypanosome variant surface glycoprotein.

1 reference

12 December 2020

Successful treatment of experimental murine Trypanosoma brucei infection with topical melarsoprol gel.

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12 December 2020

CD8+-T-cell-dependent control of Trypanosoma cruzi infection in a highly susceptible mouse strain after immunization with recombinant proteins based on amastigote surface protein 2.

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12 December 2020

The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents

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12 December 2020

Relative contribution of interferon-gamma and interleukin-10 to resistance to murine African trypanosomosis.

1 reference

12 December 2020

DNA vaccines to attack cancer

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12 December 2020

The preferential induction of a Th1 immune response by DNA-based immunization is mediated by the immunostimulatory effect of plasmid DNA

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12 December 2020

Trans-sialidase delivered as a naked DNA vaccine elicits an immunological response similar to a Trypanosoma cruzi infection

1 reference

12 December 2020

Further protection against antigenic drift of influenza virus in a ferret model by DNA vaccination

1 reference

12 December 2020

Immunization with a plasmid DNA containing the gene of trans-sialidase reduces Trypanosoma cruzi infection in mice

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12 December 2020

Purification of a cystic fibrosis plasmid vector for gene therapy using hydrophobic interaction chromatography

1 reference

12 December 2020

Trypanosoma cruzi trans-sialidase potentiates T cell activation through antigen-presenting cells: role of IL-6 and Bruton's tyrosine kinase

1 reference

12 December 2020

10.1007/S00436-009-1542-6

Identifiers

DOI

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12 September 2017

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