(Q39471425)

12 September 2017

title

Inhibition of the in vitro growth of Plasmodium falciparum by acyclic nucleoside phosphonates (English)

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12 September 2017

main subject

Plasmodium falciparum

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5

A Holý

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12 September 2017

6

J Balzarini

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12 September 2017

L Naesens

3

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author name string

L J Smeijsters

1

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12 September 2017

F F Franssen

2

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12 September 2017

E de Vries

4

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12 September 2017

E de Clercq

7

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12 September 2017

J P Overdulve

8

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12 September 2017

publication date

1 June 1999

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International Journal of Antimicrobial Agents

12 September 2017

published in

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12 September 2017

volume

12

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12 September 2017

issue

1

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12 September 2017

page(s)

53-61

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Purification and characterization of DNA polymerases from Plasmodium berghei

12 September 2017

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"The end of innocence" revisited: resistance of herpesviruses to antiviral drugs

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Inhibition of the growth of Plasmodium falciparum and Plasmodium berghei by the DNA polymerase inhibitor HPMPA.

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7 January 2021

Mechanism of uptake of the phosphonate analog (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in Vero cells

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7 January 2021

Cellular uptake of phosphonylmethoxyalkylpurine derivatives

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7 January 2021

Transport of 9-(2-phosphonomethoxyethyl)adenine across plasma membrane of HeLa S3 cells is protein mediated

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The movement of fluorescent endocytic tracers in Plasmodium falciparum infected erythrocytes

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7 January 2021

Ducts, channels and transporters in Plasmodium-infected erythrocytes

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Parasite-regulated membrane transport processes and metabolic control in malaria-infected erythrocytes

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Transport pathways in the malaria-infected erythrocyte. Their characterization and their use as potential targets for chemotherapy

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A membrane network for nutrient import in red cells infected with the malaria parasite

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7 January 2021

Direct access to serum macromolecules by intraerythrocytic malaria parasites

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Nutrient transport pathways in Plasmodium-infected erythrocytes: what and where are they?

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Antiviral agents: characteristic activity spectrum depending on the molecular target with which they interact.

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7 January 2021

Human cytomegalovirus UL97 open reading frame encodes a protein that phosphorylates the antiviral nucleoside analogue ganciclovir

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7 January 2021

A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells

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7 January 2021

Phosphorylation of 9-(2-phosphonomethoxyethyl)adenine and 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine by AMP(dAMP) kinase from L1210 cells

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7 January 2021

Metabolic pathways for activation of the antiviral agent 9-(2-phosphonylmethoxyethyl)adenine in human lymphoid cells

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7 January 2021

Intracellular metabolism and mechanism of anti-retrovirus action of 9-(2-phosphonylmethoxyethyl)adenine, a potent anti-human immunodeficiency virus compound

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7 January 2021

Enzymes of purine and pyrimidine metabolism from the human malaria parasite, Plasmodium falciparum

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7 January 2021

Metabolism and mechanism of antiretroviral action of purine and pyrimidine derivatives

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7 January 2021

Mechanism of action of acyclic nucleoside phosphonates against herpes virus replication.

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7 January 2021

K65R mutation of human immunodeficiency virus type 1 reverse transcriptase encodes cross-resistance to 9-(2-phosphonylmethoxyethyl)adenine

1 reference

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7 January 2021

A point mutation in the human cytomegalovirus DNA polymerase gene confers resistance to ganciclovir and phosphonylmethoxyalkyl derivatives

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7 January 2021

Intracellular metabolism and action of acyclic nucleoside phosphonates on DNA replication.

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7 January 2021

Effect of incorporation of cidofovir into DNA by human cytomegalovirus DNA polymerase on DNA elongation

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7 January 2021

The effect of (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl) adenine on nuclear and organellar DNA synthesis in erythrocytic schizogony in malaria.

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7 January 2021

Antimalarial and toxic effects of the acyclic nucleoside phosphonate (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine in Plasmodium berghei-infected mice.

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7 January 2021

An improved technique for the cultivation of Plasmodium falciparum in vitro without daily medium change

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7 January 2021

Synchronization of Plasmodium falciparum Erythrocytic Stages in Culture

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7 January 2021

Simple, fast, and accurate fluorometric method to determine drug susceptibility of Plasmodium falciparum in 24-well suspension cultures.

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7 January 2021

Metabolism and in vitro antiretroviral activities of bis(pivaloyloxymethyl) prodrugs of acyclic nucleoside phosphonates

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7 January 2021

1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl] cytosine, an intracellular prodrug for (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine with improved therapeutic index in vivo

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7 January 2021

Conversion of 1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl]cytosine to cidofovir by an intracellular cyclic CMP phosphodiesterase

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7 January 2021

Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine

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7 January 2021

Antiviral activity of phosphonylmethoxyalkyl derivatives of purine and pyrimidines

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7 January 2021

Broad-spectrum antiviral activity of the acyclic guanosine phosphonate (R,S)-HPMPG.

1 reference

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7 January 2021

Ganciclovir permeation of the human erythrocyte membrane

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7 January 2021

10.1016/S0924-8579(99)00003-5

Identifiers

DOI

1 reference

release_iafejrdwmnd77ltgmem54boa4e

12 September 2017

Fatcat ID

0 references

1 reference