(Q39479021)

12 September 2017

title

Inhibition of hepatitis C virus replication through adenosine monophosphate-activated protein kinase-dependent and -independent pathways (English)

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12 September 2017

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Kiyonao Sada

5

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author name string

Kenji Nakashima

1

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12 September 2017

Kenji Takeuchi

2

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12 September 2017

Kazuyasu Chihara

3

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12 September 2017

Hak Hotta

4

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12 September 2017

publication date

1 November 2011

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Microbiology and Immunology

12 September 2017

published in

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12 September 2017

volume

55

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12 September 2017

issue

11

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12 September 2017

page(s)

774-782

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The way forward in HCV treatment--finding the right path

12 September 2017

cites work

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Metabolic factors and subsequent risk of hepatocellular carcinoma by hepatitis virus infection status: a large-scale population-based cohort study of Japanese men and women (JPHC Study Cohort II).

21 January 2018

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High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C.

21 January 2018

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Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients.

21 January 2018

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Purification and characterization of the AMP-activated protein kinase. Copurification of acetyl-CoA carboxylase kinase and 3-hydroxy-3-methylglutaryl-CoA reductase kinase activities

21 January 2018

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5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?

21 January 2018

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Regulation of 5'-AMP-activated protein kinase activity by the noncatalytic beta and gamma subunits

21 January 2018

1 reference

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Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

21 January 2018

1 reference

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LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

21 January 2018

1 reference

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Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase

21 January 2018

1 reference

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Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

21 January 2018

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Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase

21 January 2018

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Identification by amino acid sequencing of three major regulatory phosphorylation sites on rat acetyl-CoA carboxylase

21 January 2018

1 reference

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Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis

21 January 2018

1 reference

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Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491.

21 January 2018

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HCV replication suppresses cellular glucose uptake through down-regulation of cell surface expression of glucose transporters

21 January 2018

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Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication

21 January 2018

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Efficient production of infectious hepatitis C virus with adaptive mutations in cultured hepatoma cells.

21 January 2018

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Hepatitis C virus NS5A protein interacts with and negatively regulates the non-receptor protein tyrosine kinase Syk.

21 January 2018

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Complete replication of hepatitis C virus in cell culture

21 January 2018

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Tyrosine phosphorylation of 3BP2 regulates B cell receptor-mediated activation of NFAT

21 January 2018

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Regulation of FcepsilonRI-mediated degranulation by an adaptor protein 3BP2 in rat basophilic leukemia RBL-2H3 cells

21 January 2018

1 reference

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Negative regulation of FcepsilonRI-mediated mast cell activation by a ubiquitin-protein ligase Cbl-b

21 January 2018

1 reference

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Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase

21 January 2018

1 reference

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The Enzymatic Synthesis of 5-Amino-4-Imidazolecarboxamide Riboside Triphosphate (ZTP)

21 January 2018

1 reference

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Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

21 January 2018

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Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2011.00382.X

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2011.00382.X

Hepatitis C Virus Down-Regulates Insulin Receptor Substrates 1 and 2 through Up-Regulation of Suppressor of Cytokine Signaling 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2011.00382.X

Clearance of HCV improves insulin resistance, beta-cell function, and hepatic expression of insulin receptor substrate 1 and 2.

21 January 2018

1 reference

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Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2011.00382.X

Pioglitazone treatment activates AMP-activated protein kinase in rat liver and adipose tissue in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2011.00382.X

Role of AMP-activated protein kinase in mechanism of metformin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2011.00382.X

The lipid droplet is an important organelle for hepatitis C virus production

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2011.00382.X

Anti-HCV activities of selective polyunsaturated fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2011.00382.X

Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2011.00382.X

Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2011.00382.X

Characterization of cell lines carrying self-replicating hepatitis C virus RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2011.00382.X

Replication of Hepatitis C Virus Subgenomes in Nonhepatic Epithelial and Mouse Hepatoma Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2011.00382.X

Metformin and reduced risk of hepatocellular carcinoma in diabetic patients with chronic liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2011.00382.X

Treatment of insulin resistance with metformin in naïve genotype 1 chronic hepatitis C patients receiving peginterferon alfa-2a plus ribavirin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1348-0421.2011.00382.X

10.1111/J.1348-0421.2011.00382.X

21 January 2018

Identifiers

DOI

1 reference

12 September 2017

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