(Q39488869)

English

HRAS mutants identified in Costello syndrome patients can induce cellular senescence: possible implications for the pathogenesis of Costello syndrome

scientific article

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

HRAS mutants identified in Costello syndrome patients can induce cellular senescence: possible implications for the pathogenesis of Costello syndrome (English)

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

0 references

Costello syndrome

1 reference

based on heuristic

inferred from title

cellular senescence

1 reference

based on heuristic

inferred from title

Yoshikazu Kuroki

13

object named as

Yoshikazu Kuroki

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

author name string

Tetsuya Niihori

1

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Yoko Aoki

2

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Nobuhiko Okamoto

3

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Kenji Kurosawa

4

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Hirofumi Ohashi

5

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Seiji Mizuno

6

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Hiroshi Kawame

7

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Johji Inazawa

8

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Toshihiro Ohura

9

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Hiroshi Arai

10

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Shin Nabatame

11

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Kiyoshi Kikuchi

12

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Masaru Miura

14

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Toju Tanaka

15

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Akira Ohtake

16

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Isaku Omori

17

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Kenji Ihara

18

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Hiroyo Mabe

19

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Kyoko Watanabe

20

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Shinichi Niijima

21

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Erika Okano

22

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Hironao Numabe

23

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Yoichi Matsubara

24

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

publication date

18 August 2011

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Journal of Human Genetics

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

56

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

707-715

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Costello syndrome: an overview

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

The RAS/MAPK syndromes: novel roles of the RAS pathway in human genetic disorders

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Germline mutations in HRAS proto-oncogene cause Costello syndrome

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

HRAS mutations in Costello syndrome: detection of constitutional activating mutations in codon 12 and 13 and loss of wild-type allele in malignancy.

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

HRAS mutation analysis in Costello syndrome: genotype and phenotype correlation.

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Genotype-phenotype correlation in Costello syndrome: HRAS mutation analysis in 43 cases.

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Recurring HRAS mutation G12S in Dutch patients with Costello syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

De novo HRAS and KRAS mutations in two siblings with short stature and neuro-cardio-facio-cutaneous features

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Mutation analysis in Costello syndrome: functional and structural characterization of the HRAS p.Lys117Arg mutation

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Severe, obstructive biventricular hypertrophy in a patient with Costello syndrome: Clinical impact and management.

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Mutation and phenotypic spectrum in patients with cardio-facio-cutaneous and Costello syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Duplication of Glu37 in the switch I region of HRAS impairs effector/GAP binding and underlies Costello syndrome by promoting enhanced growth factor-dependent MAPK and AKT activation

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Prenatal features of Costello syndrome: ultrasonographic findings and atrial tachycardia

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

A premature infant with Costello syndrome due to a rare G13C HRAS mutation.

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Myopathy caused by HRAS germline mutations: implications for disturbed myogenic differentiation in the presence of constitutive HRas activation

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Comparative biochemical properties of normal and activated human ras p21 protein

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Relationship among guanine nucleotide exchange, GTP hydrolysis, and transforming potential of mutated ras proteins

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Impact of cellular senescence signature on ageing research

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Suppressing cancer: the importance of being senescent.

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Further delineation of the behavioral and neurologic features in Costello syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

A case of Costello syndrome and glycogen storage disease type III.

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

High incidence of progressive postnatal cerebellar enlargement in Costello syndrome: brain overgrowth associated with HRAS mutations as the likely cause of structural brain and spinal cord abnormalities.

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Costello syndrome and hyperinsulinemic hypoglycemia.

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Expression of H-RASV12 in a zebrafish model of Costello syndrome causes cellular senescence in adult proliferating cells

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

The adult phenotype in Costello syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Biological properties of human c-Ha-ras1 genes mutated at codon 12.

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Analysis of the transforming potential of the human H-ras gene by random mutagenesis

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Effect of simvastatin on cognitive functioning in children with neurofibromatosis type 1: a randomized controlled trial

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Statins and cancer risk: a meta-analysis

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Senescence comes of age

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Costello syndrome: clinical diagnosis in the first year of life

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

Diversity, parental germline origin, and phenotypic spectrum of de novoHRASmissense changes in Costello syndrome

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

21 January 2018

The diagnosis of Costello syndrome: Nomenclature in Ras/MAPK pathway disorders

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

7 January 2021

based on heuristic

inferred from DOI database lookup

Further delineation of the phenotype resulting from BRAF or MEK1 germline mutations helps differentiate cardio-facio-cutaneous syndrome from Costello syndrome

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

7 January 2021

based on heuristic

inferred from DOI database lookup

Distal phalangeal creases--a distinctive dysmorphic feature in disorders of the RAS signalling pathway?

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

7 January 2021

based on heuristic

inferred from DOI database lookup

Costello syndrome associated with novel germline HRAS mutations: an attenuated phenotype?

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

7 January 2021

based on heuristic

inferred from DOI database lookup

Rapidly progressive scoliosis after successful treatment for osteopenia in Costello syndrome

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

7 January 2021

based on heuristic

inferred from DOI database lookup

Prenatal diagnosis of Costello syndrome using 3D ultrasonography amniocentesis confirmation of the rare HRAS mutation G12D

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

7 January 2021

based on heuristic

inferred from DOI database lookup

Male-to-male transmission of Costello syndrome: G12S HRAS germline mutation inherited from a father with somatic mosaicism

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

7 January 2021

based on heuristic

inferred from DOI database lookup

Recurring G12S mutation of HRAS in a Chinese child with Costello syndrome with high alkaline phosphatase level

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural differences between valine-12 and aspartate-12 Ras proteins may modify carcinoma aggression.

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

7 January 2021

based on heuristic

inferred from DOI database lookup

Medical and surgical perspectives of cardiac hypertrophy in Costello syndrome

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

7 January 2021

based on heuristic

inferred from DOI database lookup

Costello syndrome with growth hormone deficiency and hypoglycemia: a new report and review of the endocrine associations

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

7 January 2021

based on heuristic

inferred from DOI database lookup

Growth hormone deficiency in Costello syndrome

1 reference

https://api.crossref.org/works/10.1038%2FJHG.2011.85

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/JHG.2011.85

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q39488869&oldid=2273940325"