(Q39504522)

12 September 2017

title

Celebrating 30 years of Wnt signaling (English)

1 reference

12 September 2017

Folkert Verkaar

1

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12 September 2017

Ken M Cadigan

series ordinal

2

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12 September 2017

Renée van Amerongen

series ordinal

3

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12 September 2017

publication date

11 December 2012

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12 September 2017

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12 September 2017

volume

5

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12 September 2017

issue

254

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12 September 2017

page(s)

mr2

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Interpretation of the wingless gradient requires signaling-induced self-inhibition.

12 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Active Wnt proteins are secreted on exosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Membrane targeting of palmitoylated Wnt and Hedgehog revealed by chemical probes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Structural basis of Wnt recognition by Frizzled

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Monounsaturated fatty acid modification of Wnt protein: its role in Wnt secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Wnt proteins are lipid-modified and can act as stem cell growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Structural Basis of Wnt Signaling Inhibition by Dickkopf Binding to LRP5/6

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Structural and Functional Studies of LRP6 Ectodomain Reveal a Platform for Wnt Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

A new secreted protein that binds to Wnt proteins and inhibits their activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Augmented Wnt signaling in a mammalian model of accelerated aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

The Adenomatous polyposis coli tumour suppressor is essential for Axin complex assembly and function and opposes Axin's interaction with Dishevelled

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Dishevelled interacts with the DIX domain polymerization interface of Axin to interfere with its function in down-regulating β-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Reversible modification of adenomatous polyposis coli (APC) with K63-linked polyubiquitin regulates the assembly and activity of the β-catenin destruction complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Wnt/beta-catenin signaling: components, mechanisms, and diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Kinetic responses of β-catenin specify the sites of Wnt control

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Developmental stage and time dictate the fate of Wnt/β-catenin-responsive stem cells in the mammary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5⁺ stem cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Noncanonical Wnt signaling maintains hematopoietic stem cells in the niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Canonical wnt signaling regulates hematopoiesis in a dosage-dependent fashion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Metabolic trajectory of cellular differentiation in small intestine by Phasor Fluorescence Lifetime Microscopy of NADH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Proteomic analysis of beta-catenin activation in mouse liver by DIGE analysis identifies glucose metabolism as a new target of the Wnt pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Interactions between cancer stem cells and their niche govern metastatic colonization

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

New avenues to target Wnt/β-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Crystal structure of a Tankyrase-Axin complex and its implications for Axin turnover and Tankyrase substrate recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

Recognition of the iso-ADP-ribose moiety in poly(ADP-ribose) by WWE domains suggests a general mechanism for poly(ADP-ribosyl)ation-dependent ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003714

10.1126/SCISIGNAL.2003714

21 January 2018

Identifiers

DOI

1 reference

release_q2h7rn3jczh3xdazb6j4yhlydm

12 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/q2h7rn3jczh3xdazb6j4yhlydm

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference