(Q39508002)

English

The myo-1,2-Diaminocyclitol Scaffold Defines Potent Glucocerebrosidase Activators and Promising Pharmacological Chaperones for Gaucher Disease.

scientific article published on 18 May 2011

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scholarly article

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900357%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

The myo-1,2-Diaminocyclitol Scaffold Defines Potent Glucocerebrosidase Activators and Promising Pharmacological Chaperones for Gaucher Disease (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900357%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

molecular chaperones

0 references

Gaucher's disease

1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900357%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Amadeu Llebaria

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900357%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1

object named as

Ana Trapero

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Amadeu Llebaria

2

object named as

Amadeu Llebaria

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

18 May 2011

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900357%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

ACS Medicinal Chemistry Letters

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900357%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900357%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900357%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

614-619

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900357%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

New glucocerebrosidase inhibitors by exploration of chemical diversity of N-substituted aminocyclitols using click chemistry and in situ screening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017985

12 September 2017

The pharmacological chaperone isofagomine increases the activity of the Gaucher disease L444P mutant form of beta-glucosidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017985

12 September 2017

Treating lysosomal storage diseases with pharmacological chaperones: from concept to clinics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017985

12 September 2017

Enantio- and Diastereodivergent Synthetic Route to Multifarious Cyclitols from D-Xylose via Ring-Closing Metathesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017985

12 September 2017

Identification and characterization of ambroxol as an enzyme enhancement agent for Gaucher disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017985

12 September 2017

Molecular basis for beta-glucosidase inhibition by ring-modified calystegine analogues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017985

12 September 2017

Treating lysosomal storage disorders: current practice and future prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017985

12 September 2017

Pharmacologic chaperoning as a strategy to treat Gaucher disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017985

12 September 2017

The cell biology of lysosomal storage disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017985

12 September 2017

Chemical chaperones increase the cellular activity of N370S beta -glucosidase: a therapeutic strategy for Gaucher disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017985

12 September 2017

Gaucher disease: Perspectives on a prototype lysosomal disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017985

12 September 2017

Polyhydroxylated bicyclic isoureas and guanidines are potent glucocerebrosidase inhibitors and nanomolar enzyme activity enhancers in Gaucher cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017985

14 September 2017

Alpha-1-C-octyl-1-deoxynojirimycin as a pharmacological chaperone for Gaucher disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017985

14 September 2017

Click chemistry approach to new N-substituted aminocyclitols as potential pharmacological chaperones for Gaucher disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017985

21 August 2018

Regio- and stereoselective synthesis of aminoinositols and 1,2-diaminoinositols from conduritol B epoxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017985

21 August 2018

Synthesis of 1,2-diamino-1,2-dideoxy-myo- inositol-derived ligands for the investigation of metal complex reactivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017985

21 August 2018

Aminocyclitols as pharmacological chaperones for glucocerebrosidase, a defective enzyme in Gaucher disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24900357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the ERAD process of the L444P mutant glucocerebrosidase variant

1 reference

https://pubmed.ncbi.nlm.nih.gov/24900357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical modification of beta-glucocerebrosidase inhibitor N-octyl-beta-valienamine: synthesis and biological evaluation of N-alkanoyl and N-alkyl derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/24900357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of specific deoxynojirimycin-type inhibitors of the non-lysosomal glucosylceramidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/24900357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design and synthesis of highly potent and selective pharmacological chaperones for the treatment of Gaucher's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24900357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rational design and synthesis of highly potent beta-glucocerebrosidase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/24900357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Practical synthesis of (-)-1-amino-1-deoxy-myo-inositol from achiral precursors

1 reference

https://pubmed.ncbi.nlm.nih.gov/24900357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/ML200098J

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900357%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900357%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900357%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

ResearchGate publication ID

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