(Q39519115)

12 September 2017

title

Dichloroacetate induces apoptosis of epithelial ovarian cancer cells through a mechanism involving modulation of oxidative stress (English)

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12 September 2017

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5

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12 September 2017

Ghassan M Saed

1

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12 September 2017

Nicole M Fletcher

series ordinal

2

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12 September 2017

Zhong L Jiang

series ordinal

3

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12 September 2017

Husam M Abu-Soud

series ordinal

4

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12 September 2017

publication date

23 June 2011

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12 September 2017

number of pages

9

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based on heuristic

inferred from page(s)

published in

Reproductive Sciences

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12 September 2017

volume

18

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12 September 2017

issue

12

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12 September 2017

page(s)

1253-1261

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Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer

12 September 2017

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Tumor microenvironment: the role of the tumor stroma in cancer

21 January 2018

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Myeloperoxidase serves as a redox switch that regulates apoptosis in epithelial ovarian cancer.

21 January 2018

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Metabolic disorder, inflammation, and deregulated molecular pathways converging in pancreatic cancer development: implications for new therapeutic strategies

21 January 2018

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Oxidative stress and apoptosis: impact on cancer therapy.

21 January 2018

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Interfering with ROS Metabolism in Cancer Cells: The Potential Role of Quercetin.

21 January 2018

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ROS stress in cancer cells and therapeutic implications

21 January 2018

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Oxidative stress, inflammation, and cancer: how are they linked?

21 January 2018

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Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression

21 January 2018

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Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer

21 January 2018

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Tumor cell metabolism: cancer's Achilles' heel

21 January 2018

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Therapeutic strategies by modulating oxygen stress in cancer and inflammation

21 January 2018

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Regulation of cellular signals from nutritional molecules: a specific role for phytochemicals, beyond antioxidant activity

21 January 2018

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Distinct structural mechanisms for inhibition of pyruvate dehydrogenase kinase isoforms by AZD7545, dichloroacetate, and radicicol

21 January 2018

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Regulation of matrix metalloproteinase-1 and tissue inhibitor of matrix metalloproteinase-1 by dichloroacetic acid in human fibroblasts from normal peritoneum and adhesions

21 January 2018

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Modulation of the expression of tissue plasminogen activator and its inhibitor by hypoxia in human peritoneal and adhesion fibroblasts

21 January 2018

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Cell transformation by the superoxide-generating oxidase Mox1

21 January 2018

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Why do cancers have high aerobic glycolysis?

21 January 2018

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Identification of renox, an NAD(P)H oxidase in kidney

21 January 2018

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Role for mitochondrial oxidants as regulators of cellular metabolism

21 January 2018

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Sublethal mitochondrial stress with an attendant stoichiometric augmentation of reactive oxygen species may precipitate many of the beneficial alterations in cellular physiology produced by caloric restriction, intermittent fasting, exercise and die

21 January 2018

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Regulation of cancer cell metabolism

21 January 2018

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Superoxide dismutases in malignant cells and human tumors

21 January 2018

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Intrinsic oxidative stress in cancer cells: a biochemical basis for therapeutic selectivity

21 January 2018

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Membrane oxidative damage and apoptosis in cervical carcinoma cells of patients after radiation therapy

21 January 2018

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Reactive oxygen species in tumor progression

21 January 2018

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Dietary antioxidants, supplements, and risk of epithelial ovarian cancer

21 January 2018

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A prospective cohort study on intake of retinol, vitamins C and E, and carotenoids and prostate cancer risk (Netherlands).

21 January 2018

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HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

21 January 2018

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Controlled clinical trial of dichloroacetate for treatment of congenital lactic acidosis in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719111411731

Evaluation of long-term treatment of children with congenital lactic acidosis with dichloroacetate

21 January 2018

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Therapeutic potential of dichloroacetate for pyruvate dehydrogenase complex deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719111411731

Reversal of the glycolytic phenotype by dichloroacetate inhibits metastatic breast cancer cell growth in vitro and in vivo

21 January 2018

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A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth

21 January 2018

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Mitaplatin, a potent fusion of cisplatin and the orphan drug dichloroacetate

21 January 2018

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Cell metabolism in the regulation of programmed cell death

21 January 2018

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Multifaceted roles of glycolytic enzymes.

21 January 2018

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Cancer's molecular sweet tooth and the Warburg effect.

21 January 2018

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The pharmacology of dichloroacetate

21 January 2018

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https://api.crossref.org/works/10.1177%2F1933719111411731

Recent advances in mechanisms regulating glucose oxidation at the level of the pyruvate dehydrogenase complex by PDKs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719111411731

Iron intake, oxidative stress-related genes (MnSOD and MPO) and prostate cancer risk in CARET cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719111411731

21 January 2018

Inflammation and cancer

1 reference

https://api.crossref.org/works/10.1177%2F1933719111411731

Oxidants, oxidative stress and the biology of ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719111411731

Myeloperoxidase up-regulates the catalytic activity of inducible nitric oxide synthase by preventing nitric oxide feedback inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719111411731

Superoxide dismutase as a target for the selective killing of cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1933719111411731

21 January 2018

Identifiers

DOI

10.1177/1933719111411731

1 reference

12 September 2017

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