(Q39524591)

12 September 2017

The development of tamoxifen for breast cancer therapy: a tribute to the late Arthur L. Walpole (English)

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12 September 2017

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1

V C Jordan

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PubMed ID

3048447

12 September 2017

language of work or name

English

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publication date

1 July 1988

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Breast Cancer Research and Treatment

12 September 2017

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12 September 2017

11

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12 September 2017

197-209

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12 September 2017

3

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https://scigraph.springernature.com/pub.10.1007/bf01807278

12 September 2017

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cites work

Oestradiol Receptors in Carcinoma and Benign Disease of the Breast: An In Vitro Assay

1 reference

https://api.crossref.org/works/10.1007%2FBF01807278

Bladder Tumours Induced in Rats of Two Strains with 3:2′-Dimethyl-4-Aminodiphenyl

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01807278

Triaethyleneimino-s-triazine in human malignant disease: a preliminary trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01807278

A New Anti-oestrogenic Agent in Late Breast Cancer: An Early Clinical Appraisal of ICI46474

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01807278

Tamoxifen (ICI 46,474) and the human carcinoma 8S oestrogen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01807278

Evidence for the metabolic activation of non-steroidal antioestrogens: a study of structure-activity relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01807278

Optimised analysis of tamoxifen and its main metabolites in the plasma and cytosol of mammary tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01807278

The binding of estradiol-17beta to human breast cancers and other tissues in vitro

21 January 2018

1 reference

12 December 2020

Adjuvant chemotherapy with and without tamoxifen in the treatment of primary breast cancer: 5-year results from the National Surgical Adjuvant Breast and Bowel Project Trial

1 reference

12 December 2020

Tamoxifen therapy in premenopausal women with metastatic breast cancer

1 reference

12 December 2020

Adjuvant tamoxifen in the management of operable breast cancer: the Scottish Trial. Report from the Breast Cancer Trials Committee, Scottish Cancer Trials Office (MRC), Edinburgh

1 reference

12 December 2020

The Christie Hospital tamoxifen (Nolvadex) adjuvant trial for operable breast carcinoma--7-yr results

1 reference

12 December 2020

Chemohormonal therapy and endocrine function in breast cancer patients

1 reference

12 December 2020

Response to oophorectomy after tamoxifen failure in a premenopausal patient

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12 December 2020

Tamoxifen aziridines: effective inactivators of the estrogen receptor

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12 December 2020

Tamoxifen as an anti-tumour agent: oestrogen binding as a predictive test for tumour response

1 reference

12 December 2020

Endocrine profiles in tamoxifen-induced ovulatory cycles

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12 December 2020

Serum lipoproteins and proteins after breast cancer surgery and effects of tamoxifen

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12 December 2020

Steroidal pure antioestrogens

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12 December 2020

Long-term adjuvant tamoxifen study: clinical update

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12 December 2020

Long-term tamoxifen adjuvant therapy in node-positive breast cancer: a metabolic and pilot clinical study

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12 December 2020

Combination Chemotherapy as an Adjuvant Treatment in Operable Breast Cancer

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12 December 2020

The metabolism of tamoxifen in human

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12 December 2020

1-Phenylalanine mustard (L-PAM) in the management of primary breast cancer. A report of early findings

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12 December 2020

The in vitro uptake of oestradiol in biopsies from 25 breast cancer patients

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12 December 2020

The Walker carcinoma 256 in the screening of tumour inhibitors

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12 December 2020

Adjuvant tamoxifen therapy for early breast cancer: an experimental study with reference to oestrogen and progesterone receptors

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12 December 2020

Cytotoxic agents: II. Bis-epoxides and related compounds

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12 December 2020

Measurement of tamoxifen in serum by thin-layer densitometry

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12 December 2020

Specific estrogen binding by the cytoplasm fof human breast carcinoma.

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12 December 2020

Role of hexamethylmelamine in the treatment of ovarian cancer: where is the needle in the haystack?

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12 December 2020

Influence of tumor estrogen and progesterone receptor levels on the response to tamoxifen and chemotherapy in primary breast cancer

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12 December 2020

High-performance liquid chromatographic analysis of tamoxifen and major metabolites in human plasma

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12 December 2020

Cytotoxic agents. IV. The carcinogenic actions of some monofunctional ethyleneimine derivatives

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12 December 2020

Randomised trial of chemo-endocrine therapy, endocrine therapy, and mastectomy alone in postmenopausal patients with operable breast cancer and axillary node metastasis

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12 December 2020

Long-term adjuvant therapy with tamoxifen: effects on sex hormone binding globulin and antithrombin III

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12 December 2020

Adjuvant tamoxifen treatment of elderly women with stage II breast cancer. A double-blind comparison with placebo

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12 December 2020

Postcoital contraception

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12 December 2020

A new derivative of triphenylethylene: effect on implantation and mode of action in rats.

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12 December 2020

Contrasting Endocrine Activities of cis and trans Isomers in a Series of Substituted Triphenylethylenes

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12 December 2020

Potent agonist and antagonist analogues of luliberin containing an azaglycine residue in position 10

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12 December 2020

Effect of the anti-oestrogen tamoxifen on plasma levels of luteinizing hormone, follicle-stimulating hormone, prolactin, oestradiol and progesterone in normal pre-menopausal women

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12 December 2020

The pharmacology and clinical uses of tamoxifen

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12 December 2020

Triethylene melamine in the treatment of neoplastic disease; a compound with nitrogen-mustardlike activity suitable for oral and intravenous use

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12 December 2020

Estrogen receptor in a human cell line (MCF-7) from breast carcinoma

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12 December 2020

Evaluation of the antitumour activity of the non-steroidal antioestrogen monohydroxytamoxifen in the DMBA-induced rat mammary carcinoma model

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12 December 2020

Species-specific pharmacology of antiestrogens: role of metabolism

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12 December 2020

Estradiol-stimulated growth of MCF-7 tumors implanted in athymic mice: a model to study the tumoristatic action of tamoxifen

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12 December 2020

A randomized comparison of tamoxifen with surgical oophorectomy in premenopausal patients with advanced breast cancer

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12 December 2020

Antitumor actions of keoxifene and tamoxifen in the N-nitrosomethylurea-induced rat mammary carcinoma model

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12 December 2020

Bone mineral density in women with breast cancer treated with adjuvant tamoxifen for at least two years

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12 December 2020

Tamoxifen treatment of metastatic breast cancer and antithrombin III levels

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12 December 2020

Paired-ion chromatographic analysis of tamoxifen and two major metabolites in plasma

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12 December 2020

Use of analogues of luteinizing hormone-releasing hormone for the treatment of cancer

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12 December 2020

I.C.I. 46,474 in breast cancer

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12 December 2020

CLOMIPHENE CITRATE (NSC-35770) IN DISSEMINATED MAMMARY CARCINOMA

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12 December 2020

Effects of anti-estrogens on bone in castrated and intact female rats

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12 December 2020

Controlled trial of tamoxifen as single adjuvant agent in management of early breast cancer. Analysis at six years by Nolvadex Adjuvant Trial Organisation

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12 December 2020

Efficient and highly selective covalent labeling of the estrogen receptor with [3H]tamoxifen aziridine

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12 December 2020

The induction of ovulation by tamoxifen

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12 December 2020

A comparsion of the effects of clomiphene and tamoxifen treatment on the concentrations of oestradiol and progesterone in the peripheral plasma of infertile women

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12 December 2020

Identification and biological activity of tamoxifen metabolites in human serum

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12 December 2020

Treatment of primary breast cancer with chemotherapy and tamoxifen

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12 December 2020

Cytotoxic agents: III, derivatives of ethyleneimine

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12 December 2020

Mode of action of I.C.I. 46,474 in preventing implantation in rats

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12 December 2020

Endocrine status of premenopausal node-positive breast cancer patients following adjuvant chemotherapy and long-term tamoxifen

1 reference

12 December 2020

Determination and pharmacology of a new hydroxylated metabolite of tamoxifen observed in patient sera during therapy for advanced breast cancer.

1 reference

12 December 2020

Anti-oestrogen Therapy for Breast Cancer: A Trial of Tamoxifen at Two Dose Levels

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12 December 2020

A non-steroidal estrogen antiagonist 1-(p-2-diethylaminoethoxyphenyl)-1-phenyl-2-p-methoxyphenyl ethanol

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12 December 2020

"Role of hexamethylmelamine in the treatment of ovarian cancer: where is the needle in the haystack?"

1 reference

12 December 2020

The effect of synthetic anti-oestrogens on the growth and biochemistry of rat mammary tumours

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12 December 2020

Endocrine effects of adjuvant chemotherapy and long-term tamoxifen administration on node-positive patients with breast cancer

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12 December 2020

The agonistic-antagonistic properties of clomiphene: a review

1 reference

12 December 2020

Effect of some triphenylethylenes on oestradiol binding in vitro to macromolecules from uterus and anterior pituitary.

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12 December 2020

Reversal of the antitumor effects of tamoxifen by progesterone in the 7,12-dimethylbenzanthracene-induced rat mammary carcinoma model

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12 December 2020

Hydroxylated metabolites of tamoxifen are formed in vivo and bound to estrogen receptor in target tissues.

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12 December 2020

Clinical analysis of tamoxifen, an anti-neoplastic agent, in plasma

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12 December 2020

New biospecific adsorbents for the purification of estradiol receptor

1 reference

12 December 2020

Adjuvant tamoxifen for operable carcinoma of the breast: report of clinical trial by the Christie Hospital and Holt Radium Institute

1 reference

12 December 2020

Influence of Synthetic Oestrogens on Advanced Malignant Disease

1 reference

12 December 2020

Zoladex: a sustained-release, monthly luteinizing hormone-releasing hormone analogue for the treatment of advanced prostate cancer

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12 December 2020

Hexamethylmelamine in alkylating agent-resistant ovarian carcinoma

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12 December 2020

The nitrogen mustard-like actions of 2,4,6-tris (ethylenimino)-s-triazine and other bis(ethylenimines)

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12 December 2020

N-demethylation of the antineoplastic agent hexamethylmelamine by rats and man

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12 December 2020

Oestrogen-responsive human breast cancer in long term tissue culture

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12 December 2020

Tamoxifen prevents the skeletal effects of ovarian hormone deficiency in rats

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12 December 2020

Controlled trial of tamoxifen as adjuvant agent in management of early breast cancer. Interim analysis at four years by Nolvadex Adjuvant Trial Organisation

1 reference

12 December 2020

A monohydroxylated metabolite of tamoxifen with potent antioestrogenic activity

1 reference

12 December 2020

Randomized trial of bilateral oophorectomy versus tamoxifen in premenopausal women with metastatic breast cancer

1 reference

12 December 2020

Determination of tamoxifen and an hydroxylated metabolite in plasma from patients with advanced breast cancer using gas chromatography-mass spectrometry

1 reference

12 December 2020

Beneficial effect of adjuvant tamoxifen therapy in primary breast cancer patients with high oestrogen receptor values

1 reference

12 December 2020

Systemic adjuvant therapy in treatment of primary operable breast cancer: National Surgical Adjuvant Breast and Bowel Project experience

1 reference

12 December 2020

Antihormone treatment of stage IV breast cancer

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12 December 2020

New cytotoxic agents with tumour-inhibitory activity.

1 reference

12 December 2020

Tamoxifen therapy in premenopausal patients with metastatic breast cancer

1 reference

12 December 2020

Endocrine Consequences of Continuous Antiestrogen Therapy with Tamoxifen in Premenopausal Women

1 reference

12 December 2020

Effects of tamoxifen on human breast cancer cell cycle kinetics: accumulation of cells in early G1 phase

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12 December 2020

Synthetic oestrogens in mammary cancer

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12 December 2020

New synthetic agent for the induction of ovulation: preliminary trials in women

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12 December 2020

Effect of estrogens and antiestrogens on growth of human breast cancer cells in athymic nude mice

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12 December 2020

Human breast cancer in the athymic nude mouse: cytostatic effects of long-term antiestrogen therapy

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12 December 2020

Treatment of advanced prostatic cancer with LHRH analogue ICI 118630: clinical response and hormonal mechanisms

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12 December 2020

Effects of oestradiol - 17beta and tamoxifen on total and accessible cytoplasmic oestradiol - 17beta receptors in DMBA-induced rat mammary tumours

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12 December 2020

Observations on the use of a non-steroidal estrogen antagonist: MER-25

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12 December 2020

Pharmacology of tamoxifen in laboratory animals.

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12 December 2020

Aromatic amines as carcinogens in industry

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12 December 2020

Effects of adjuvant chemohormonal therapy on the ovarian and adrenal function of breast cancer patients

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12 December 2020

Treatment of menometrorrhagia with an anti-oestrogen

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12 December 2020

Plasma levels and urinary excretion of hexamethylmelamine following oral administration to human subjects with cancer

1 reference

12 December 2020

Prolonging tamoxifen therapy for primary breast cancer. Findings from the National Surgical Adjuvant Breast and Bowel Project clinical trial

1 reference

12 December 2020

Tamoxifen induces accumulation of MCF 7 human mammary carcinoma cells in the G0/G1 phase of the cell cycle

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12 December 2020

Effect of tamoxifen (ICI 46,474) on initiation and growth of DMBA-induced rat mammary carcinomata

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12 December 2020

Structural derivatives of tamoxifen and oestradiol 3-methyl ether as potential alkylating antioestrogens

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12 December 2020

Tamoxifen as an anti-tumour agent: effect on oestrogen binding

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12 December 2020

Adjuvant tamoxifen in postmenopausal breast cancer: preliminary results of a randomized trial

1 reference

12 December 2020

Tamoxifen as an anti-tumour agent: role of oestradiol and prolactin

1 reference

12 December 2020

Therapeutic significance and the mechanism of action of the LH-RH agonist ICI 118630 in breast and prostate cancer

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12 December 2020

Role and mechanism of action of tamoxifen in premenopausal women with metastatic breast carcinoma

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12 December 2020

The metabolism of tamoxifen (I.C.I. 46,474). I. In laboratory animals.

1 reference

12 December 2020

Determination of tamoxifen and metabolites in human serum by high-performance liquid chromatography with post-column fluorescence activation

1 reference

12 December 2020

Inhibition of the Crocker mouse sarcoma 180 by certain ethyleneimine derivatives and related compounds

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12 December 2020

Cytotoxic agents: 1, methylolamides with tumour inhibitory activity, and related inactive compounds

1 reference

12 December 2020

An estrogen receptor model to describe the regulation of prolactin synthesis by antiestrogens in vitro

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12 December 2020

Identifiers

DOI

10.1007/BF01807278

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12 September 2017

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PubMed ID

3048447