(Q39524782)

12 September 2017

title

Type II ligands as chemical auxiliaries to favor enzymatic transformations by P450 2E1. (English)

1 reference

12 September 2017

Amélie Ménard

1

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12 September 2017

Camilo Fabra

series ordinal

2

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12 September 2017

Yue Huang

series ordinal

3

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12 September 2017

Karine Auclair

series ordinal

4

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12 September 2017

publication date

5 November 2012

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12 September 2017

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12 September 2017

volume

13

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12 September 2017

issue

17

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12 September 2017

page(s)

2527-2536

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Extending the capabilities of nature's most versatile catalysts: directed evolution of mammalian xenobiotic-metabolizing P450s.

12 September 2017

cites work

1 reference

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Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation

21 January 2018

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Replacement of natural cofactors by selected hydrogen peroxide donors or organic peroxides results in improved activity for CYP3A4 and CYP2D6.

21 January 2018

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CYP3A4 activity in the presence of organic cosolvents, ionic liquids, or water-immiscible organic solvents

21 January 2018

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Site-specific fluorescent labeling and oriented immobilization of a triple mutant of CYP3A4 via C64

21 January 2018

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The effects of type II binding on metabolic stability and binding affinity in cytochrome P450 CYP3A4.

21 January 2018

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Cytochrome P450 2C9 type II binding studies on quinoline-4-carboxamide analogues

21 January 2018

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Modeling and synthesis of novel tight-binding inhibitors of cytochrome P450 2C9.

21 January 2018

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The effects of nitrogen-heme-iron coordination on substrate affinities for cytochrome P450 2E1

21 January 2018

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Sterol biosynthesis inhibitors: Their current status and modes of action

21 January 2018

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CYP17 inhibitors for prostate cancer therapy

21 January 2018

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P450 interaction with HIV protease inhibitors: relationship between metabolic stability, inhibitory potency, and P450 binding spectra

21 January 2018

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Inhibition of cytochromes P450 by antifungal imidazole derivatives

21 January 2018

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Triazole antifungal agents drug-drug interactions involving hepatic cytochrome P450.

21 January 2018

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Drug-drug interactions by azole antifungals: Beyond a dogma of CYP3A4 enzyme activity inhibition

21 January 2018

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Drug interactions with cimetidine: an update

21 January 2018

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Discovery of potent and novel S-nitrosoglutathione reductase inhibitors devoid of cytochrome P450 activities.

21 January 2018

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Surface plasmon resonance analysis of antifungal azoles binding to CYP3A4 with kinetic resolution of multiple binding orientations

21 January 2018

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Stereochemical aspects of itraconazole metabolism in vitro and in vivo

21 January 2018

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Comparative study of the affinity and metabolism of type I and type II binding quinoline carboxamide analogues by cytochrome P450 3A4

21 January 2018

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1,2,3-Triazole-heme interactions in cytochrome P450: functionally competent triazole-water-heme complexes.

21 January 2018

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Efficient bioelectronic actuation of the natural catalytic pathway of human metabolic cytochrome P450s.

21 January 2018

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P450 interaction with farnesyl-protein transferase inhibitors metabolic stability, inhibitory potency, and P450 binding spectra in human liver microsomes

21 January 2018

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Characterization of type II ligands in CYP2C9 and CYP3A4.

21 January 2018

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Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates

21 January 2018

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Heme-iron oxygenases: powerful industrial biocatalysts?

21 January 2018

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Integrating medicinal chemistry, organic/combinatorial chemistry, and computational chemistry for the discovery of selective estrogen receptor modulators with Forecaster, a novel platform for drug discovery.

21 January 2018

1 reference

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Human Cytochrome P450 2E1 Structures with Fatty Acid Analogs Reveal a Previously Unobserved Binding Mode

21 January 2018

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Site of metabolism prediction on cytochrome P450 2C9: a knowledge-based docking approach.

21 January 2018

1 reference

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Ensemble modeling of substrate binding to cytochromes P450: analysis of catalytic differences between CYP1A orthologs.

21 January 2018

1 reference

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Expression of modified human cytochrome P450 2E1 in Escherichia coli, purification, and spectral and catalytic properties.

21 January 2018

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Cytochromes P450 as useful biocatalysts: addressing the limitations

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1002/CBIC.201200524

1 reference

release_vocd3xrjzrftnbux564kaxwumq

12 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/vocd3xrjzrftnbux564kaxwumq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference