(Q39529070)

12 September 2017

title

TNF-dependent signaling pathways in liver cancer: promising targets for therapeutic strategies?. (English)

1 reference

12 September 2017

0 references

1 reference

Christoph Roderburg

1

1 reference

12 September 2017

Jeremie Gautheron

series ordinal

2

1 reference

12 September 2017

Tom Luedde

series ordinal

3

1 reference

12 September 2017

publication date

24 October 2012

1 reference

12 September 2017

1 reference

12 September 2017

volume

30

1 reference

12 September 2017

issue

5

1 reference

12 September 2017

page(s)

500-507

1 reference

12 September 2017

cites work

Cancer statistics, 2009

1 reference

Hepatocellular carcinoma: epidemiology, surveillance, and diagnosis

21 January 2018

1 reference

Hepatocellular carcinoma in non-alcoholic steatohepatitis: Growing evidence of an epidemic?

21 January 2018

1 reference

The etiology of hepatocellular carcinoma and consequences for treatment

21 January 2018

1 reference

Hepatocellular carcinoma: epidemiology, risk factors, and screening

21 January 2018

1 reference

Hepatocellular cancer: optimal strategies for screening and surveillance

21 January 2018

1 reference

Molecularly targeted therapy in hepatocellular carcinoma.

21 January 2018

1 reference

Predicting survival after liver transplantation in patients with hepatocellular carcinoma beyond the Milan criteria: a retrospective, exploratory analysis

21 January 2018

1 reference

21 January 2018

Hepatocellular carcinoma

1 reference

Review article: hepatocellular carcinoma: indications for liver transplantation

21 January 2018

1 reference

Sorafenib in advanced hepatocellular carcinoma

21 January 2018

1 reference

Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial

21 January 2018

1 reference

Hepatitis B virus DNA levels and outcomes in chronic hepatitis B.

21 January 2018

1 reference

Incidence of hepatocellular carcinoma and associated risk factors in hepatitis C-related advanced liver disease

21 January 2018

1 reference

Current strategy for staging and treatment: the BCLC update and future prospects.

21 January 2018

1 reference

Role of TNF superfamily ligands in innate immunity

21 January 2018

1 reference

An endotoxin-induced serum factor that causes necrosis of tumors

21 January 2018

1 reference

Phase I study of recombinant human tumor necrosis factor

21 January 2018

1 reference

A phase I trial of intravenously-administered recombinant tumor necrosis factor-alpha in cancer patients

21 January 2018

1 reference

TNF-alpha in cancer treatment: molecular insights, antitumor effects, and clinical utility

21 January 2018

1 reference

Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat.

21 January 2018

1 reference

Induction of tumor necrosis factor alpha production by human hepatocytes in chronic viral hepatitis

21 January 2018

1 reference

Virus-triggered acquired immunodeficiency by cytotoxic T-cell-dependent destruction of antigen-presenting cells and lymph follicle structure

21 January 2018

1 reference

Tumor necrosis factor-alpha 308.2 polymorphism is associated with advanced hepatic fibrosis and higher risk for hepatocellular carcinoma

21 January 2018

1 reference

Gene expression in fixed tissues and outcome in hepatocellular carcinoma.

21 January 2018

1 reference

Mechanisms of Liver Injury. I. TNF-alpha-induced liver injury: role of IKK, JNK, and ROS pathways

21 January 2018

1 reference

TNFR signaling: ubiquitin-conjugated TRAFfic signals control stop-and-go for MAPK signaling complexes

21 January 2018

1 reference

Ubiquitin-mediated activation of TAK1 and IKK.

21 January 2018

1 reference

The IkappaB kinase - a bridge between inflammation and cancer

21 January 2018

1 reference

Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor

21 January 2018

1 reference

Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune re

21 January 2018

1 reference

Signal transduction by tumor necrosis factor and its relatives

21 January 2018

1 reference

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

21 January 2018

1 reference

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

21 January 2018

1 reference

Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality

21 January 2018

1 reference

IKK1-deficient mice exhibit abnormal development of skin and skeleton

21 January 2018

1 reference

JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development.

21 January 2018

1 reference

Disruption of JNK2 decreases the cytokine response to Plasmodium falciparum glycosylphosphatidylinositol in vitro and confers protection in a cerebral malaria model

21 January 2018

1 reference

JNK1 Is Required for Maintenance of Neuronal Microtubules and Controls Phosphorylation of Microtubule-Associated Proteins

21 January 2018

1 reference

Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2.

21 January 2018

1 reference

The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development.

21 January 2018

1 reference

Deficiency of the stress kinase p38alpha results in embryonic lethality: characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells

21 January 2018

1 reference

Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis

21 January 2018

1 reference

NF-κB in the liver--linking injury, fibrosis and hepatocellular carcinoma

21 January 2018

1 reference

Intracellular survival pathways in the liver

21 January 2018

1 reference

Evaluation of the role of nuclear factor-kappaB signaling in liver injury using genetic animal models

21 January 2018

1 reference

NF-kappaB functions as a tumour promoter in inflammation-associated cancer

21 January 2018

1 reference

A lymphotoxin-driven pathway to hepatocellular carcinoma

21 January 2018

1 reference

IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis

21 January 2018

1 reference

Hepatic NF-kappa B essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis

21 January 2018

1 reference

Hepatocyte-specific IKK gamma/NEMO expression determines the degree of liver injury

21 January 2018

1 reference

Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation

21 January 2018

1 reference

Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases

21 January 2018

1 reference

p38 alpha MAPK inhibits JNK activation and collaborates with IkappaB kinase 2 to prevent endotoxin-induced liver failure

21 January 2018

1 reference

TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer.

21 January 2018

1 reference

c-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration

21 January 2018

1 reference

Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

21 January 2018

1 reference

Defective T Cell Differentiation in the Absence of Jnk1

21 January 2018

1 reference

p38α suppresses normal and cancer cell proliferation by antagonizing the JNK–c-Jun pathway

21 January 2018

1 reference

Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular Carcinoma

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1159/000341700

1 reference

12 September 2017

1 reference