(Q39557102)

English

An anti-Aβ (amyloid β) single-chain variable fragment prevents amyloid fibril formation and cytotoxicity by withdrawing Aβ oligomers from the amyloid pathway

scientific article published on July 2011

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Europe PubMed Central

PubMed publication ID

13 September 2017

An anti-Aβ (amyloid β) single-chain variable fragment prevents amyloid fibril formation and cytotoxicity by withdrawing Aβ oligomers from the amyloid pathway (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

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Sandra Villegas

4

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

author name string

Marta Marín-Argany

1

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Geovanny Rivera-Hernández

2

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Joaquim Martí

3

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Europe PubMed Central

PubMed publication ID

13 September 2017

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publication date

1 July 2011

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Europe PubMed Central

PubMed publication ID

13 September 2017

Biochemical Journal

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Europe PubMed Central

PubMed publication ID

13 September 2017

437

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Europe PubMed Central

PubMed publication ID

13 September 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

25-34

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

1 reference

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A century-old debate on protein aggregation and neurodegeneration enters the clinic

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Accelerated plaque accumulation, associative learning deficits, and up-regulation of alpha 7 nicotinic receptor protein in transgenic mice co-expressing mutant human presenilin 1 and amyloid precursor proteins

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Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

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Immunotherapeutic strategies for Alzheimer's disease treatment.

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Disaggregation of Alzheimer beta-amyloid by site-directed mAb.

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Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

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Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

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21 January 2018

Amyloid-beta immunotherapy for Alzheimer's disease: the end of the beginning

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Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.

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Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease

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Amyloid-beta immunisation for Alzheimer's disease

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Targeting beta-amyloid pathology in Alzheimer's disease with Abeta immunotherapy

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Cerebral hemorrhage after passive anti-Abeta immunotherapy

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Amelioration of amyloid load by anti-Abeta single-chain antibody in Alzheimer mouse model

1 reference

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21 January 2018

Anti-oligomeric Abeta single-chain variable domain antibody blocks Abeta-induced toxicity against human neuroblastoma cells

1 reference

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Engineered antibody intervention strategies for Alzheimer's disease and related dementias by targeting amyloid and toxic oligomers.

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Production of a functional catalytic antibody ScFv-NusA fusion protein in bacterial cytoplasm

1 reference

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Thioredoxin fusions increase folding of single chain Fv antibodies in the cytoplasm of Escherichia coli: evidence that chaperone activity is the prime effect of thioredoxin

1 reference

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Efficient site-specific processing of fusion proteins by tobacco vein mottling virus protease in vivo and in vitro

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A generic protocol for the expression and purification of recombinant proteins in Escherichia coli using a combinatorial His6-maltose binding protein fusion tag.

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Calculation of protein extinction coefficients from amino acid sequence data

1 reference

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Structure and dynamics of membrane proteins as studied by infrared spectroscopy

1 reference

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21 January 2018

Applications of thermolysin in protein structural analysis

1 reference

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21 January 2018

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

1 reference

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21 January 2018

De novo designed peptide-based amyloid fibrils

1 reference

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21 January 2018

A simple vector system to improve performance and utilisation of recombinant antibodies

1 reference

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21 January 2018

Critical structural and functional roles for the N-terminal insertion sequence in surfactant protein B analogs.

1 reference

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21 January 2018

A common beta-sheet architecture underlies in vitro and in vivo beta2-microglobulin amyloid fibrils

1 reference

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21 January 2018

FTIR reveals structural differences between native beta-sheet proteins and amyloid fibrils.

1 reference

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21 January 2018

Competing pathways determine fibril morphology in the self-assembly of beta2-microglobulin into amyloid.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101712

21 January 2018

Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T1.

1 reference

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21 January 2018

An electrospray ionization mass spectrometry investigation of 1-anilino-8-naphthalene-sulfonate (ANS) binding to proteins

1 reference

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21 January 2018

Partially unfolded states of beta(2)-microglobulin and amyloid formation in vitro

1 reference

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21 January 2018

Folding of a large ribozyme during transcription and the effect of the elongation factor NusA.

1 reference

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21 January 2018

Antiferritin single-chain Fv fragment is a functional protein with properties of a partially structured state: comparison with the completely folded V(L) domain.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101712

21 January 2018

Four-state equilibrium unfolding of an scFv antibody fragment.

1 reference

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21 January 2018

How additives influence the refolding of immunoglobulin-folded proteins in a stepwise dialysis system. Spectroscopic evidence for highly efficient refolding of a single-chain Fv fragment

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101712

21 January 2018

Trimolecular complex formation of IgE, Fc epsilon RI, and a recombinant nonanaphylactic single-chain antibody fragment with high affinity for IgE.

1 reference

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21 January 2018

Altered Dimer Interface Decreases Stability in an Amyloidogenic Protein

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101712

21 January 2018

Influence of aggregation propensity and stability on amyloid fibril formation as studied by Fourier transform infrared spectroscopy and two-dimensional COS analysis

1 reference

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21 January 2018

Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models.

1 reference

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21 January 2018

The hierarchy of mutations influencing the folding of antibody domains in Escherichia coli

1 reference

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21 January 2018

Mutual Stabilization of VLand VHin Single-Chain Antibody Fragments, Investigated with Mutants Engineered for Stability†

1 reference

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21 January 2018

Factors Influencing the Dimer to Monomer Transition of an Antibody Single-Chain Fv Fragment†

1 reference

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21 January 2018

Different Equilibrium Stability Behavior of ScFv Fragments: Identification, Classification, and Improvement by Protein Engineering†

1 reference

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21 January 2018

Termination of transcription by nusA gene protein of Escherichia coli

1 reference

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21 January 2018

Identifiers

10.1042/BJ20101712

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

release_ivgjepyi7fgsfcotwxihg55d2q

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

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