(Q39557334)

English

Examination of Org 26576, an AMPA receptor positive allosteric modulator, in patients diagnosed with major depressive disorder: an exploratory, randomized, double-blind, placebo-controlled trial

scientific article published on 6 September 2012

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scholarly article

1 reference

Europe PubMed Central

13 September 2017

Examination of Org 26576, an AMPA receptor positive allosteric modulator, in patients diagnosed with major depressive disorder: an exploratory, randomized, double-blind, placebo-controlled trial (English)

1 reference

Europe PubMed Central

13 September 2017

0 references

major depressive disorder

1 reference

based on heuristic

inferred from title

author name string

Kari R Nations

1

1 reference

Europe PubMed Central

13 September 2017

Peter Dogterom

2

1 reference

Europe PubMed Central

13 September 2017

Roberta Bursi

3

1 reference

Europe PubMed Central

13 September 2017

Jacques Schipper

4

1 reference

Europe PubMed Central

13 September 2017

Scott Greenwald

5

1 reference

Europe PubMed Central

13 September 2017

David Zraket

6

1 reference

Europe PubMed Central

13 September 2017

Lev Gertsik

7

1 reference

Europe PubMed Central

13 September 2017

Jack Johnstone

8

1 reference

Europe PubMed Central

13 September 2017

Allen Lee

9

1 reference

Europe PubMed Central

13 September 2017

Yogesh Pande

10

1 reference

Europe PubMed Central

13 September 2017

Ge Ruigt

11

1 reference

Europe PubMed Central

13 September 2017

Larry Ereshefsky

12

1 reference

Europe PubMed Central

13 September 2017

language of work or name

0 references

publication date

6 September 2012

1 reference

Europe PubMed Central

13 September 2017

Journal of Psychopharmacology

1 reference

Europe PubMed Central

13 September 2017

26

1 reference

Europe PubMed Central

13 September 2017

12

1 reference

Europe PubMed Central

13 September 2017

1525-1539

1 reference

Europe PubMed Central

13 September 2017

Role of excitatory amino acids in the control of growth hormone secretion

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Effects of two selective serotonin reuptake inhibitor antidepressants, sertraline and escitalopram, on aldosterone/renin ratio in normotensive depressed male patients.

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21 January 2018

A role for AMPA receptors in mood disorders

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Pharmacology of ampakine modulators: from AMPA receptors to synapses and behavior

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Frontal midline theta rhythms reflect alternative activation of prefrontal cortex and anterior cingulate cortex in humans.

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21 January 2018

Cognitive deficits in depression: possible implications for functional neuropathology

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21 January 2018

Chronic AMPA receptor potentiator (LY451646) treatment increases cell proliferation in adult rat hippocampus

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21 January 2018

Early reduction in prefrontal theta QEEG cordance value predicts response to venlafaxine treatment in patients with resistant depressive disorder

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The change of prefrontal QEEG theta cordance as a predictor of response to bupropion treatment in patients who had failed to respond to previous antidepressant treatments

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Endophenotypes for psychiatric disorders: ready for primetime?

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Antidepressant effects of ketamine in depressed patients

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21 January 2018

Translational PK-PD modelling of molecular target modulation for the AMPA receptor positive allosteric modulator Org 26576.

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21 January 2018

Prefrontal changes and treatment response prediction in depression

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21 January 2018

Early changes in prefrontal activity characterize clinical responders to antidepressants

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21 January 2018

Modulation of synaptic plasticity by antimanic agents: the role of AMPA glutamate receptor subunit 1 synaptic expression

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Low cerebrospinal fluid glutamate and glycine in refractory affective disorder.

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A placebo-controlled add-on trial of the Ampakine, CX516, for cognitive deficits in schizophrenia

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A placebo-controlled pilot study of the ampakine CX516 added to clozapine in schizophrenia

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Role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors in the control of prolactin, growth hormone and gonadotropin secretion in prepubertal rats.

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Reliability and validity of a computerized neurocognitive test battery, CNS Vital Signs.

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21 January 2018

The ampakine, Org 26576, bolsters early spatial reference learning and retrieval in the Morris water maze: a subchronic, dose-ranging study in rats.

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21 January 2018

Increased levels of glutamate in brains from patients with mood disorders.

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21 January 2018

Comparison of the effects of ketamine and memantine on prolactin and cortisol release in men. a randomized, double-blind, placebo-controlled trial

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21 January 2018

Decreased serum brain-derived neurotrophic factor levels in major depressed patients.

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21 January 2018

Antidepressant activity of memory-enhancing drugs in the reduction of submissive behavior model

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21 January 2018

Chronic elevation of brain-derived neurotrophic factor by ampakines

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21 January 2018

Regulation of BDNF expression in primary neuron culture by LY392098, a novel AMPA receptor potentiator.

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21 January 2018

Effectiveness of a quantitative electroencephalographic biomarker for predicting differential response or remission with escitalopram and bupropion in major depressive disorder

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21 January 2018

Comparative effectiveness of biomarkers and clinical indicators for predicting outcomes of SSRI treatment in Major Depressive Disorder: results of the BRITE-MD study

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21 January 2018

Changes in brain function of depressed subjects during treatment with placebo

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21 January 2018

Relationship between brain electrical activity and cortical perfusion in normal subjects.

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21 January 2018

Antidepressant-like actions of an AMPA receptor potentiator (LY392098).

1 reference

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21 January 2018

Glutamate-based therapeutic approaches: ampakines

1 reference

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21 January 2018

Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors.

1 reference

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21 January 2018

Preliminary experience with an ampakine (CX516) as a single agent for the treatment of schizophrenia: a case series

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21 January 2018

Projections of global mortality and burden of disease from 2002 to 2030

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21 January 2018

Changes in BDNF serum levels in patients with major depression disorder (MDD) after 6 months treatment with sertraline, escitalopram, or venlafaxine

1 reference

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21 January 2018

A New Depression Scale Designed to be Sensitive to Change

1 reference

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21 January 2018

Maximum tolerated dose evaluation of the AMPA modulator Org 26576 in healthy volunteers and depressed patients: a summary and method analysis of bridging research in support of phase II dose selection

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21 January 2018

Coupling of theta activity and glucose metabolism in the human rostral anterior cingulate cortex: an EEG/PET study of normal and depressed subjects

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A cognitive neuropsychological model of antidepressant drug action

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AMPA receptor potentiators: application for depression and Parkinson's disease

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Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report

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Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications

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21 January 2018

Chronic treatment with AMPA receptor potentiator Org 26576 increases neuronal cell proliferation and survival in adult rodent hippocampus

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The effect of serotonergic and noradrenergic antidepressants on face emotion processing in depressed patients

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VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants

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The size and burden of mental disorders and other disorders of the brain in Europe 2010.

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A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression

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Derivation of a definition of remission on the Montgomery-Asberg depression rating scale corresponding to the definition of remission on the Hamilton rating scale for depression.

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The 16-Item quick inventory of depressive symptomatology (QIDS), clinician rating (QIDS-C), and self-report (QIDS-SR): a psychometric evaluation in patients with chronic major depression

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21 January 2018

Identifiers

10.1177/0269881112458728

1 reference

Europe PubMed Central

13 September 2017

1 reference

Europe PubMed Central

13 September 2017

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