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RNA-Binding Proteins in Amyotrophic Lateral Sclerosis and Neurodegeneration.
scientific article published on 19 April 2012
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scholarly article
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Europe PubMed Central
PMCID
3423945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22919483%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
title
RNA-Binding Proteins in Amyotrophic Lateral Sclerosis and Neurodegeneration
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3423945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22919483%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
main subject
amyotrophic lateral sclerosis
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neurodegeneration
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based on heuristic
inferred from title
author
James Shorter
series ordinal
2
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Europe PubMed Central
PMCID
3423945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22919483%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
author name string
Scott E Ugras
series ordinal
1
1 reference
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Europe PubMed Central
PMCID
3423945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22919483%20AND%20SRC:MED&resulttype=core&format=json
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11 February 2020
publication date
19 April 2012
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Europe PubMed Central
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3423945
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22919483%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
published in
Neurology Research International
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Europe PubMed Central
PMCID
3423945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22919483%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
volume
2012
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stated in
Europe PubMed Central
PMCID
3423945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22919483%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
page(s)
432780
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stated in
Europe PubMed Central
PMCID
3423945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22919483%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
copyright license
Creative Commons Attribution 3.0 Unported
start time
1 January 2012
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April 2022 Public Data File from Crossref
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copyrighted
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0 references
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Different 8-hydroxyquinolines protect models of TDP-43 protein, α-synuclein, and polyglutamine proteotoxicity through distinct mechanisms
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Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS
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FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations
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A seeding reaction recapitulates intracellular formation of Sarkosyl-insoluble transactivation response element (TAR) DNA-binding protein-43 inclusions
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FUS/TLS forms cytoplasmic aggregates, inhibits cell growth and interacts with TDP-43 in a yeast model of amyotrophic lateral sclerosis
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Implications of the prion-related Q/N domains in TDP-43 and FUS.
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TDP-43 regulates its mRNA levels through a negative feedback loop
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TDP-43 toxicity in yeast
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Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
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ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import
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Interaction with polyglutamine aggregates reveals a Q/N-rich domain in TDP-43.
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TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity
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Rethinking ALS: the FUS about TDP-43.
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14 September 2017
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423945
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14 September 2017
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis
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PubMed Central
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14 September 2017
A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity
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14 September 2017
TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
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TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
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14 September 2017
Beer and bread to brains and beyond: can yeast cells teach us about neurodegenerative disease?
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423945
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Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
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14 September 2017
Rules for nuclear localization sequence recognition by karyopherin beta 2
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14 September 2017
Prions as adaptive conduits of memory and inheritance
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14 September 2017
Prion-like disorders: blurring the divide between transmissibility and infectivity
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423945
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14 September 2017
Neurotoxic 43-kDa TAR DNA-binding protein (TDP-43) triggers mitochondrion-dependent programmed cell death in yeast
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423945
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17 June 2018
Expression of human FUS/TLS in yeast leads to protein aggregation and cytotoxicity, recapitulating key features of FUS proteinopathy
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423945
retrieved
17 June 2018
Identifiers
DOI
10.1155/2012/432780
1 reference
stated in
Europe PubMed Central
PMCID
3423945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22919483%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
PMCID
3423945
1 reference
stated in
Europe PubMed Central
PMCID
3423945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22919483%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
PubMed ID
22919483
1 reference
stated in
Europe PubMed Central
PMCID
3423945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22919483%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
ResearchGate publication ID
230735994
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